Bone Marrow: The Central Immune System
Bone marrow is known as the site of hematopoiesis. What is not being described in textbooks of immunology is the fact that bone marrow is not only a generative, but also an antigen-responsive, immune organ.
Volker Schirrmacher
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Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Andratschke, M.+5 more
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The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]
Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin+6 more
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A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus [PDF]
A quantitative Abelson murine leukemia virus (A-MuLV) lymphoid cell transformation assay has been developed using a semisolid agarose culture system. Under these conditions lymphoid cell transformation was shown to vary linearly with the dose of A-MuLV ...
Baltimore, David, Rosenberg, Naomi
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IFNα-mediated remodeling of endothelial cells in the bone marrow niche
In the bone marrow, endothelial cells are a major component of the hematopoietic stem cell vascular niche and are a first line of defense against inflammatory stress and infection.
Áine M. Prendergast+5 more
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Spindle cell lesion in the bone marrow [PDF]
![Figure][1] A 60-year-old man with myeloma treated with lenalidomide-bortezomib-dexamethasone (4 cycles) and carfilzomib-cyclophosphamide-dexamethasone (4 cycles) presented for a routine follow-up bone marrow scan.
Sumire Kitahara, Samuel Guzman
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Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Aicher, A+8 more
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Toxic effects of various zinc dosages on poultry hemopoiesis [PDF]
The aim of the study was to determine the main patterns of the manifestation of the toxic effect of zinc chloride on the cells of the red bone marrow in the first three days after exposure. Our experiment involved broiler chickens of the “Smena-7” cross.
Vishnyakov Aleksandr
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Bone Marrow Cell Recognition: Training Deep Object Detection with A New Loss Function [PDF]
For a long time, bone marrow cell morphology examination has been an essential tool for diagnosing blood diseases. However, it is still mainly dependent on the subjective diagnosis of experienced doctors, and there is no objective quantitative standard.
arxiv
Tracking intracavernously injected adipose-derived stem cells to bone marrow. [PDF]
The intracavernous (i.c.) injection of stem cells (SCs) has been shown to improve erectile function in various erectile dysfunction (ED) animal models. However, the tissue distribution of the injected cells remains unknown.
Banie, L+6 more
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