Results 41 to 50 of about 76,730 (157)

Controlled spatial and conformational display of immobilised bone morphogenetic protein-2 and osteopontin signalling motifs regulates osteoblast adhesion and differentiation in vitro

BMC Biology, 2010
Background The interfacial molecular mechanisms that regulate mammalian cell growth and differentiation have important implications for biotechnology (production of cells and cell products) and medicine (tissue engineering, prosthetic implants, cancer ...
McCaskie Andrew W, Chaffey Benjamin T, Mitchell Elizabeth A, Lakey Jeremy H, Birch Mark A   +4 more
doaj   +1 more source

Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody

BMC Research Notes, 2019
Objective The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the transforming growth factor (TGFβ) superfamily.
Ruthann E. Gorrell, Madeline H. Totten, Laura J. Schoerning, Jordan B. Newby, Logan J. Geyman, Warren G. Lawless, Julia M. Hum, Jonathan W. Lowery   +7 more
doaj   +1 more source

The Use of Platelet Rich Plasma, Bone Morphogenetic Protein-2 and Different Scaffolds in Oral and Maxillofacial Surgery - Literature Review in Comparison with Own Clinical Experience

eJournal of Oral Maxillofacial Research, 2011
Objectives: The purpose of this article was to review and critically assess the use of platelet rich plasma, recombinant human bone morphogenetic protein-2 and different scaffolds (i.e. tricalciumphosphate, polycaprolactone, demineralized bone matrix and
Karl-Heinz Schuckert, Stefan Jopp, Magdalena Osadnik   +2 more
doaj  

Osteogenic Potential of Osteolforte: Gene and Protein-Level Evaluation in Human Bone Marrow Stromal Cells

Current Issues in Molecular Biology
Osteolforte, a compound with potential bone-regenerative properties, was investigated for its effects on human bone marrow stromal cells (hBMSCs). This study aimed to evaluate its impact on cell viability, osteogenic differentiation, and both gene and ...
Da-Sol Kim, Soo-Kyung Bae, Yeon-Ju Kwak, Geum-Joung Youn, Hye-Ock Jang   +4 more
doaj   +1 more source

Interleukin 17 enhances bone morphogenetic protein-2-induced ectopic bone formation

Scientific Reports, 2018
Interleukin 17 (IL-17) stimulates the osteogenic differentiation of progenitor cells in vitro through a synergy with bone morphogenetic protein (BMP)-2. This study investigates whether the diverse responses mediated by IL-17 in vivo also lead to enhanced
M. Croes, M. C. Kruyt, W. M. Groen, K. M. A. van Dorenmalen, W. J. A. Dhert, F. C. Öner, J. Alblas   +6 more
doaj   +1 more source

High-Density Lipoproteins from Coronary Artery Disease and Aortic Valve Stenosis Patients Differentially Regulate Gene Expression in a Model of Cardiac Adipocytes

Cells
Previous reports have described a statistical association between high-density lipoproteins (HDL) subclasses and the expression of genes coding for pro-calcifying proteins in the epicardial adipose tissue of patients with coronary artery disease (CAD ...
María Luna-Luna, Araceli Páez, Felipe Massó, Rebeca López-Marure, Jorge Moisés Zozaya-García, Ariana Vargas-Castillo, Daniel Gómez-Pineda, Armando R. Tovar, Jonathan J. Magaña, José Manuel Fragoso, Margarita Gutiérrez-Saldaña, Zuriel Téllez-Osorio, Óscar Pérez-Méndez   +12 more
doaj   +1 more source

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

Haematologica, 2009
Background The circulating hormone hepcidin plays a central role in iron homeostasis. Our goal was to establish an ex vivo iron-sensing model and to characterize the molecular mechanisms linking iron to hepcidin.Design and Methods Murine hepatocytes were
Guillemette Ramey, Jean-Christophe Deschemin, Sophie Vaulont   +2 more
doaj   +1 more source

Bone morphogenetic proteins: basic concepts [PDF]

Neurosurgical Focus, 2002
The cellular and molecular events governing bone formation in the embryo, healing of a fractured bone, and induced bone fusion follow a similar pattern. Discovery, purification, and recombinant synthesis of bone morphogenetic proteins (BMPs) constiute a major milestone in the understanding of bone physiology.
openaire   +2 more sources

Overview of Bone Morphogenetic Proteins [PDF]

Spine, 2002
A literature review was conducted.To review the discovery of the bone morphogenetic proteins and describe the bone morphogenetic protein products that will or may be available for clinical use.Bone morphogenetic proteins comprise the osteoinductive component of several tissue engineering products in late-stage development as replacements for autogenous
openaire   +2 more sources

Potentiating effect of AMD3100 on bone morphogenetic protein-2 induced bone regeneration

Maxillofacial Plastic and Reconstructive Surgery
Background AMD3100, a CXCR4 antagonist, is currently prescribed for activating the mobilization of hematopoietic stem cells. Recently, AMD3100 was shown to potentiate bone morphogenetic protein-2 (BMP-2)-induced bone formation by stimulating the ...
Gyu-Jo Shim, Chung O. Lee, Jung-Tae Lee, Hong-Moon Jung, Tae-Geon Kwon   +4 more
doaj   +1 more source