Results 71 to 80 of about 356,262 (352)
Stable fixation of an osseointegated implant system for above-the-knee amputees: titel RSA and radiographic evaluation of migration and bone remodeling in 55 cases. [PDF]
, 2012 Background and purposeRehabilitation of patients with transfemoral amputations is particularly difficult due to problems in using standard socket prostheses.
Antonellis, Anne +5 more
core +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Porphyromonas gingivalis lipopolysaccharide affects oral epithelial connections via pyroptosis
Journal of Dental Sciences, 2021 Background/purpose: Pyroptosis is a form of programmed cell death dependent on the activation of caspase-1. Porphyromonas gingivalis (P. gingivalis) is a major pathogenic bacterium in periodontitis and its lipopolysaccharide (LPS) can trigger ...
Yuyang Li +7 more
doaj +1 more source
STRUCTURAL ANALYSIS DRIVEN SHOULDER ARTHROPLASTY [PDF]
, 2007 Shoulder arthroplasty, the most common treatment option for patients diagnosed with end-stage glenohumeral osteoarthritis, is able to provide pain relief and restore some functionality.
Sharma, Gulshan Baldev
core
Role of SPARC in Bone Remodeling and Cancer‐Related Bone Metastasis [PDF]
, 2013 There is a growing socioeconomic recognition that clinical bone diseases such as bone infections, bone tumors and osteoporotic bone loss mainly associated with ageing, are major issues in today0s society.
Brekken, Rolf A. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Interactions between remodelling, architecture and tissue properties in cancellous bone [PDF]
, 2003 The aim of the research projects described in this thesis was to gain more insight in the regulation of bone remodeling and in the interactions between bone remodeling, architecture and bone tissue properties.
Linden, J.C. (Jacqueline) van der
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Materials for Biomedical Applications [PDF]
, 1998 This paper discusses two ceramic material systems for selective laser sintering (SLS) that are being developed for biomedical applications for use in repair of bone defects.
Aufdemorte, T. B. +5 more
core +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source