Results 21 to 30 of about 2,650,892 (412)
Significance of mechanical loading in bone fracture healing, bone regeneration, and vascularization
Journal of Tissue Engineering, 2023 In 1892, J.L. Wolff proposed that bone could respond to mechanical and biophysical stimuli as a dynamic organ. This theory presents a unique opportunity for investigations on bone and its potential to aid in tissue repair.
Qianli Ma +4 more
semanticscholar +1 more source
Advanced Functional Materials, 2023 The treatment of irregular bone defects remains a clinical challenge since the current biomaterials (e.g., calcium phosphate bone cement (CPC)) mainly act as inert substitutes, which are incapable of transforming into a regenerated host bone (termed ...
Yamin Li +12 more
semanticscholar +1 more source
Hydrogel Drug Delivery Systems for Bone Regeneration
Pharmaceutics, 2023 With the in-depth understanding of bone regeneration mechanisms and the development of bone tissue engineering, a variety of scaffold carrier materials with desirable physicochemical properties and biological functions have recently emerged in the field ...
Long Bai +6 more
semanticscholar +1 more source
Osteoimmunomodulatory Nanoparticles for Bone Regeneration
Nanomaterials, 2023 Treatment of large bone fractures remains a challenge for orthopedists. Bone regeneration is a complex process that includes skeletal cells such as osteoblasts, osteoclasts, and immune cells to regulate bone formation and resorption.
Jingyi Wen +8 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Guided bone regeneration (GBR) has become a clinically standard modality for the treatment of localized jawbone defects. Barrier membranes play an important role in this process by preventing soft tissue invasion outgoing from the mucosa and creating an ...
Yanru Ren +10 more
semanticscholar +1 more source
Spatiotemporal mapping of osteomyelitis pathogenesis guides the design of functionally graded bone regeneration scaffolds. [PDF]
Sci RepWang C +11 more
europepmc +2 more sources
Oral and Maxillofacial Surgery Clinics of North America, 2002 Currently, the use of guided bone regeneration in the fields of oral and maxillofacial surgery, periodontics, and plastic and reconstructive surgery is a predictable and effective technique to prevent epithelial and connective tissue migration into an osseous defect.
Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, University of Florida College of Dentistry, P.O. Box 100416, Gainesville, FL, USA ( host institution ) +3 more
openaire +3 more sources
Di-san junyi daxue xuebao, 2020 Objective To investigate the effect and underlying mechanism of activating Notch signaling in osteocytes on osteogenic differentiation of bone marrow stromal cells (BMSCs). Methods The osteocytes derived from RosaNotch mice were infected with recombinant
XIE Yingchun, TU Xiaolin
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: Aging and oxidative stress are considered to be the proximal culprits of postmenopausal osteoporosis. Eldecalcitol (ED-71), a new active vitamin D derivative, has shown a good therapeutic effect on different types of osteoporosis, but the ...
Yuying Kou +15 more
doaj +1 more source
Neurovascular coupling in bone regeneration
Experimental and Molecular Medicine, 2022 The mammalian skeletal system is densely innervated by both neural and vascular networks. Peripheral nerves in the skeleton include sensory and sympathetic nerves. The crosstalk between skeletal and neural tissues is critical for skeletal development and
Q. Qin +6 more
semanticscholar +1 more source