Results 91 to 100 of about 7,909,245 (408)

Could CH3-M6P Be a Potential Dual-Functioning Candidate for Bone Regeneration?

open access: yesBiomedicines
Background: CI-RM6P has different binding sites with affinities for both M6P and IGF2, plays a role in the regulation of the TGF-β and IGF pathways that is important for controlling cell growth and differentiation.
Fidan Huseynova   +5 more
doaj   +1 more source

EFFECT OF CALCITONIN INTRA MUSCULAR INJECTION ON BONE FORMATION AROUND TITANIUM DENTAL IMPLANTS IN DOGS (A HISTOLOGICAL STUDY) [PDF]

open access: yesAlexandria Dental Journal, 2017
INTRODUCTION: Calcitonin is a major hormone secreted by thyroid gland responsible for bone formation and decrease of blood calcium level. It is a mixture of amino acids plus a modifying agent.
RihamM. El Dibany   +2 more
doaj   +1 more source

Effect of psoralen on bone formation [PDF]

open access: yesJournal of Orthopaedic Research, 2010
AbstractTo compare the amount of new bone and bone cells produced by psoralen in collagen matrix to that produced by collagen matrix in vivo. Eighteen bone defects, 5 mm by 10 mm were created in the parietal bone of nine New Zealand White rabbits. Six defects were grafted with psoralen mixed with collagen matrix.
Wong, RWK, Rabie, ABM
openaire   +4 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Green Tea Extract Containing Epigallocatechin-3-Gallate Facilitates Bone Formation and Mineralization by Alleviating Iron-Overload-Induced Oxidative Stress in Human Osteoblast-like (MG-63) Cells

open access: yesAntioxidants
Secondary iron overload exacerbates osteoporosis by elevating reactive oxygen species (ROS), which suppress osteoblast function and enhance osteoclast activity, disrupting bone remodeling.
Honghong Xu   +7 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk   +5 more
core   +1 more source

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

open access: yes, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo   +14 more
core   +1 more source

Bone strength and performance parameters in Japanese collegiate American football players

open access: yes, 2022
Seventy percent of bone strength depends on adequate bone mineral density. To date, there has been little research on bone strength of Japanese collegiate American football players.
井口, 順太   +24 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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