Results 51 to 60 of about 2,554,329 (307)

Relationship of Tumor Markers and Hilar Lymph Nodes with Bone Metastasis of Whole Body Bone Imaging in Lung Adenocarcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the relationship between tumor markers of lung cancer and bone metastasis of whole body bone imaging in lung adenocarcinoma. Methods The whole body bone imaging of 278 patients diagnosed as lung adenocarcinoma in our hospital was
CAO Zhongnian   +5 more
doaj   +1 more source

MAZ promotes prostate cancer bone metastasis through transcriptionally activating the KRas-dependent RalGEFs pathway

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Clinically, prostate cancer (PCa) exhibits a high avidity to metastasize to bone. Myc-associated zinc-finger protein (MAZ) is a well-documented oncogene involved in the progression and metastasis of multiple cancer types, even in PCa. However,
Qing Yang   +9 more
doaj   +1 more source

Bone Metastasis From Gastric Adenocarcinoma—What Are the Risk Factors and Associated Survival? A Large Comprehensive Population-Based Cohort Study

open access: yesFrontiers in Oncology, 2022
BackgroundWhile bone metastasis is not common in gastric adenocarcinoma (GaC), it can have important impacts on prognosis. This large cohort study aimed at exploring factors associated with bone metastasis in GaC and investigating the time-dependent ...
Lei Huang   +7 more
doaj   +1 more source

Tumor metastasis to bone [PDF]

open access: yesArthritis Research & Therapy, 2007
Establishment of skeletal metastasis involves bidirectional interactions between the tumor cell and the cellular elements in the bone microenvironment. A better understanding of the pathophysiology of bone metastasis will be critical in developing the means to prevent bone metastasis or inhibit its progression.
Virk, Mandeep S, Lieberman, Jay R
openaire   +2 more sources

Restoring Tissue Homeostasis at Metastatic Sites: A Focus on Extracellular Vesicles in Bone Metastasis

open access: yesFrontiers in Oncology, 2021
Bone is the most common site of cancer metastasis and the spread of cancer cells to the bone is associated with poor prognosis, pain, increased risk of fractures, and hypercalcemia.
Domenica Giannandrea   +5 more
doaj   +1 more source

Long non-coding RNA NEAT1 promotes bone metastasis of prostate cancer through N6-methyladenosine

open access: yesMolecular Cancer, 2020
Background N6-methyladenosine (m6A) is the most prevalent messenger RNA modification in mammalian cells. However, the disease relevant function of m6A on specific oncogenic long non-coding RNAs (ncRNAs) is not well understood. Methods We analyzed the m6A
Simeng Wen   +5 more
semanticscholar   +1 more source

MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis

open access: yesAutophagy, 2020
The function of mitophagy in cancer is controversial. ULK1 is critical for induction of macroautophagy/autophagy and has a more specific role in mitophagy in response to hypoxia.
R. Deng   +16 more
semanticscholar   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

Survival Analysis in Gastrointestinal Neuroendocrine Carcinoma With Bone Metastasis at Diagnosis

open access: yesFrontiers in Surgery, 2022
PurposeGastrointestinal neuroendocrine carcinoma (NEC) with bone metastasis is rarely reported. The purpose of this study is to explore the prognosis and risk factors of such patients.Patients and MethodsWe retrospectively reviewed patients diagnosed as ...
Genlian Chen   +4 more
doaj   +1 more source

Models of Bone Metastasis

open access: yesJournal of Visualized Experiments, 2012
Bone metastases are a common occurrence in several malignancies, including breast, prostate, and lung. Once established in bone, tumors are responsible for significant morbidity and mortality. Thus, there is a significant need to understand the molecular mechanisms controlling the establishment, growth and activity of tumors in bone.
J Preston, Campbell   +4 more
openaire   +3 more sources

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