Results 21 to 30 of about 79,226 (304)

Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells

Journal of Tissue Engineering, 2012
The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau, Mimmi Patrikoski, Miia Juntunen, Kasperi Kujala, Minna Kääriäinen, Hannu Kuokkanen, George K Sándor, Outi Vapaavuori, Riitta Suuronen, Bettina Mannerström, Brigitte von Rechenberg, Susanna Miettinen   +11 more
doaj   +1 more source

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

An osteoinductive and biodegradable intramedullary implant accelerates bone healing and mitigates complications of bone transport in male rats

Nature Communications, 2023
Bone transport is a surgery-driven procedure for the treatment of large bone defects. However, challenging complications include prolonged consolidation, docking site nonunion and pin tract infection.
Sien Lin, Hirotsugu Maekawa, Seyedsina Moeinzadeh, Elaine Lui, Hossein Vahid Alizadeh, Jiannan Li, Sungwoo Kim, Michael Poland, Benjamin C. Gadomski, Jeremiah T. Easley, Jeffrey Young, Michael Gardner, David Mohler, William J. Maloney, Yunzhi Peter Yang   +14 more
doaj   +1 more source

Bone Morphogenetic Protein 1 Prodomain Specifically Binds and Regulates Signaling by Bone Morphogenetic Proteins 2 and 4 [PDF]

Journal of Biological Chemistry, 2007
Highly purified fractions of bone extracts capable of inducing ectopic bone formation have been reported to contain peptides corresponding to the mature active regions of the TGF-beta-like bone morphogenetic proteins (BMPs) 2-7, and to the prodomain region of the metalloproteinase BMP1.
Reema, Jasuja, Gaoxiang, Ge, Nikolas G, Voss, Jamie, Lyman-Gingerich, Amanda M, Branam, Francisco J, Pelegri, Daniel S, Greenspan   +6 more
openaire   +2 more sources

Sustained Release of Bone Morphogenetic Protein 2 via Coacervate

Foot & Ankle Orthopaedics, 2016
Category: Basic Sciences/Biologics Introduction/Purpose: Currently, there is no cure for osteoarthritis (OA) with treatment aimed at symptom relief and improved function.
MaCalus V. Hogan MD, Justin H. Hicks, Biomedical Engineering, Jorge L. Rocha BA, Hongshuai Li MD, PhD, Yadong Wang, Johnny Huard   +6 more
doaj   +1 more source

Kielin/chordin‐like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein‐2

FEBS Open Bio, 2023
Bone morphogenetic proteins (BMPs) play a key role in embryonic differentiation for osteoblast and bone formation. Kielin/chordin‐like protein (Kcp) is known to enhance the effects of BMP signaling.
Kei Nagasaki, Atsushi Yamada, Kiyohito Sasa, Ryutaro Kamijo   +3 more
doaj   +1 more source

The effect of bone morphogenetic protein-2 on osteosarcoma metastasis. [PDF]

PLoS ONE, 2017
PURPOSE:Bone Morphogenetic Protein-2 (BMP-2) may offer the potential to enhance allograft-host osseous union in limb-salvage surgery following osteosarcoma resection.
Jonathan Gill, Patrick Connolly, Michael Roth, So Hak Chung, Wendong Zhang, Sajida Piperdi, Bang Hoang, Rui Yang, Hillary Guzik, Jonathan Morris, Richard Gorlick, David S Geller   +11 more
doaj   +1 more source

BMP4 Induces Cardiomyocyte Hypertrophy Through the Activation of ERK 1/2 Signaling Pathway in H9c2 Cells [PDF]

Brazilian Archives of Biology and Technology
Bone morphogenetic protein-4 (BMP4) is a member of the bone morphogenetic protein family which plays an important role in bone formation, inflammation and cardiac hypertrophy.
Yu Yuan, Yezheng Tao, Yongzhi Deng, Qunhui Ye, Bin Lin, Lin Wu   +5 more
doaj   +2 more sources

Development, In-Vitro Characterization and In-Vivo Osteoinductive Efficacy of a Novel Biomimetically-Precipitated Nanocrystalline Calcium Phosphate With Internally-Incorporated Bone Morphogenetic Protein-2

Frontiers in Bioengineering and Biotechnology, 2022
The repair of large-volume bone defects (LVBDs) remains a great challenge in the fields of orthopedics and maxillofacial surgery. Most clinically available bone-defect-filling materials lack proper degradability and efficient osteoinductivity.
Gaoli Xu, Gaoli Xu, Chenxi Shen, Chenxi Shen, Haiyan Lin, Haiyan Lin, Jian Zhou, Ting Wang, Ben Wan, Ben Wan, Munerah Binshabaib, Tymour Forouzanfar, Guochao Xu, Nawal Alharbi, Gang Wu, Gang Wu   +15 more
doaj   +1 more source

Preparation of Recombinant Bone Morphogenetic Protein 2 at Laboratory Scale

Regeneration, Reconstruction & Restoration, 2016
Introduction: Millions cases of bone fracture are reported annually worldwide. The conventional methods for the repair often fail. The complications of using routine methods include stimulation of bone repair which should be performed without infection ...
Mahmoud Kazemi, Ali Hassani, Mojgan Bandehpour, Bahram Kazemi   +3 more
doaj   +1 more source