Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]
, 2010 Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Dortmans, J.C.F.M. +3 more
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Pathogenesis of Borna disease [PDF]
, 1993 Borna disease represents a unique model of a virus-induced immunological disease of the brain. Naturally occurring in horses and sheep, the mechanisms of pathogenesis have been studied in experimental animals, namely in the rat. Many investigations have revealed that the infection of the natural hosts principally follows the same pathogenic pathways as
L, Stitz, T, Bilzer, J A, Richt, R, Rott
openaire +2 more sources
Borna disease virus and its role in the pathology of animals and humans
Regulatory Mechanisms in Biosystems, 2017 Infectious diseases that are caused by numerous pathogenic microorganisms – bacteria, viruses, protozoa or fungi – can be transmitted from patients or carriers to healthy people or animals.
A. O. Mikheev
doaj +1 more source
Immune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cells [PDF]
, 2012 The adaptive immune response to viral vectors reduces vector-mediated transgene expression from the brain. It is unknown, however, whether this loss is caused by functional downregulation of transgene expression or death of transduced cells.
Ahmed +60 more
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Pathological findings in the red fox (Vulpes vulpes), stone marten (Martes foina) and raccoon dog (Nyctereutes procyonoides), with special emphasis on infectious and zoonotic agents in Northern Germany [PDF]
, 2017 Anthropogenic landscape changes contributed to the reduction of availability of habitats to wild animals. Hence, the presence of wild terrestrial carnivores in urban and peri-urban sites has increased considerably over the years implying an increased ...
Bauer, C. (Christian) +11 more
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Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease
Emerging Infectious Diseases, 2008 Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus.
Kirsi S. Honkavuori +11 more
doaj +1 more source
Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. [PDF]
PLoS ONE, 2008 Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5 ...
Matthias Habjan +11 more
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Borna disease virus (BDV) infection in psychiatric patients and healthy controls in Iran [PDF]
, 2014 Background Borna disease virus (BDV) is an evolutionary old RNA virus, which infects brain and blood cells of humans, their primate ancestors, and other mammals.
Atashi, Hasti +7 more
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Tardive dyskinetic syndrome in rats infected with Borna disease virus
Neurobiology of Disease, 1994 Tardive Dyskinesia (TD) is a hyperkinetic movement disorder caused by chronic treatment of psychiatric patients with dopamine (DA) receptor blocking drugs (Stacy & Jankovic 1991).
Marylou V. Solbrig +3 more
doaj +1 more source
Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
, 2019 Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda +7 more
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