Strategies of Macrophages to Maintain Bone Homeostasis and Promote Bone Repair: A Narrative Review [PDF]
Journal of Functional Biomaterials, 2022 Bone homeostasis (a healthy bone mass) is regulated by maintaining a delicate balance between bone resorption and bone formation. The regulation of physiological bone remodeling by a complex system that involves multiple cells in the skeleton is closely ...
Yingkun Hu +7 more
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Osteoblast-Osteoclast Communication and Bone Homeostasis [PDF]
Cells, 2020 Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to regulate cellular behavior, survival and differentiation through direct cell ...
Jung-Min Kim +4 more
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Bone Morphogenetic Protein-2 in Development and Bone Homeostasis [PDF]
Journal of Developmental Biology, 2020 Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many developmental processes, including cardiogenesis, neurogenesis, and ...
Daniel Halloran +2 more
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Healthy bone tissue homeostasis [PDF]
Experimental and Molecular Medicine, 2020 Je-Yong Choi
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Exosomal communication: a pivotal regulator of bone homeostasis and a potential therapeutic target [PDF]
Frontiers in PharmacologyBone homeostasis encompasses two interrelated aspects: bone remodeling and cartilage metabolism. Disruption of bone homeostasis can lead to the development of metabolic bone diseases such as osteoporosis and osteoarthritis.
Qian-Yun Ye +11 more
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Current advances of bone homeostasis imbalance in the cause of hereditary metabolic bone diseases [PDF]
EFORT Open ReviewsBone homeostasis, a dynamic equilibrium essential for skeletal development and repair, is coordinately regulated by osteoclasts, osteoblasts, and osteocytes.
Xinyu Dai +4 more
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Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies [PDF]
Military Medical ResearchThe skeleton is innervated by different types of nerves and receives signaling from the nervous system to maintain homeostasis and facilitate regeneration or repair.
Tong-Zhou Liang +7 more
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Influence of Iron on Bone Homeostasis [PDF]
Pharmaceuticals, 2018 Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be tightly regulated and orchestrated.
Enikő Balogh +2 more
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Regulation of bone homeostasis: signaling pathways and therapeutic targets [PDF]
MedCommAs a highly dynamic tissue, bone is continuously rebuilt throughout life. Both bone formation by osteoblasts and bone resorption by osteoclasts constitute bone reconstruction homeostasis.
Zebin Wu +11 more
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ER-resident proteins are key players in cartilage and bone homeostasis. [PDF]
Front Cell Dev BiolStücker S +3 more
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