Macrophage Polarization and the Regulation of Bone Immunity in Bone Homeostasis [PDF]
Journal of Inflammation Research, 2023 Kangyi Hu, Zhengya Shang, Xiaorui Yang, Yongjie Zhang, Linzhong Cao Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, People’s Republic of ChinaCorrespondence: Linzhong Cao, Clinical College of Traditional ...
Hu K, Shang Z, Yang X, Zhang Y, Cao L
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Influence of Iron on Bone Homeostasis [PDF]
Pharmaceuticals, 2018 Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be tightly regulated and orchestrated.
Enikő Balogh +2 more
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Strategies of Macrophages to Maintain Bone Homeostasis and Promote Bone Repair: A Narrative Review [PDF]
Journal of Functional Biomaterials, 2022 Bone homeostasis (a healthy bone mass) is regulated by maintaining a delicate balance between bone resorption and bone formation. The regulation of physiological bone remodeling by a complex system that involves multiple cells in the skeleton is closely ...
Yingkun Hu +7 more
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Role of SIRT3 in bone homeostasis and its application in preventing and treating bone diseases [PDF]
Frontiers in Pharmacology, 2023 Bone homeostasis refers to the balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption and the maintenance of stable bone mass. SIRT3 is a class of mitochondrial protein deacetylase that influences various mitochondrial
Ke Xu +5 more
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Extracellular purines and bone homeostasis [PDF]
Biochemical Pharmacology, 2021 Maintenance of a healthy skeleton is highly dependent on an intricate regulation of bone metabolism, as changes in the balance between bone formation and bone resorption leads to bone loss, bone fragility and ultimately bone fractures. During the last three decades it has become increasingly evident that physiological release of purines in the ...
Agrawal, Ankita, Jørgensen, Niklas R.
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Bone Morphogenetic Protein-2 in Development and Bone Homeostasis [PDF]
Journal of Developmental Biology, 2020 Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many developmental processes, including cardiogenesis, neurogenesis, and ...
Daniel Halloran +2 more
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Regulation of bone homeostasis: signaling pathways and therapeutic targets
MedCommAs a highly dynamic tissue, bone is continuously rebuilt throughout life. Both bone formation by osteoblasts and bone resorption by osteoclasts constitute bone reconstruction homeostasis.
Zebin Wu +11 more
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Non-bone-derived exosomes: a new perspective on regulators of bone homeostasis [PDF]
Cell Communication and SignalingAccumulating evidence indicates that exosomes help to regulate bone homeostasis. The roles of bone-derived exosomes have been well-described; however, recent studies have shown that some non-bone-derived exosomes have better bone targeting ability than ...
Ping Wang +6 more
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Current advances of bone homeostasis imbalance in the cause of hereditary metabolic bone diseases [PDF]
EFORT Open ReviewsBone homeostasis, a dynamic equilibrium essential for skeletal development and repair, is coordinately regulated by osteoclasts, osteoblasts, and osteocytes.
Xinyu Dai +4 more
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Exosomal communication: a pivotal regulator of bone homeostasis and a potential therapeutic target [PDF]
Frontiers in PharmacologyBone homeostasis encompasses two interrelated aspects: bone remodeling and cartilage metabolism. Disruption of bone homeostasis can lead to the development of metabolic bone diseases such as osteoporosis and osteoarthritis.
Qian-Yun Ye +11 more
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