Results 41 to 50 of about 2,247,449 (357)

Ribosomopathies: New Therapeutic Perspectives

Cells, 2020
Ribosomopathies are a group of rare diseases in which genetic mutations cause defects in either ribosome biogenesis or function, given specific phenotypes.
Emilien Orgebin, François Lamoureux, Bertrand Isidor, Céline Charrier, Benjamin Ory, Frédéric Lézot, Marc Baud’huin   +6 more
doaj   +1 more source

Chitosan as a biomaterial for the prevention and treatment of dental caries: antibacterial effect, biomimetic mineralization, and drug delivery

Frontiers in Bioengineering and Biotechnology, 2023
Dental caries is a chronic, progressive disease caused by plaque, influenced by multiple factors and can damage the hard tissues of the teeth. In severe cases, it can also lead to the onset and development of other oral diseases, seriously affecting ...
Shanlin Qu, Shanlin Qu, Xiaolin Ma, Xiaolin Ma, Shuo Yu, Shuo Yu, Rui Wang, Rui Wang   +7 more
doaj   +1 more source

sLZIP functions as a key modulator of bone remodeling by regulating the crosstalk between osteoblasts and osteoclasts. [PDF]

Exp Mol Med
Park S, Kim J, Ko J.
europepmc   +3 more sources

The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

Cells, 2020
Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children, adolescents, and young adults, and with a second peak of incidence in elderly individuals.
Isabelle Corre, Franck Verrecchia, Vincent Crenn, Francoise Redini, Valérie Trichet   +4 more
doaj   +1 more source

Immunohistochemical Evaluation of Bone Remodeling Following Compressive Force on Mandibular Condyle. [PDF]

Biology (Basel)
Lyros I, Tsolakis IA, Kotantoula G, Tosios K, George V, Nikitakis N, Ferdianakis E, Lykogeorgos T, Fora E, Tsolakis AI.   +9 more
europepmc   +3 more sources

RANKL/RANK/OPG Pathway: A Mechanism Involved in Exercise-Induced Bone Remodeling

BioMed Research International, 2020
Bones as an alive organ consist of about 70% mineral and 30% organic component. About 200 million people are suffering from osteopenia and osteoporosis around the world.
Mohammad Tobeiha, M. Moghadasian, Negin Amin, S. Jafarnejad   +3 more
semanticscholar   +1 more source

Experimental study of dexamethasone-loaded hollow hydroxyapatite microspheres applied to direct pulp capping of rat molars

Frontiers in Endocrinology, 2023
BackgroundDexamethasone (DEX) exerts anti-inflammatory and osteogenic effects. Hydroxyapatite is commonly used in bone repair due to its osteoconductivity, osseointegration, and osteogenesis induction. Hollow hydroxyapatite (HHAM) is often used as a drug
Xiaoli Liu, Yuandong Xie, Weijia Gao, Luoning Zhan, Ling Hu, Linjing Zuo, Yi Li   +6 more
doaj   +1 more source

3D porous architecture of stacks of β-TCP granules compared with that of trabecular bone: a microCT, vector analysis and compression study

Frontiers in Endocrinology, 2015
The 3D arrangement of porous granular biomaterials usable to fill bone defects has received little study. Granular biomaterials occupy 3D space when packed together in a manner that creates a porosity suitable for the invasion of vascular and bone cells.
Daniel eCHAPPARD, Daniel eCHAPPARD, Lisa eTerranova, Romain eMallet, Romain eMallet, Philippe eMercier, Philippe eMercier   +6 more
doaj   +1 more source

Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]

, 2018
Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N., McNulty, Margaret A., Mitchell, Colin F., Richbourg, Heather A.   +3 more
core   +1 more source

Towards a New Spatial Representation of Bone Remodeling [PDF]

, 2012
Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.
Ayati, Bruce P., Graham, Jason M., Martin, James A., Ramakrishnan, Prem S.   +3 more
core   +2 more sources