Results 101 to 110 of about 7,909,245 (408)

Probability analysis of peri-implant infection following external transpedicular spine fixation

Гений oртопедии, 2021
The main purpose of spinal fixation is to provide conditions for vertebral fusion at the level of injury. Bone fusion is associated with many factors including stability of injured segment, restoration of the anterior support column, condition of the ...
Olga V. Berdiugina
doaj   +1 more source

Shell formation and bone strength in laying hens [PDF]

, 2013
In Sweden almost 3.8% of all eggs are ruined due to cracked eggshells as shell quality declines with age during the laying period. This is a concern for food safety as well as an economical problem.
Wistedt, Anna
core  

NOTUM inhibition increases endocortical bone formation and bone strength

, 2019
The disability, mortality and costs caused by non-vertebral osteoporotic fractures are enormous. Existing osteoporosis therapies are highly effective at reducing vertebral but not non-vertebral fractures.
Doree, D. D., Jeter-Jones, S., Sands, A. T., Ohlsson, Claes,, Shadoan, M. K., Vogel, P., Zambrowicz, B., Mseeh, F., Hansen, G. M., Tarver, J. E., Cui, J., Bright, D., Liu, Q. Y., Bardenhagen, J. P., Nilsson, Karin H.,, Lerner, Ulf H,, Powell, D. R., Henning, Petra,, Brommage, Robert,, Potter, D. G., Liu, J., Thompson, A. Y., Moverare-Skrtic, Sofia,   +22 more
core   +1 more source

Calcium carbonate-calcium phosphate mixed cement compositions for bone reconstruction [PDF]

, 2006
The feasibility of making calcium carbonate-calcium phosphate (CaCO3-CaP) mixed cements, comprising at least 40 % (w/w) CaCO3 in the dry powder ingredients, has been demonstrated.
Bareille, Reine, Combes, Christèle, Rey, Christian   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Therapeutic RNA interference targeting CKIP-1 with a cross-species sequence to stimulate bone formation

, 2014
Objectives: Casein kinase 2 interacting protein 1 (CKIP-1) is a newly discovered intracellular negative regulator of bone formation without affecting bone resorption.
He, Xiaojuan, Zheng, Lizhen, Lu, Aiping, He, Fuchu, Zhang, Ge, Yang, Zhijun, Liu, Jin, Qin, Ling, Zhang, Baoting, Wu, Heng, Zhang, Lingqiang, Peng, Songlin, Yue, Kevin K. M., Guo, Baosheng, Bian, Zhaoxiang, Tang, Tao, Zhang, Hongqi, Liang, Zicai, Tan, Weihong   +18 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]

, 2005
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core  

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: an ovine femoral condyle defect study

, 2014
The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required.
Oreffo, Richard O. C., Purcell, Matthew, Tayton, Edward, Dunlop, Douglas G., Shakesheff, Kevin M., Goodship, Allen, Fowler, Darren, Smith, James O., Howdle, Steven M., Oreffo, Richard O.C., Blunn, Gordon, Lanham, Stuart, Tayton, Edward R.   +12 more
core   +1 more source

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation.

Genes & Development, 1999
The mechanisms that control cell proliferation and cell differentiation during morphogenesis of the endochondral skeleton of vertebrates are poorly understood.
B. St.-Jacques, M. Hammerschmidt, A. McMahon   +2 more
semanticscholar   +1 more source