Results 181 to 190 of about 78,836 (261)

Controlled release of bone morphogenetic protein-2 improves motor function after traumatic brain injury in a rat model.

J Mater Chem B
Townsend JM, Deng JZ, Barbay S, Andrews BT, Guggenmos DJ, Nudo RJ, Detamore MS.   +6 more
europepmc   +1 more source

Bone morphogenetic protein receptor 2 signaling mediates mitochondrial Ca²⁺ transport through its regulation of TAK1 splice variant. [PDF]

Cell Commun Signal
Toussaint A, Singh M, Chiou H, Wang G, Jia D, Driscoll M, Bhatt V, Ndong JC, Shuaib S, Zoltowski H, Gilleran J, Peng Y, Tsymbal A, Roberge J, Guo JY, Herranz D, Langenfeld J.   +16 more
europepmc   +1 more source

Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy

Experimental Physiology, EarlyView.
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen, Moritz Eggelbusch, Rob C. I. Wüst   +2 more
wiley   +1 more source

The role of the bone morphogenetic protein receptor 2 pathway in group 2 pulmonary hypertension secondary to valvular heart disease. [PDF]

ERJ Open Res
Martínez-Solano J, Bermejo-Fernández J, González-Mansilla A, García-Orta R, Sánchez-Fernández PL, Castaño M, Segovia-Cubero J, Escribano-Subías P, Bayés-Genís A, Martínez-Legazpi P, Mombiela T, Ortiz-Bautista C, González A, Bermejo J, Fernández-Avila AI.   +14 more
europepmc   +1 more source

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

The Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani, Rin Midorikawa, Akari Kasuya, Saki Noguchi, Kohei Yamamoto, Tomohiro Nishimura, Hirokazu Kaji, Takeshi Hori, Masatoshi Tomi   +8 more
wiley   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

Bone morphogenetic protein 10 is increased in pre-capillary pulmonary hypertension patients. [PDF]

Cardiovasc Res
Llucià-Valldeperas A, van Wezenbeek J, Groeneveldt JA, Smal R, Sánchez-Duffhues G, Becher C, Kianzad A, Jansen SMA, Wessels JN, Handoko ML, Meijboom LJ, Marcus JT, Symersky P, Niessen HWM, Vonk-Noordegraaf A, Bogaard HJ, Goumans MJ, de Man FS.   +17 more
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients. [PDF]

J Clin Hypertens (Greenwich)
Zhang S, Ma M, Li P, Yao S, Wang C, Wang X, He K, Xue H.   +7 more
europepmc   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

American Journal of Hematology, Volume 101, Issue 9, Page 2105-2122, September 2026.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim, Nuttanan Pholngam, Rattanawan Thubthed, Tiwaporn Nualkaew, Saovaros Svasti, Pornthip Chaichompoo, Kai Kysenius, Peter J. Crouch, Sibylle Dames, Mona Eisermann, Alberto Martinez, Ute Schaeper, Jim Vadolas, George Grigoriadis   +13 more
wiley   +1 more source