Results 11 to 20 of about 1,937,511 (400)
Mechanisms of Bone Resorption in Periodontitis [PDF]
Journal of Immunology Research, 2015 Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the ...
Stefan A. Hienz +2 more
openaire +5 more sources
Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level. [PDF]
PLoS ONE, 2013 Bone is able to react to changing mechanical demands by adapting its internal microstructure through bone forming and resorbing cells. This process is called bone modeling and remodeling.
Friederike A Schulte +6 more
doaj +2 more sources
Hypoxic regulation of osteoclast differentiation and bone resorption activity
Hypoxia, 2015 Bone integrity is maintained throughout life via the homeostatic actions of bone cells, namely, osteoclasts, which resorb bone, and osteoblasts, which produce bone. Disruption of this balance in favor of osteoclast activation results in pathological bone
Helen J. Knowles
openalex +3 more sources
Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling
Bone Research, 2021 Bone remodeling is precisely coordinated by bone resorption and formation. Apoptotic osteoclasts generate large amounts of apoptotic bodies (ABs) marking the end of the bone resorption phase, whereas the functions of osteoclast-derived ABs remain largely
Qinyu Ma +7 more
semanticscholar +1 more source
Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption
International Journal of Molecular Sciences, 2020 The process of bone remodeling is the result of the regulated balance between bone cell populations, namely bone-forming osteoblasts, bone-resorbing osteoclasts, and the osteocyte, the mechanosensory cell type.
H. Kitaura +9 more
semanticscholar +1 more source
Science Translational Medicine, 2020 Independent of cathepsin K, the osteoclast-derived matrix metalloproteinases MMP9 and MMP14 codependently drive bone resorption. Codependent deconstruction Bone homeostasis encompasses a balancing act between formation of new bone and remodeling and ...
Lingxin Zhu +7 more
semanticscholar +1 more source
Definitions, 2020 Bone Resorption Stimulation involves initiation of absorption and removal of the hard connective tissue that constitutes the vertebrate skeleton and consists of a matrix of collagenous fibers impregnated chiefly with calcium phosphate and calcium ...
semanticscholar +1 more source
Definitions, 2020 Bone Resorption Inhibition involves interference with, or restraint of, absorption and removal of the hard connective tissue that constitutes the vertebrate skeleton and consists of a matrix of collagenous fibers impregnated chiefly with calcium ...
semanticscholar +1 more source
Quantitative analysis of bone reactions to relative motions at implant-bone interfaces [PDF]
, 1993 Connective soft tissues at the interface between implants and bone, such as in human joint replacements, can endanger the stability of the implant fixation. The potential of an implant to generate interface bone resorption and form soft tissue depends on
Brunski +41 more
core +4 more sources
Effects of material properties of femoral hip components on bone remodeling [PDF]
, 1992 Bone loss around femoral hip stems is one of the problems threatening the long-term fixation of uncemented stems. Many believe that this phenomenon is caused by reduced stresses in the bone (stress shielding).
Grootenboer, H.J. +2 more
core +8 more sources