Investigating genome reduction of Bordetella pertussis using a multiplex PCR-based reverse line blot assay (mPCR/RLB) [PDF]
BACKGROUND: The genetic composition of the bacterium causing whooping cough, Bordetella pertussis, has been investigated using microarray studies in order to examine potential genetic contributors to the disease re-emergence in the past decade.
Connie Lam +4 more
core +1 more source
Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert +18 more
wiley +1 more source
Expression of pertussis toxin in Bordetella bronchiseptica and Bordetella parapertussis carrying recombinant plasmids [PDF]
Pertussis toxin is produced only by strains of Bordetella pertussis. Cloned genes encoding pertussis toxin from B. pertussis were transferred into Bordetella bronchiseptica and Bordetella parapertussis by conjugation. These transconjugants expressed pertussis toxin at levels comparable to those expressed by B. pertussis. The toxin made by these strains
C K, Lee, A, Roberts, S, Perrin
openaire +2 more sources
Saliva and Anterior Nasal Samples for Detecting Respiratory Viruses in Children
ABSTRACT For detecting respiratory viruses, a nasopharyngeal swab sample for polymerase chain reaction (PCR) assays has been the benchmark. Less discomfort related to sampling is requested especially for children, and thus other sample types have been suggested.
Anu Haaramo +5 more
wiley +1 more source
Molecular typing ofBordetella parapertussisisolates circulating in Pakistan [PDF]
Although a whole-cell pertussis vaccine was introduced in Pakistan in 1980, little is known about the pertussis prevalence and circulating strains in Pakistan. The aim of this study was to analyze Bordetella parapertussis isolates circulating between 2005 and 2009 in Pakistan and to compare them with those found in other countries during different ...
Bokhari, Habib +9 more
openaire +3 more sources
ABSTRACT Background Human metapneumovirus (hMPV) has been increasingly recognized as a major contributor to respiratory infections in all age groups. Owing to its recent discovery, available data on the burden of hMPV in adults are still scant and heterogeneous.
Alexander Domnich +6 more
wiley +1 more source
Comparison of Bordetella species identification among differing rt-PCR assays in the United States
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole +7 more
doaj +1 more source
The Role of Bordetella Infections in Patients with Acute Exacerbation of Chronic Bronchitis [PDF]
: Background: : Acute exacerbations of chronic bronchitis (AECB) are associated with a variety of viral and bacterial infectious agents, some of which are potentially preventable by immunization. Bordetella pertussis, which causes whooping cough, has not
Bonhoeffer, J. +4 more
core
Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family [PDF]
Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship.
Afonso de Menezes, Claudia Beatriz +39 more
core +6 more sources
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling +4 more
wiley +1 more source

