Results 11 to 20 of about 641,029 (315)

Predicting Angiogenesis by Endothelial Progenitor Cells Relying on In-Vitro Function Assays and VEGFR-2 Expression Levels

Biomolecules, 2019
Clinical trials have demonstrated the safety and efficacy of autologous endothelial progenitor cell (EPC) therapy in various diseases. Since EPCs’ functions are influenced by genetic, systemic and environmental factors, the therapeutic potential of
Nadin Sabbah, Tal Tamari, Rina Elimelech, Ofri Doppelt, Utai Rudich, Hadar Zigdon-Giladi   +5 more
doaj   +1 more source

Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists. [PDF]

, 2016
UnlabelledAlthough adipose-derived stem cells (ASCs) are an attractive cell source for bone tissue engineering, direct use of ASCs alone has had limited success in the treatment of large bone defects.
Aghaloo, Tara L, Bezouglaia, Olga, Cui, Zhong-Kai, Fan, Jiabing, Fartash, Armita, Guo, Mian, Im, Choong Sung, Kim, Soyon, Lee, Min, Patel, Nikhil, Wang, Cun-Yu, Wu, Benjamin M   +11 more
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Bardoxolone methyl ameliorates osteoarthritis by inhibiting osteoclastogenesis and protecting the extracellular matrix against degradation

Heliyon, 2023
Inflammation and oxidative damage are closely related to the development of osteoarthritis. Bardoxolone methyl (CDDO-Me), a semisynthetic oleanane triterpenoid, plays a strong anti-inflammatory and antioxidant role.
Ruijia Yang, Yanjing Guo, Sujing Zong, Zhou Ma, Zhenyu Wang, Jiyu Zhao, Jinmei Yang, Liping Li, Chongwei Chen, Shaowei Wang   +9 more
doaj   +1 more source

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Mijiritsky, Eitan, Piattelli, Adriano, Zanette, Gastone, Zavan, Barbara   +6 more
core   +2 more sources

Bioactive SrO-SiO2 glass with well-ordered mesopores: Characterization, physiochemistry and biological properties [PDF]

, 2011
For a biomaterial to be considered suitable for bone repair it should ideally be both bioactive and have a capacity for controllable drug delivery; as such, mesoporous SiO2 glass has been proposed as a new class of bone regeneration material by virtue of
Cuniberti, Gianaurelio, Doert, Thomas, Fan, Wei, Gelinsky, Michael, Luo, Yongxiang, Schulze, Renate, Simon, Paul, Wu, Chengtie, Xiao, Yin   +8 more
core   +2 more sources

Combination of chondrocytes and chondrons improves extracellular matrix production to promote the repairs of defective knee cartilage in rabbits

Journal of Orthopaedic Translation, 2021
Background: Chondrons are composed of chondrocytes and the surrounding pericellular matrix (PCM) and function to enhance chondrocyte-mediated cartilage tissue engineering.
Wangping Duan, Yu Zhao, Xiaochun Ren, Ruipeng Zhao, Qi Li, Zhenwei Sun, Wenjie Song, Yanfei Yang, Pengcui Li, Xiaochun Wei   +9 more
doaj   +1 more source

Inflammation, fracture and bone repair [PDF]

Bone, 2016
The reconstitution of lost bone is a subject that is germane to many orthopedic conditions including fractures and non-unions, infection, inflammatory arthritis, osteoporosis, osteonecrosis, metabolic bone disease, tumors, and periprosthetic particle-associated osteolysis. In this regard, the processes of acute and chronic inflammation play an integral
Loi, Florence, Córdova Jara, Luis, Pajarinen, Jukka, Lin, Tzu-hua, Yao, Zhenyu, Goodman, Stuart B.   +5 more
openaire   +3 more sources

The association between three-dimensional measurement of posterior tilt angle in impacted femoral neck fractures and osteonecrosis of the femoral head

BMC Musculoskeletal Disorders, 2023
Background Hollow screw internal fixation is commonly used in clinical treatment of impacted femoral neck fractures. Previous studies have demonstrated a correlation between the preoperative posterior tilt angle of the femoral head and failure of ...
Bo Cong, Haiguang Zhang
doaj   +1 more source

Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database

BMJ Open, 2022
Objective To explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.Design A cross-sectional study.Setting National Health and Nutrition Examination Surveys database.Participants 12 576 patients.Primary ...
Lin Chen, Yangli Xie, Zheng Zheng, Junlan Huang, Xianding Sun, Ruobin Zhang   +5 more
doaj   +1 more source

Oral fibroblasts rescue osteogenic differentiation of mesenchymal stem cells after exposure to Zoledronic acid in a paracrine effect

Frontiers in Pharmacology, 2023
Background: Medication-related osteonecrosis of the jaw is a serious complication that develops in oncologic patients treated with Zoledronic acid. Although used for over 30 years, the influence of Zoledronic acid on bone has been thoroughly investigated,
Tal Berg, Tal Berg, Ofri Doppelt-Flikshtain, Ofri Doppelt-Flikshtain, Benjamin R. Coyac, Benjamin R. Coyac, Hadar Zigdon-Giladi, Hadar Zigdon-Giladi, Hadar Zigdon-Giladi   +8 more
doaj   +1 more source