Results 81 to 90 of about 7,909,245 (408)

Identification Of Human Cranio-Maxillofacial Skeletal Stem Cells

open access: yesInternational Dental Journal
Aim or purpose: Compared with long bone that arises from the mesoderm, the major portion of the maxillofacial bones are derived from cranial neural crest cells and undergo intramembranous ossification.
Li Liao
doaj   +1 more source

A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep

open access: yesJournal of Functional Biomaterials, 2014
The aim of the present study was to evaluate a new multi-phosphonate surface treatment (SurfLink®) in an unloaded sheep model. Treated implants were compared to control implants in terms of bone to implant contact (BIC), bone formation, and biomechanical
Marcella von Salis-Soglio   +11 more
doaj   +1 more source

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice [PDF]

open access: yes, 2010
Nearly every extracellular ligand that has been found to play a role in regulating bone biology acts, at least in part, through MAPK pathways. Nevertheless, much remains to be learned about the contribution of MAPKs to osteoblast biology in vivo. Here we
Zhai, Bo   +33 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Effective Oral Delivery of Teriparatide Using Organoclay—Polymethacrylate Nanocomposites for Osteoporosis Therapy

open access: yesPharmaceutics
Background: Although teriparatide is efficacious, its once-daily subcutaneous injections cause local adverse events, inconvenience, and higher cost, limiting long-term adherence.
Gyu Lin Kim   +4 more
doaj   +1 more source

Bone mineral density and bone turnover in male master track and field athletes aged 40-64

open access: yes, 2010
We evaluated areal bone mineral density (aBMD), bone mineral content (BMC), and markers of bone turnover in male competitive masters athletes representing different training profile in the past and at present, aged 40–64 (14 endurance runners, and 12 ...
Rittweger, Jörn   +12 more
core   +1 more source

In vivo loading increases mechanical properties of scaffold by affecting bone formation and bone resorption rates [PDF]

open access: yes, 2011
A successful bone tissue engineering strategy entails producing bone-scaffold construct with adequate mechanical properties. Apart from the mechanical properties of the scaffold itself, the forming bone inside the scaffold also adds to the strength of ...
Pioletti, Dominique   +14 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

In Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone Formation

open access: yesFrontiers in Bioengineering and Biotechnology, 2016
This review describes the role of bone cells and their surrounding matrix in maintaining bone strength through the process of bone remodeling. Subsequently, this work focusses on how bone formation is guided by mechanical forces and fluid shear stress in
C. Wittkowske   +3 more
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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