Results 21 to 30 of about 174,184 (273)
Medicina, 2023 Background and Objectives: The incidence of diabetic osteoporosis, an important complication of diabetes mellitus, is increasing gradually. This study investigated the combined effect of the Zuogui pill (ZGP) and eldecalcitol (ED-71), a novel vitamin D ...
Tuo Shi +8 more
doaj +1 more source
A high-glucose diet affects Achilles tendon healing in rats
Scientific Reports, 2017 Chronic and acute tendinopathies are difficult to treat and tendon healing is generally a very slow and incomplete process and our general understanding of tendon biology and regeneration lags behind that of muscle or bone.
Stefanie Korntner +10 more
doaj +1 more source
Synergistic effect of Si-hydroxyapatite coating and VEGF adsorption on Ti6Al4V-ELI scaffolds for bone regeneration in an osteoporotic bone environment [PDF]
Acta Biomaterialia. 83, 456-466 (2018), 2021 The osteogenic and angiogenic responses to metal macroporous scaffolds coated with silicon substituted hydroxyapatite (SiHA) and decorated with vascular endothelial growth factor (VEGF) have been evaluated in vitro and in vivo. Ti6Al4V-ELI scaffolds were prepared by electron beam melting and subsequently coated with Ca10(PO4)5.6(SiO4)0.4(OH)1.6 ...
arxiv +1 more source
Molecules, 2019 Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms.
Ziqi Yue +9 more
doaj +1 more source
JBJS Open Access, 2021 Background:. Treatment of massive acetabular defects, both with and without pelvic discontinuity, is challenging. The implants utilized in the surgical procedure need to be stable and integrate with poor host bone stock. In the present study, we describe
Vitali Goriainov, BM, FRCS(Orth), Msc, PhD +3 more
doaj +1 more source
Multifunctional pH sensitive 3D scaffolds for treatment and prevention of bone infection [PDF]
Acta Biomaterialia. 65, 450-461 (2018), 2021 Multifunctional-therapeutic 3D scaffolds have been prepared. These biomaterials are able to destroy the S. aureus bacteria biofilm and to allow bone regeneration at the same time. The present study is focused on the design of pH sensitive 3D hierarchical meso-macroporous scaffolds based on MGHA nanocomposite formed by a mesostructured glassy network ...
arxiv +1 more source
Cells, 2023 Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse pharmacotherapeutic properties due to their various functional groups being attached to a common core structure.
Victor Martin +4 more
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An $\textit{in vivo}$ comparison study between strontium nanoparticles and rhBMP2 [PDF]
Frontiers in Bioengineering and Biotechnology 2020;8:499, 2020 The osteoinductive property of strontium was repeatedly proven in the last decades. Compelling $\textit{in vitro}$ data demonstrated that strontium hydroxyapatite nanoparticles exert a dual action, by promoting osteoblasts-driven matrix secretion and inhibiting osteoclasts-driven matrix resorption. Recombinant human bone morphogenetic protein 2 (rhBMP2)
arxiv +1 more source
Cell Death Discovery, 2023 Peroxiredoxin 1 (Prdx1), a vital antioxidant enzyme, has been proven to play an important role in the occurrence and development of cancers, but its effects on oral squamous cell carcinoma (OSCC) remain unclear. Here, we performed bioinformatics analysis
Meilin Ye +7 more
doaj +1 more source
In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint
Biomedicines, 2021 Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics.
Lisa Sturm +10 more
doaj +1 more source