Results 71 to 80 of about 88,042,096 (284)

Bone Morphogenetic Protein-2 (BMP-2) and Vascular Endothelial Growth Factor (VEGF) Transfection to Human Periosteal Cells Enhances Osteoblast Differentiation and Bone Formation

Journal of Pharmacological Sciences, 2008
Periosteum has been demonstrated to contain mesenchymal progenitor cells differentiating to osteoblasts, and both bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) may play important roles in cell-based approaches to bone
Mayurach Samee, Shohei Kasugai, Hisatomo Kondo, Keiichi Ohya, Hitoyata Shimokawa, Shinji Kuroda   +5 more
doaj   +1 more source

The role of bone morphogenetic protein 4 in inner ear development and function [PDF]

Hearing Research, 2007
Bone Morphogenetic Protein 4 (BMP4) is a member of the TGF-beta superfamily and is known to be important for the normal development of many tissues and organs, including the inner ear. Bmp4 homozygous null mice die as embryos, but Bmp4 heterozygous null (Bmp4(+/-)) mice are viable and some adults exhibit a circling phenotype, suggestive of an inner ear
Marsha N, Blauwkamp, Lisa A, Beyer, Lisa, Kabara, Keiji, Takemura, Timothy, Buck, W M, King, David F, Dolan, Kate F, Barald, Yehoash, Raphael, Ronald J, Koenig   +9 more
openaire   +2 more sources

Growth hormone induces bone morphogenetic proteins and bone-related proteins in the developing rat periodontium

, 2001
The hypothesis that growth hormone (GH) up-regulates the expression of enzymes, matrix proteins, and differentiation markers involved in mineralization of tooth and bone matrices was tested by the treatment of Lewis dwarf rats with GH over 5 days.
Bartold, P. Mark, P. Mark Bartold, Huika Li, Waters, M., Xiao, Y., Young, William G., Li, Huika, Xiao, Yin, Waters, Michael John, Michael J. Waters, Bartold, P., Young, W., Yin Xiao, Li, H., William G. Young   +14 more
core   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Molecular docking of polyether ether ketone and nano-hydroxyapatite as biomaterial candidates for orthodontic mini-implant fabrication. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2022
Context: Modified polyether ether ketone (PEEK) by adding nano-hydroxyapatite (HA) material on its fixture for mini-implant fabrication may increase resistance force through osseointegration.
I Gusti Aju Wahju Ardani, Alexander Patera Nugraha, Monika Nilam Suryani, Ryan Hafidz Putra Pamungkas, Devani Githa Vitamamy, Rizky Alif Susanto, Riyanarto Sarno, Aziz Fajar, Viol Dhea Kharisma, Albertus Putera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor   +10 more
doaj  

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain

Molecular Pain, 2019
Background Bone morphogenetic protein-2/4 (BMP2/4) has been recognized as promoters of astrocyte activity. Substantial evidence suggests that BMP2/4 may be elevated and plays a critical role in astrocyte activation upon spinal cord injury.
Lin Yang, Shuxin Liu, Yaping Wang
doaj   +1 more source

The risk of tumor with the use of recombinant human bone morphogenetic proteins

Гений oртопедии, 2022
Introduction Bone morphogenetic proteins (BMPs) are members of a large family of growth factors known as the transforming growth factor-β (TGF-β) superfamily. BMPs are known for their ability to induce bone formation and successfully used in orthopaedic
Ural F. Mukhametov, Sergey V. Lyulin, Dmitry Yu. Borzunov, Rinat A. Sufianov, Ilgiz F. Gareev   +4 more
doaj   +1 more source

Colocalization of Noggin and Bone Morphogenetic Protein-4 During Fracture Healing [PDF]

Journal of Bone and Mineral Research, 2001
Abstract The regulation of callus formation during fracture repair involves the coordinate expression of growth factors and their receptors. This article describes the temporal and spatial expression of noggin gene, an antagonist to bone morphogenetic protein (BMP), during the fracture repair process.
Y, Yoshimura, S, Nomura, S, Kawasaki, T, Tsutsumimoto, T, Shimizu, K, Takaoka   +5 more
openaire   +2 more sources

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source