Results 141 to 150 of about 125,148 (266)

Effects of fatty acids and cholesterol on functions and behavior of bone marrow mesenchymal stem cells. [PDF]

open access: yesiScience
Gonzalez-Garcia B   +6 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

open access: yesBMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu   +8 more
wiley   +1 more source

Bacterial backpacks for targeted delivery of piezoelectric nanoparticles to enhance sonodynamic immunotherapy

open access: yesBMEMat, EarlyView.
Leveraging bacterial hypoxia targeting, KBTO NPs accumulate at the tumor site. Under the ultrasound irradiation, KBTO NPs produce reactive oxygen species to kill tumor cells and eliminate bacteria, preventing overgrowth and inflammation. The lysed bacteria act as antigens to trigger antitumor immunity and further enhanced by the immune checkpoint ...
Chongyang Liu   +12 more
wiley   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Review of articular cartilage repair techniques and their application in the horse

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton   +2 more
wiley   +1 more source

Engineered Nature‐Based Sonosensitizer for Broad‐Spectrum Infectious Tissue Repair via Sono‐Ionic Therapy

open access: yesExploration, EarlyView.
A schematic illustration of an engineered nature‐based sonosensitizer enables early‐stage high‐power ultrasound to generate substantial reactive oxygen species for antibacterial effects and late‐stage low‐power sono‐ionic therapy for infected bone repair, infected wound biofilm therapy, and wound regeneration.
Liang Ma   +13 more
wiley   +1 more source

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