Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
Genotypic and Phenotypic Characterization of Seven Individuals With Predicted Bone Morphogenetic Protein 2 (BMP2) Haploinsufficiency. [PDF]
Stavrén-Eriksson E +5 more
europepmc +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
A Narrative Review on Recombinant Human Bone Morphogenetic Protein 2: Where Are We Now? [PDF]
Von Benecke JP +5 more
europepmc +1 more source
Understanding Exosomes in Hair Regeneration
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad +3 more
wiley +1 more source
mRNA encoding bone morphogenetic protein-2 facilitated peri-implant bone formation of titanium implants placed in rat femurs. [PDF]
Jriyasetapong K +6 more
europepmc +1 more source
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 in Socket Preservation: A Randomized Controlled Clinical and Sequential Human Histological Trial (BMP-2 TRIAL). [PDF]
Reddy SSP +7 more
europepmc +1 more source
Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen +2 more
wiley +1 more source
RETRACTION: Effect of Encapsulation or Grafting on Release Kinetics of Recombinant Human Bone Morphogenetic Protein-2 from Self-Assembled Poly(Lactide-co-Glycolide Ethylene Oxide Fumarate) Nanoparticles. [PDF]
europepmc +1 more source

