Results 11 to 20 of about 399,329 (296)

Osteoblast-Osteoclast Communication and Bone Homeostasis [PDF]

open access: yesCells, 2020
Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to regulate cellular behavior, survival and differentiation through direct cell ...
Jung-Min Kim   +4 more
doaj   +4 more sources

Healthy bone tissue homeostasis [PDF]

open access: yesExperimental and Molecular Medicine, 2020
Je-Yong Choi
doaj   +3 more sources

Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies [PDF]

open access: yesMilitary Medical Research
The skeleton is innervated by different types of nerves and receives signaling from the nervous system to maintain homeostasis and facilitate regeneration or repair.
Tong-Zhou Liang   +7 more
doaj   +2 more sources

Dicer1 ablation in osterix positive bone forming cells affects cortical bone homeostasis [PDF]

open access: yes, 2022
The RNAse III enzyme Dicer plays a major role in the processing of microRNAs from large pre-miRNAs. Dicer1 processed microRNAs are known to play a comprehensive role in osteoblast differentiation, bone remodeling and skeletal disorders. Targeted deletion
Bendre A   +3 more
core   +2 more sources

Roles of the Siglec family in bone and bone homeostasis

open access: yesBiomedicine & Pharmacotherapy, 2023
Tremendous progress has been seen in the study of the role of sialic acid binding im-munoglobulin type lectins (Siglecs) in osteoimmunology in the past two decades. Interest in Siglecs as immune checkpoints has grown from the recognition that Siglecs have relevance to human disease.
Zi Ye   +9 more
openaire   +2 more sources

Bone mineral as a drug-seeking moiety and a waste dump [PDF]

open access: yes, 2020
Bone is a dynamic tissue with a quarter of the trabecular and a fifth of the cortical bone being replaced continuously each year in a complex process that continues throughout an individual’s lifetime.
Liu, Y   +11 more
core   +3 more sources

Recent Progress in Osteocyte Research [PDF]

open access: yesEndocrinology and Metabolism, 2013
The last decade has seen an exponential increase in our understanding of osteocytes function and biology. These cells, once considered inert by-standers trapped into the mineralized bone, has now risen to be key regulators of skeletal metabolism, mineral
Paola Divieti Pajevic
doaj   +1 more source

MicroRNAs as regulators of bone homeostasis and bone metastasis [PDF]

open access: yesbonekey Reports, 2014
MicroRNAs (miRNAs) are short, endogenous RNAs that have essential roles in regulating gene expression through the disruption of target genes. The miRNA-induced suppression can occur through Argonaute-mediated cleavage of target mRNAs or by translational inhibition.
Brian, Ell, Yibin, Kang
openaire   +2 more sources

Peripheral nerves in the tibial subchondral bone: the role of pain and homeostasis in osteoarthritis

open access: yesBone & Joint Research, 2022
Osteoarthritis (OA) is a highly prevalent degenerative joint disorder characterized by joint pain and physical disability. Aberrant subchondral bone induces pathological changes and is a major source of pain in OA.
Qi Sun   +6 more
doaj   +1 more source

Break and then stand: novel insight into osteoclast functions in the skeletal system

open access: yesDi-san junyi daxue xuebao, 2022
The skeleton provides the scaffold to support body weight, enable body movement, control mineral homeostasis, and provide the location for hematopoiesis.
DONG Shiwu, HU Wenhui
doaj   +1 more source

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