Results 91 to 100 of about 1,342,700 (307)
Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice [PDF]
, 2019 Astronauts traveling beyond low Earth orbit will be exposed to galactic cosmic radiation (GCR); understanding how high energy ionizing radiation modifies the bone response to mechanical unloading is important to assuring crew health. To investigate this,
Allen, Matthew R. +9 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Importance of geometry of the extracellular matrix in endochondral bone differentiation. [PDF]
, 1984 Subcutaneous implantation of coarse powders (74-420 micron) of demineralized diaphyseal bone matrix resulted in the local differentiation of endochondral bone.
Reddi, AH, Sampath, TK
core +1 more source
Osteoblasts and bone formation.
Acta reumatologica portuguesa, 2007 © 2007 Sociedade Portuguesa de ...
Caetano-Lopes, Joana +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Effect of Ultraviolet Light Exposure on the Titanium Screw Implants Osseointegration in Different Time Intervals [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: The effect of ultraviolet light on the osseointegration of titanium screw implants is scarcely discussed in literature.
M Shakir Mahmood +4 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Acidosis Is a Key Regulator of Osteoblast Ecto-Nucleotidase Pyrophosphatase/Phosphodiesterase 1 (NPP1) Expression and Activity [PDF]
, 2015 Previous work has shown that acidosis prevents bone nodule formation by osteoblasts in vitro by inhibiting mineralisation of the collagenous matrix.
Arnett, T R +4 more
core +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Long-term Consequences of Traumatic Brain Injury in Bone Metabolism
Frontiers in Neurology, 2018 Traumatic brain injury (TBI) leads to long-term cognitive, behavioral, affective deficits, and increase neurodegenerative diseases. It is only in recent years that there is growing awareness that TBI even in its milder form poses long-term health ...
Nikita M. Bajwa +5 more
doaj +1 more source