Bordetella pertussis and Bordetella parapertussis: two immunologically distinct species [PDF]
Infection and Immunity, 1993 Bordetella pertussis and Bordetella parapertussis are closely related species. Both are responsible for outbreaks of whooping cough in humans and produce similar virulence factors, with the exception of pertussis toxin, specific to B. pertussis. Current pertussis whole-cell vaccine will soon be replaced by acellular vaccines containing major adhesins ...
N, Khelef +3 more
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The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]
PLoS ONE, 2012 Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj +1 more source
T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis. [PDF]
PLoS ONE, 2010 BACKGROUND: Despite the extensive use of efficacious vaccines, pertussis still ranks among the major causes of childhood mortality worldwide. Two types of pertussis vaccines are currently available, whole-cell, and the more recent acellular vaccines ...
Pascal Feunou Feunou +2 more
doaj +1 more source
mBio, 2018 Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki +8 more
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Improving specificity of Bordetella pertussis detection using a four target real-time PCR. [PDF]
PLoS ONE, 2017 The incidence of whooping cough, a contagious respiratory disease caused by Bordetella pertussis, is on the rise despite existing vaccination programmes.
Helena Martini +4 more
doaj +1 more source
Validation and implementation of a diagnostic algorithm for DNA Detection of Bordetella pertussis, B. parapertussis, and B-holmesii in a Pediatric Referral Hospital in Barcelona, Spain [PDF]
, 2019 This study aimed to validate a comprehensive diagnostic protocolbased on real-time PCR for the rapid detection and identification ofBordetella per-tussis,Bordetella parapertussis, andBordetella holmesii, as well as its implementationin the diagnostic ...
Acosta Argueta, Lesly María +5 more
core +2 more sources
Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes [PDF]
Journal of Bacteriology, 1987 Pertussis toxin, the major virulence factor of Bordetella pertussis, is not produced by the closely related species Bordetella parapertussis and Bordetella bronchiseptica. It is shown here that these two species possess but do not express the complete toxin operon.
B, Aricò, R, Rappuoli
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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core +2 more sources
New Microbes and New Infections, 2015 Between January 2013 and December 2014, we conducted laboratory-based surveillance of pertussis using multitarget real-time PCR, which discriminates among Bordetella pertussis, Bordetella parapertussis, Bordetella holmesii and Mycoplasma pneumoniae.
K. Kamachi +5 more
doaj +1 more source
Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]
, 2018 Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén +5 more
core +2 more sources