Results 31 to 40 of about 1,205,734 (289)
Bone Marrow Adipocyte: An Intimate Partner With Tumor Cells in Bone Metastasis
Frontiers in Endocrinology, 2018 The high incidences of bone metastasis in patients with breast cancer, prostate cancer and lung cancer still remains a puzzling issue. The “seeds and soil” hypothesis suggested that bone marrow (soil) may provide a favorable “niche” for tumor cells (seed)
Guojing Luo, Yuedong He, Xijie Yu
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Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]
, 2004 Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A. +5 more
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Pathological Crosstalk between Metastatic Breast Cancer Cells and the Bone Microenvironment
Biomolecules, 2020 Bone is the most common metastatic site in breast cancer. Upon arrival to the bone, disseminated tumor cells can undergo a period of dormancy but often eventually grow and hijack the bone microenvironment.
Jennifer Zarrer +3 more
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Isolation and characterization of mesenchymal stem cells from cultured human pancreatic islets of langerhans [PDF]
, 2006 Replacement of insulin producing β-cells that reside within pancreatic islets represents an almost ideal treatment for patients with diabetes mellitus type 1.
Eberhardt, Michael
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Injectable Cell-based Tissue Engineered Bone Formulations [PDF]
, 2010 PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
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Metabolic crosstalk between stromal and malignant cells in the bone marrow niche
Bone Reports, 2023 Bone marrow is the primary site of blood cell production in adults and serves as the source of osteoblasts and osteoclasts that maintain bone homeostasis.
Hernán A. Tirado +4 more
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Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma [PDF]
, 1991 The effect of murine cytomegalovirus on myelopoiesis was studied in long-term bone marrow culture to find an in vitro correlate for the lethal virus interference with bone marrow reconstitution (W. Mutter, M. J. Reddehase, F. W. Busch, H.-J. Bühring, and
Busch, Friedrich W. +3 more
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Neural regulation of bone, marrow, and the microenvironment
Frontiers in Bioscience, 2011 Bone marrow niches are specialized microenvironments comprising a heterogeneous population of cells that support and regulate hematopoietic stem and progenitor cells. Considerable advances made in the field of hematopoiesis reveal a cross talk between cells, cytokines and neurotransmitters of the hematopoietic, immune and skeletal systems.
Jonathan, Canaani +2 more
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The interplay of leukemia cells and the bone marrow microenvironment [PDF]
Blood, 2018 Abstract The interplay of cancer cells and surrounding stroma is critical in disease progression. This is particularly evident in hematological malignancies that infiltrate the bone marrow and peripheral lymphoid organs. Despite clear evidence for the existence of these interactions, the precise repercussions on the growth of leukemic ...
Duarte, D, Hawkins, ED, Lo Celso, C
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Frontiers in Oncology, 2022 Virtually all patients with multiple myeloma become unresponsive to treatment with proteasome inhibitors over time. Relapsed/refractory multiple myeloma is accompanied by the clonal evolution of myeloma cells with heterogeneous genomic aberrations ...
Jonas Schwestermann +3 more
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