Results 21 to 30 of about 205,288 (347)

Differences in the pattern and regulation of mineral deposition in human cell lines of osteogenic and non-osteogenic origin [PDF]

, 2011
Bone marrow-derived mesenchymal stem cells (MSCs) are widely used as a cellular model of bone formation, and can mineralize in vitro in response to osteogenic medium (OM).
Alexander J. Blake, Amatschek S., Andrews P.W., Andrews P.W., Beresford J.N., Blumberg P., Boland G.M., Bonewald L.F., Boskey A.L., Boskey A.L., Boylan M.O., Briggs T., Bruder S.P., Buttery L.D., Cancedda R., Chadalavada R.S., Cheng S.L., Clover J., Cristina Tufarelli, Declercq H.A., Draper J.S., Duran C., Eijken M., Gang E.J., Gentleman E., Gey G.O., Graham F.L., Gregory C.A., Halleux C., Hassan Rashidi, Hui M., Iba K., Ilse G., Izbicka E., Jackson L., Jaiswal N., Jaiswal R.K., Jorgensen N.R., Kasten P., Khosla S., Khouja H.I., Kimelman N., Kniss D.A., Kochanowska I.E., Kochanowska I.E., Koeneman K.S., Leigh Jackson, Lin D.L., Liu F., Louise France, Maeda S., Mareschi K., Marie P.J., Markovic M., McCulloch C.A., Morgan M.P., Okamoto T., Ostrowski K., Pal R., Palmieri A., Park K.W., Pautke C., Pera M.F., Peter S.J., Pittenger M.F., Poliard A., Rago R., Rodríguez J.P., Russell R.G., Seib F.P., Shukunami C., Simoes P.D., Song I.H., Sottile V., Sottile V., Spandan Kalra, Spiropoulos A., Stephanie Strohbuecker, Tang N., Tataria M., Tenenbaum H.C., Thomas P., Tremoleda J.L., Virginie Sottile, Yu P.B., Zayzafoon M., zur Nieden N.I.   +86 more
core   +1 more source

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Bone Morphogenetic Protein as Bone Additive around Dental Implant and its Impact on Osseointegration: a Systematic Review [PDF]

Journal of Dentistry, 2022
Statement of the Problem: Bone morphogenetic protein (BMP), a potential osteoinductive agent, was systematically reviewed for merits and demerits when used as a bone additive that was intervened during the surgical phase of dental implant placement; and ...
Fathima Banu Raza , Sivakumar Vijayaragavalu , Anand Kumar Vaidyanathan   +2 more
doaj   +1 more source

Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells

Journal of Tissue Engineering, 2012
The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau, Mimmi Patrikoski, Miia Juntunen, Kasperi Kujala, Minna Kääriäinen, Hannu Kuokkanen, George K Sándor, Outi Vapaavuori, Riitta Suuronen, Bettina Mannerström, Brigitte von Rechenberg, Susanna Miettinen   +11 more
doaj   +1 more source

An osteoinductive and biodegradable intramedullary implant accelerates bone healing and mitigates complications of bone transport in male rats

Nature Communications, 2023
Bone transport is a surgery-driven procedure for the treatment of large bone defects. However, challenging complications include prolonged consolidation, docking site nonunion and pin tract infection.
Sien Lin, Hirotsugu Maekawa, Seyedsina Moeinzadeh, Elaine Lui, Hossein Vahid Alizadeh, Jiannan Li, Sungwoo Kim, Michael Poland, Benjamin C. Gadomski, Jeremiah T. Easley, Jeffrey Young, Michael Gardner, David Mohler, William J. Maloney, Yunzhi Peter Yang   +14 more
doaj   +1 more source

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas, Henrich, Dirk, Marzi, Ingo, Seebach, Caroline, Warzecha, Jörg, Wenger, Florian   +5 more
core   +1 more source

Effects of Bone Morphogenetic Protein-2 on Neovascularization During Large Bone Defect Regeneration

Tissue Engineering. Part A, 2019
Insufficient blood vessel supply is a primary limiting factor for regenerative approaches to large bone defect repair. Recombinant bone morphogenetic protein-2 (BMP-2) delivery induces robust bone formation and has been observed to enhance ...
Hope B. Pearson, Devon E. Mason, Christopher D. Kegelman, Liming Zhao, James H. Dawahare, M. Kacena, J. Boerckel   +6 more
semanticscholar   +1 more source

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling [PDF]

, 2014
Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8.
Campbell, David, Dingwell, Kevin S., Gourlay, Robert, Herhaus, Lina, Macartney, Thomas, Sapkota, Gopal P., Smith, James C., Vogt, Janis   +7 more
core   +3 more sources

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713]

Journal of Cell Biology, 1994
The implantation of bone morphogenetic protein (BMP) into muscular tissues induces ectopic bone formation at the site of implantation. To investigate the mechanism underlying this process, we examined whether recombinant bone morphogenetic protein-2 (BMP-
T. Katagiri, Akira Yamaguchi, M. Komaki, E. Abe, N. Takahashi, T. Ikeda, V. Rosen, J. Wozney, A. Fujisawa-Sehara, T. Suda   +9 more
semanticscholar   +1 more source