Results 91 to 100 of about 183,822 (327)

Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

open access: yesEndocrine Regulations, 2019
Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia.
Malekmohamadi Nasim   +6 more
doaj   +1 more source

The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans

open access: yesDiabetes, 2012
Overweight characterized by inappropriate expansion of adipose cells (hypertrophic obesity) is associated with the metabolic syndrome and is caused by an inability to recruit and differentiate new precursor cells.
B. Gustafson, U. Smith
semanticscholar   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

The effects of various bone replacement materials on bone regeneration in rats

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
The aim of this study was to compare the effects of autogeneous and allogeneous grafts to the effects of BMP (Bone morphogenetic protein) and hydroxyapatite (pyrost), which induce osteogenesis on bone regeneration.
Harzem Ozger   +3 more
doaj  

Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]

open access: yes, 2016
Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core  

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth [PDF]

open access: yes, 2017
Bone morphogenetic proteins (Bmp) are well-known to induce bone formation following chondrogenesis, but the direct role of Bmp signaling in the osteoblast lineage is not completely understood.
Bellido, Teresita   +5 more
core   +3 more sources

Colocalization of Noggin and Bone Morphogenetic Protein-4 During Fracture Healing [PDF]

open access: yesJournal of Bone and Mineral Research, 2001
Abstract The regulation of callus formation during fracture repair involves the coordinate expression of growth factors and their receptors. This article describes the temporal and spatial expression of noggin gene, an antagonist to bone morphogenetic protein (BMP), during the fracture repair process.
Y, Yoshimura   +5 more
openaire   +2 more sources

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto   +6 more
wiley   +1 more source

Biological Behavior of Bioactive Glasses SinGlass (45S5) and SinGlass High (F18) in the Repair of Critical Bone Defects

open access: yesBiomolecules
This study evaluated the osteogenic potential of the bioactive glasses SinGlass (45S5) and SinGlass High (F18) in regenerating critical bone defects in rat calvaria.
Dayane Maria Braz Nogueira   +11 more
doaj   +1 more source

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