Results 191 to 200 of about 96,303 (248)

Longitudinal SARS-CoV-2 Antibody Response in Healthcare Workers: Benefit of Prior Infection and Heterologous Boosting on Anti-Spike IgG Immunity. [PDF]

Influenza Other Respir Viruses
Van Nedervelde E, Vancutsem E, De Geyter D, De Cock D, Buttiens R, Laeremans T, Aerts JL, Allard SD.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Socioeconomic Barriers to COVID-19 Booster Vaccination in Southern Italy: A Retrospective Study to Evaluate Association with the Social and Material Vulnerability Index in Apulia. [PDF]

Vaccines (Basel)
Bartolomeo N, Lorusso L, Maldera N, Trerotoli P.   +3 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A safe and efficacious inactivated vaccine aids prevent reproductive failure associated with congenital toxoplasmosis in ovine. [PDF]

Vet Res
Regidor-Cerrillo J, Largo-de la Torre A, Sánchez-Sánchez R, Ferre I, Moreno-Gonzalo J, Ortega-Mora LM.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intranasal DC-targeting vaccine booster elicits durable and cross-clade protective immunity against sarbecoviruses in mice. [PDF]

J Clin Invest
Cheang NYZ, Yap WC, Tullett KM, Qian X, Tan PS, Purushotorman K, Tan WY, Mah SYY, Macary PA, Tan CW, Lahoud MH, Alonso S.   +11 more
europepmc   +1 more source

Impact of cognitive training on claims-based diagnosed dementia over 20 years: evidence from the ACTIVE study. [PDF]

Alzheimers Dement (N Y)
Coe NB, Miller KEM, Sun C, Taggert E, Gross AL, Jones RN, Felix C, Albert MS, Rebok GW, Marsiske M, Ball KK, Willis SL.   +11 more
europepmc   +1 more source