Results 11 to 20 of about 1,620,642 (265)
Bone marrow cell cycle markers in inherited bone marrow failure syndromes [PDF]
Leukemia Research, 2008 Patients with inherited bone marrow failure syndromes (IBMFS) are at increased risk of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), possibly related to cell cycle dysregulation. In a cross-sectional analysis of bone marrow from 77 IBMFS, 71 sporadic conditions (AML, MDS, acquired aplastic anemia) and 22 normal controls we found ...
Mohamad M, Al-Rahawan +3 more
openaire +2 more sources
JBMR Plus, 2023 Mesenchymal stem cell (MSC) therapy is a promising approach to curing bone diseases and disorders. In treating genetic bone disorders, MSC therapy is local or systemic transplantation of isolated and in vitro proliferated MSC rather than bone marrow ...
Hotaka Kawai +11 more
doaj +1 more source
The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]
, 2018 Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin +6 more
core +2 more sources
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Nature Medicine, 2012 Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado +24 more
semanticscholar +1 more source
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
Science, 2021 Getting around the blood–brain barrier The meninges comprise three membranes that surround and protect the central nervous system (CNS). Recent studies have noted the existence of myeloid cells resident there, but little is known about their ontogeny and
A. Cugurra +16 more
semanticscholar +1 more source
Journal of Tissue Engineering, 2020 Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural crest, have the character of easily obtained and strong multi-differential ...
Yanan Liu +7 more
doaj +1 more source
Cytokines inducing bone marrow SCA+ cells migration into pancreatic islet and conversion into insulin-positive cells in vivo. [PDF]
PLoS ONE, 2009 We hypothesize that specific bone marrow lineages and cytokine treatment may facilitate bone marrow migration into islets, leading to a conversion into insulin producing cells in vivo.
LuGuang Luo +4 more
doaj +1 more source
A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus [PDF]
, 1976 A quantitative Abelson murine leukemia virus (A-MuLV) lymphoid cell transformation assay has been developed using a semisolid agarose culture system. Under these conditions lymphoid cell transformation was shown to vary linearly with the dose of A-MuLV ...
Baltimore, David, Rosenberg, Naomi
core +1 more source
Journal of Experimental Medicine, 1992 Antigen-presenting, major histocompatibility complex (MHC) class II- rich dendritic cells are known to arise from bone marrow. However, marrow lacks mature dendritic cells, and substantial numbers of proliferating less-mature cells have yet to be ...
K. Inaba +7 more
semanticscholar +1 more source
Bone Marrow Microenvironment-On-Chip for Culture of Functional Hematopoietic Stem Cells
Frontiers in Bioengineering and Biotechnology, 2022 Hematopoiesis takes place in the bone marrow and is supported by a complex cellular and molecular network in the bone marrow microenvironment. Commonly used models of the human bone marrow microenvironment include murine models and two-dimensional and ...
Azmeer Sharipol +8 more
doaj +1 more source