Results 81 to 90 of about 2,011,561 (382)

Retinoid Receptors in Bone and Their Role in Bone Remodeling [PDF]

Frontiers in Endocrinology, 2015
Vitamin A (retinol) is a necessary and important constituent of the body which is provided by food intake of retinyl esters and carotenoids. Vitamin A is known best for being important for vision, but in addition to the eye, vitamin A is necessary in numerous other organs in the body, including the skeleton. Vitamin A is converted to an active compound,
Petra eHenning, Howard Herschel Conaway, Ulf Holger Lerner, Ulf Holger Lerner   +3 more
openaire   +5 more sources

Identification of cross-talk pathways and PANoptosis-related genes in periodontitis and Alzheimer’s disease by bioinformatics analysis and machine learning

Frontiers in Aging Neuroscience
Background and objectivesPeriodontitis (PD), a chronic inflammatory disease, is a serious threat to oral health and is one of the risk factors for Alzheimer’s disease (AD).
Xiantao Chen, Xiantao Chen, Yifei Dai, Yifei Dai, Yushen Li, Yushen Li, Jiajun Xin, Jiajun Xin, Jiatong Zou, Jiatong Zou, Rui Wang, Rui Wang, Hao Zhang, Hao Zhang, Zhihui Liu, Zhihui Liu   +15 more
doaj   +1 more source

New strategy of personalized tissue regeneration: when autologous platelet concentrates encounter biomaterials

Frontiers in Bioengineering and Biotechnology, 2023
Components in blood play an important role in wound healing and subsequent tissue regeneration processes. The fibrin matrix and various bioactive molecules work together to participate in this complex yet vital biological process.
Sicong Ren, Sicong Ren, Hanchi Wang, Hanchi Wang, Sijia Ma, Jing Zhou, Jingjie Zhai, Yuemeng Zhu, Yuemeng Zhu, Sheng Chen, Sheng Chen, Siyu Chen, Siyu Chen, Kewen Jia, Kewen Jia, Wenzhou Xu, Yanmin Zhou   +16 more
doaj   +1 more source

Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism

Scientific Reports, 2019
Mounting evidence from animal studies suggests a role of the nervous system in bone physiology. However, little is known about the nerve fiber localization to human bone compartments and bone surface events.
Manasi Sayilekshmy, R. B. Hansen, J. Delaissé, L. Rolighed, T. L. Andersen, A. Heegaard   +5 more
semanticscholar   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing

Frontiers in Bioengineering and Biotechnology, 2020
The healing of bone fractures is a well-orchestrated physiological process involving multiple cell types and signaling molecules interacting at the fracture site to replace and repair bone tissue without scar formation.
Luciano Vidal, Carina Kampleitner, Meadhbh Á. Brennan, Meadhbh Á. Brennan, Alain Hoornaert, Alain Hoornaert, Pierre Layrolle   +6 more
doaj   +1 more source

The Role of Exosomes in Bone Remodeling: Implications for Bone Physiology and Disease

Disease Markers, 2019
Bone remodeling represents a physiological phenomenon of continuous bone tissue renewal that requires fine orchestration of multiple cell types, which is critical for the understanding of bone disease but not yet clarified in precise detail.
C. Masaoutis, S. Theocharis
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

The effects of nano-silver loaded zirconium phosphate on antibacterial properties, mechanical properties and biosafety of room temperature curing PMMA materials

Frontiers in Cellular and Infection Microbiology, 2023
Polymethyl methacrylate (PMMA) frequently features in dental restorative materials due to its favorable properties. However, its surface exhibits a propensity for bacterial colonization, and the material can fracture under masticatory pressure.
Xingjian Chen, Tongtong Yan, Tongtong Yan, Shiqun Sun, Aoke Li, Aoke Li, Xiaorong Wang, Xiaorong Wang   +7 more
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source