Results 71 to 80 of about 2,247,449 (357)

D-methionine eradicates Porphyromonas gingivalis biofilms by suppressing the cyclic di-GMP level

口腔疾病防治, 2022
Objective To investigate the mechanisms by which D-methionine (D-Met) eradicates Porphyromonas gingivalis biofilms by suppressing cyclic dimeric GMP (c-di-GMP) levels.
XIE Lili, ZHANG Huiyan, WANG Zixuan, LI Birong, LI Zhen, MENG Weiyan   +5 more
doaj   +1 more source

Mineral maturity and crystallinity index are distinct characteristics of bone mineral [PDF]

, 2010
The purpose of this study was to test the hypothesis that mineral maturity and crystallinity index are two different characteristics of bone mineral. To this end, Fourier transform infrared microspectroscopy (FTIRM) was used.
A Boskey, A Carden, A Carden, A Gee, A Shemesh, AB Barry, AC Ferrari, AL Boskey, AL Boskey, AL Boskey, AS Posner, B Giri, C Jager, C Rey, C Rey, C Rey, C Rey, CH Turner, CH Turner, CH Turner, Christian Rey, CP Tarnowski, D Chachra, D Faibish, Delphine Farlay, E Durchschlag, E Fitzer EG, E Pucéat, EP Paschalis, EP Paschalis, EP Paschalis, EP Paschalis, G Boivin, Georges Boivin, Gérard Panczer, J Green, JD Termine, JS Yerramshetty, JW Ager, KL Dziak, L Nasdala, LM Miller, LM Miller, LM Miller, MD Grynpas, MD Morris, MG Glimcher, N Pleshko, NP Camacho, O Akkus, O Akkus, P Fratzl, P Fratzl, PD Frazier, Pierre D. Delmas, RG Hanschin, RY Huang, RZ Legeros, S Bang, S Bohic, S Cazalbou, S Tadano, SJ Gadaleta, WJ Landis, Y Li   +64 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation

Journal of Nanobiotechnology
Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and programmed
Jiaxin Luo, Jingxia Chen, Jing Zhou, Zhen Ci, Jian Feng, Xuyan Wei, Jingjie Zhai, Hanchi Wang, Yanmin Zhou   +8 more
doaj   +1 more source

Mechanoregulation of bone remodeling and healing as inspiration for self-repair in materials

, 2019
The material bone has attracted the attention of material scientists due to its fracture resistance and ability to self-repair. A mechanoregulated exchange of damaged bone using newly synthesized material avoids the accumulation of fatigue damage.
Eberl, C., Fratzl, P., Weinkamer, R.
core   +1 more source

Oxidative stress in bone remodeling: role of antioxidants.

CLINICAL CASES IN MINERAL AND BONE METABOLISM, 2017
ROS are highly reactive molecules which consist of a number of diverse chemical species, including radical and non-radical oxygen species. Oxidative stress occurs as a result of an overproduction of ROS not balanced by an adequate level of antioxidants ...
Vladana Domazetovic, G. Marcucci, T. Iantomasi, M. Brandi, M. Vincenzini   +4 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Gallium and gallium compounds: New insights into the “Trojan horse” strategy in medical applications

Materials & Design, 2023
Infection, inflammation, tumors, and other illnesses have for a long time posed a major danger to human health and have developed into a global public health issue.
Wenyue Sun, Manlin Qi, Shi Cheng, Chunyan Li, Biao Dong, Lin Wang   +5 more
doaj   +1 more source

Exenatide Improves Bone Quality in a Murine Model of Genetically Inherited Type 2 Diabetes Mellitus [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) is associated with skeletal complications, including an increased risk of fractures. Reduced blood supply and bone strength may contribute to this skeletal fragility.
Andreozzi, Anetzberger, Anichini, Aoyama, Baggio, Balint, Ban, Beckman, Bouxsein, Brunton, Chen, Coleman, Dempster, Ealey, Eckel, Feng, Flatt, Friedman, Griffith, Griffith, Hamilton, Hu, Karim, Kim, Lee, Lu, Ma, Mabilleau, Mabilleau, Mansur, Marenzana, Mieczkowska, Napoli, Nuche-Berenguer, Nuche-Berenguer, Nuche-Berenguer, Nystrom, Nystrom, Odgaard, Okerson, Orland, Orriss, Paschalis, Pereira, Pereira, Prisby, Richard, Roche, Roszer, Schalkwijk, Scheller, Selley, Shymkiw, Smits, Stabley, Sun, Tartaglia, Upadhyay, van Bloemendaal, Vijan, Williams, Wu, Yamamoto, Yamamoto, Yamamoto   +64 more
core   +5 more sources