Results 121 to 130 of about 7,909,245 (408)

Glucose uptake and Runx2 synergize to orchestrate osteoblast differentiation and bone formation

open access: yesCell, 2015
Summary The synthesis of Type I collagen, the main component of the bone matrix, precedes the expression of Runx2, the earliest determinant of osteoblast differentiation.
Jianwen Wei   +10 more
semanticscholar   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

The Effect of Ultraviolet Light Exposure on the Titanium Screw Implants Osseointegration in Different Time Intervals [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: The effect of ultraviolet light on the osseointegration of titanium screw implants is scarcely discussed in literature.
M Shakir Mahmood   +4 more
doaj  

The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism

open access: yes, 2008
The ‘calcitonin family’ is a group of peptide hormones that share structural similarities with calcitonin, and includes calcitonin gene-related peptide (CGRP), amylin, adrenomedullin and adrenomedullin 2 (intermedin).
Naot, Dorit, Cornish, Jillian
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Long-term Consequences of Traumatic Brain Injury in Bone Metabolism

open access: yesFrontiers in Neurology, 2018
Traumatic brain injury (TBI) leads to long-term cognitive, behavioral, affective deficits, and increase neurodegenerative diseases. It is only in recent years that there is growing awareness that TBI even in its milder form poses long-term health ...
Nikita M. Bajwa   +5 more
doaj   +1 more source

Osteoblasts and bone formation.

open access: yesActa reumatologica portuguesa, 2007
© 2007 Sociedade Portuguesa de ...
Caetano-Lopes, Joana   +2 more
openaire   +2 more sources

A Short-Term Free-Fall Landing Enhances Bone Formation and Bone Material Properties

open access: yes, 2012
To investigate the effects of a short-term free- fall landing course on local bone metabolism and biomaterial properties, 32 female Wistar rats (7-week-old) were randomly assigned to three groups: L30 (n=11 ), L10 (n=11) and CON (n=10) groups. Animals in
LIN, HSIN-SHIH; HUANG, TSANG-HAI; MAO, SHIH-WEI; TAI, YUH-SHIOU; CHIU, HUNG-TA; CHENG, KUANG-YOU B.; YANG, RONG-SEN   +1 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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