Results 11 to 20 of about 14,966 (263)

Bone resorption: supporting immunometabolism [PDF]

Biology Letters, 2018
Activation of the immune system is associated with an increase in the breakdown of various peripheral tissues, including bone. Despite the widely appreciated role of inflammatory mediators in promoting bone resorption, the functional value behind this process is not completely understood.
Gustav van Niekerk, Megan Mitchell, Anna-Mart Engelbrecht   +2 more
openaire   +2 more sources

Current Topics in Pharmacological Research on Bone Metabolism: Regulation of Bone Mass by the Function of Endogenous Modulators of Bone Morphogenetic Protein in Adult Stage

Journal of Pharmacological Sciences, 2006
.: Bone formation in adults determines the basic mass of bone and hence it is crucial to understand the mechanisms of its regulation. As remodeling is proceeding, bone resorption is determined by the physical conditions.
Masaki Noda
doaj   +1 more source

Nanotechnology and Dental Implants

International Journal of Biomaterials, 2010
The long-term clinical success of dental implants is related to their early osseointegration. This paper reviews the different steps of the interactions between biological fluids, cells, tissues, and surfaces of implants.
Sandrine Lavenus, Guy Louarn, Pierre Layrolle   +2 more
doaj   +1 more source

The Role of Calcium in Inflammation-Associated Bone Resorption

Biomolecules, 2018
The aim of this mini-review is to discuss the role of calcium in the process of cytokine-mediated bone resorption in an effort to understand the role circulating calcium may play in the resorption of bone.
Gordon L. Klein
doaj   +1 more source

Finite Element Analysis of Bone Resorption Around Dental Implant

Journal of Biomechanical Science and Engineering, 2009
Previously, a few models have been proposed to predict bone resorption process due to stress shielding in long bones such as proximal femur; however, there are almost no reports on finite element analysis of loss of marginal dental bone that is caused ...
Lihe QIAN, Mitsugu TODO, Yasuyuki MATSUSHITA, Kiyoshi KOYANO   +3 more
doaj   +1 more source

Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats

BMC Musculoskeletal Disorders, 2002
Background Avascular necrosis of bone (osteonecrosis) can cause structural failure and subsequent deformation, leading to joint dysfunction and pain. Structural failure is the result of resorption of necrotic bone during revascularization, before new ...
Aspenberg Per, Åstrand Jörgen
doaj   +1 more source

Sympathetic Innervation Regulates Osteocyte‐Mediated Cortical Bone Resorption during Lactation

Advanced Science, 2023
Bone undergoes constant remodeling by osteoclast bone resorption coupled with osteoblast bone formation at the bone surface. A third major cell type in the bone is osteocytes, which are embedded in the matrix, are well‐connected to the lacunar network ...
Qiaoyue Guo, Ningrong Chen, Cheng Qian, Cheng Qi, Kathleen Noller, Mei Wan, Xiaonan Liu, Weixin Zhang, Patrick Cahan, Xu Cao   +9 more
doaj   +1 more source

Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption

eLife, 2021
Bone formation and resorption are typically coupled, such that the efficacy of anabolic osteoporosis treatments may be limited by bone destruction. The multi-kinase inhibitor YKL-05–099 potently inhibits salt inducible kinases (SIKs) and may represent a ...
Cheng-Chia Tang, Christian D Castro Andrade, Maureen J O'Meara, Sung-Hee Yoon, Tadatoshi Sato, Daniel J Brooks, Mary L Bouxsein, Janaina da Silva Martins, Jinhua Wang, Nathanael S Gray, Barbara Misof, Paul Roschger, Stephane Blouin, Klaus Klaushofer, Annegreet Velduis-Vlug, Yosta Vegting, Clifford J Rosen, Daniel O'Connell, Thomas B Sundberg, Ramnik J Xavier, Peter Ung, Avner Schlessinger, Henry M Kronenberg, Rebecca Berdeaux, Marc Foretz, Marc N Wein   +25 more
doaj   +1 more source

Factors associated with implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis [PDF]

Xin yixue
Objective To analyze the factors related to implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis. Methods One hundred and ninety-five elderly patients with severe periodontitis who underwent implant ...
LI Yue, MA Yanru
doaj   +1 more source

Repair of microdamage in osteonal cortical bone adjacent to bone screw.

PLoS ONE, 2014
Up to date, little is known about the repair mode of microdamage in osteonal cortical bone resulting from bone screw implantation. In this study, self-tapping titanium cortical bone screws were inserted into the tibial diaphyses of 24 adult male rabbits.
Lei Wang, Tingjun Ye, Lianfu Deng, Jin Shao, Jin Qi, Qi Zhou, Li Wei, Shijing Qiu   +7 more
doaj   +1 more source