Results 11 to 20 of about 1,831,965 (356)

Autophagy Regulator Rufy 4 Promotes Osteoclastic Bone Resorption by Orchestrating Cytoskeletal Organization via Its RUN Domain [PDF]

open access: yesCells
Rufy4, a protein belonging to the RUN and FYVE domain-containing protein family, participates in various cellular processes such as autophagy and intracellular trafficking. However, its role in osteoclast-mediated bone resorption remains uncertain.
Eiko Sakai   +6 more
doaj   +2 more sources

Relationship between the Height of Alveolar Bone Resorption and Sex and Age in Adolescents

open access: yesFayixue Zazhi, 2022
ObjectiveTo explore the relationship between the height of alveolar bone resorption and sex and age in the adolescent dentition.MethodsMulti-slice computed tomography (MSCT) was used to measure the height of alveolar bone resorption at labial, lingual ...
MA Jing-jing   +7 more
doaj   +1 more source

Ammonia-induced Calcium Phosphate Nanostructure: A Potential Assay for Studying Osteoporosis and Bone Metastasis [PDF]

open access: yesACS Applied Materials & Interfaces Manuscript ID: am-2021-004953.R2, 2021
Osteoclastic resorption of bone plays a central role in both osteoporosis and bone metastasis. A reliable in vitro assay that simulates osteoclastic resorption in vivo would significantly speed up the process of devel-oping effective therapeutic solutions for those diseases. Here we reported the development of a novel and robust nano-structured calcium
arxiv   +1 more source

Adaptive bone-remodeling theory applied to prosthetic-design analysis [PDF]

open access: yes, 1987
The subject of this article is the development and application of computer-simulation methods to predict stress-related adaptive bone remodeling, in accordance with ‘Wolff's Law’.
Dalstra, M.   +5 more
core   +11 more sources

The Mechanism Switching the Osteoclast From Short to Long Duration Bone Resorption

open access: yesFrontiers in Cell and Developmental Biology, 2021
The current models of osteoclastic bone resorption focus on immobile osteoclasts sitting on the bone surface and drilling a pit into the bone matrix.
Jean-Marie Delaisse   +11 more
doaj   +1 more source

Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption

open access: yesInternational Journal of Molecular Sciences, 2020
The process of bone remodeling is the result of the regulated balance between bone cell populations, namely bone-forming osteoblasts, bone-resorbing osteoclasts, and the osteocyte, the mechanosensory cell type.
H. Kitaura   +9 more
semanticscholar   +1 more source

Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases

open access: yesScience Translational Medicine, 2020
Independent of cathepsin K, the osteoclast-derived matrix metalloproteinases MMP9 and MMP14 codependently drive bone resorption. Codependent deconstruction Bone homeostasis encompasses a balancing act between formation of new bone and remodeling and ...
Lingxin Zhu   +7 more
semanticscholar   +1 more source

Random walk models for the propagation of signalling molecules in one-dimensional spatial networks and their continuum limit [PDF]

open access: yesProc Roy Soc A (2024) 480: 20230906, 2023
The propagation of signalling molecules within cellular networks is affected by network topology, but also by the spatial arrangement of cells in the networks. Understanding the collective reaction--diffusion behaviour in space of signals propagating through cellular networks is an important consideration for example for regenerative signals that ...
arxiv   +1 more source

Bone Resorption Stimulation

open access: yesDefinitions, 2020
Bone Resorption Stimulation involves initiation of absorption and removal of the hard connective tissue that constitutes the vertebrate skeleton and consists of a matrix of collagenous fibers impregnated chiefly with calcium phosphate and calcium ...

semanticscholar   +1 more source

Effects of a mesoporous bioactive glass on osteoblasts, osteoclasts and macrophages [PDF]

open access: yesJ. Colloid Interface Sci. 528, 309-320 (2018), 2021
A mesoporous bioactive glass (MBG) of molar composition 75SiO2-20CaO-5P2O5 (MBG-75S) has been synthetized as a potential bioceramic for bone regeneration purposes. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), nitrogen adsorption studies and transmission electron microscopy (TEM) demonstrated that MBG-75Spossess a highly ...
arxiv   +1 more source

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