Results 101 to 110 of about 1,342,700 (307)

The Newly Bone Formation with Carbonate Apatite-Chitosan Bone Substitute in the Rat Tibia [PDF]

open access: yes, 2011
Large bone defect still represent a major problem in orthopedics. A tissue engineering approach has been proposed where osteogenic cells, bioceramic scaffolds and growth factors can play in a role to the bone repair.
Dewi, A. H. (Anne), Triawan, A. (Andi)
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Statin: A boon in periodontal therapy

open access: yesSRM Journal of Research in Dental Sciences, 2015
Periodontitis is an inflammatory process causing gradual destruction of the periodontal tissues and alveolar bone loss. Various periodontal therapies have been introduced to lower the destruction, statin being one among them.
Sahana Purushotham   +2 more
doaj   +1 more source

Synthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic application [PDF]

open access: yes, 2016
The composite materials based on hydroxyapatite (HA) and gelatine (Gel) with addition of silver and zirconium oxide were obtained. The study investigates a combination of low powered ultrasonic irradiation and low concentration of gelatine in the co ...
Bolshanina, S.   +7 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Effects of Super-Activated Platelet Lysate on Early Healing of Tooth Extraction Sockets in Rats

open access: yesDrug Design, Development and Therapy, 2022
Xiaorui Guo,1,2 Huiying Lu,3 Chunxiang Liu,3 Yi Zhang,3 Liangjia Bi1 1Department of Stomatology, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, People’s Republic of China; 2State Key Laboratory of Military Stomatology and ...
Guo X, Lu H, Liu C, Zhang Y, Bi L
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Graft-Free Sinus Augmentation Procedure: a Literature Review

open access: yeseJournal of Oral Maxillofacial Research, 2014
Objectives: The restoration of edentulous posterior maxilla with dental implants is challenging due to a deficient posterior alveolar ridge. Over the last decade an advance in the graftless bone augmentation procedures had occurred where the space left ...
Ginnady Pinchasov, Gintaras Juodzbalys
doaj   +1 more source

Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]

open access: yes, 2014
The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio   +5 more
core   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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