Results 61 to 70 of about 473,462 (215)

„Borna disease virus 1“(BoDV-1)-Enzephalitis eines 18-Jährigen außerhalb des bisher bekannten Endemiegebietes

DGNeurologie, 2022
Fallbeschreibung Ein bisher gesunder 18-jähriger Mann entwickelte subakut Kopfschmerzen, hohes Fieber bis 39 °C, Desorientiertheit, Halluzinationen und eine Ataxie, weswegen eine stationäre Aufnahme notwendig wurde.
T. Meyer, D. Tappe, D. Hasan, M. Rust, J. B. Schulz, J. Schiefer, S. C. Tauber   +6 more
semanticscholar   +1 more source

New World camelids are sentinels for the presence of Borna disease virus.

Transboundary and Emerging Diseases, 2021
Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe.
A. Malbon, R. Dürrwald, J. Kolodziejek, N. Nowotny, Ralph Kobera, D. Pöhle, A. Muluneh, E. Dervas, C. Cebra, F. Steffen, G. Paternoster, C. Gerspach, M. Hilbe   +12 more
semanticscholar   +1 more source

Heat stress is a potent stimulus for enhancing rescue efficiency of recombinant Borna disease virus. [PDF]

, 2014
Recently developed vector systems based on Borna disease virus (BDV) hold promise as platforms for efficient and stable gene delivery to the central nervous system (CNS). However, because it currently takes several weeks to rescue recombinant BDV (rBDV),
Honda, Tomoyuki, Kojima, Shohei, Matsumoto, Yusuke, Tomonaga, Keizo   +3 more
core   +1 more source

Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene) [PDF]

, 2009
Background Borna disease virus (BDV) is the type member of the Bornaviridae, a family of viruses that induce often fatal neurological diseases in horses, sheep and other animals, and have been proposed to have roles in certain psychiatric diseases of ...
Courtney E Garry, Robert F Garry
core   +3 more sources

Authentic Borna disease virus transcripts are spliced less efficiently than cDNA-derived viral RNAs [PDF]

, 2000
Borna disease virus (BDV) is a non-segmented, negative-strand RNA virus that replicates and transcribes its genome in the nucleus of infected cells. It uses the cellular splicing machinery to generate a set of alternatively spliced mRNAs from the 2.8 and
Jehle, Christian, Lipkin, W. Ian, Marion, Rosa M., Schwemmle, Martin, Staeheli, Peter   +4 more
core   +2 more sources

Within host RNA virus persistence : mechanisms and consequences [PDF]

, 2017
RER is funded by the Wellcome Trust, UK (Grant 101788/Z/13/Z) and DEG by US National Institutes of Health (R01 NS038932).In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all ...
Griffin, Diane E., Randall, Richard E.
core   +1 more source

Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease. [PDF]

, 2019
Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes and myeloid cells are thought to be primarily responsible for white ...
Adami, Ager, Aharonowiz, Anghelina, Ben-Hur, Ben-Hur, Bergmann, Bergmann, Blanc, Blanc, Blurton-Jones, Brnic, Brustle, Cantuti-Castelvetri, Carbajal, Chang, Chen, Chen, Chucair-Elliott, Dandekar, Deshmukh, Dunnett, Fleming, Fleming, Frampton, Gage, Giovannoni, Glass, Gonzalez, Greenberg, Gupta, Halfpenny, Hardison, Hatch, Healy, Hosking, Huang, Ireland, Karamita, Keirstead, Kendall, Kerschensteiner, Kucharova, Lane, Lassmann, Lassmann, Lin, Lindborg, Lucchinetti, Mangale, Marie, Mei, Mei, Mei, Minagawa, Muller, Neumann, Oksenberg, Palfi, Parra, Pewe, Phares, Phillips, Picard-Riera, Plaisted, Plaisted, Pluchino, Pluchino, Poser, Prineas, Prineas, Ramakrishna, Redwine, Reidling, Rowe, Roy, Ruckh, Ruller, Salazar, Sarma, Schaumburg, Schlesinger, Smith, Steinman, Stohlman, Tabor-Godwin, Totoiu, Trandem, Traugott, Wang, Weinger, Weinger, Weinshenker, Wheeler, Whitman, Wu, Yagita, Zhang, Zhou, Zhu   +99 more
core   +1 more source

The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability. [PDF]

, 2016
It was recently discovered that vertebrate genomes contain multiple endogenised nucleotide sequences derived from the non-retroviral RNA bornavirus.
A Aswad, A Dammermann, A Dupressoir, A Katzourakis, AJ Faragher, BR Mardin, CJ Snow, CJ Staples, CJ Staples, CJ Staples, CZ Zhang, DN Simon, H Nakano, HJ Nam, HJ Nam, K Fujino, K Sofuku, M Horie, M Horie, M Horie, NF Parrish, O Planz, P He, P Jern, PC Conroy, R Malfavon-Borja, RD Beveridge, RD Paulsen, S Mi, T Kobayashi, T Nagai, VA Belyi, VM Zhdanov, Y Zhang   +33 more
core   +2 more sources

Borna disease virus 1 induces ferroptosis, contributing to lethal encephalitis

Journal of Medical Virology
Borna disease virus 1 (BoDV‐1) is a neurotropic RNA virus that has been linked to fatal BoDV‐1 encephalitis (BVE) in humans. Ferroptosis represents a newly recognized kind of programmed cell death that marked by iron overload and lipid peroxidation ...
Qing Tan, Hongli Yang, Yong He, Xia Shen, Lin Sun, Xiaoyan Du, Gangqiang Lin, Na Zhou, Nishi Wang, Qian Zhou, Dan Liu, Xiaoyan Xu, Libo Zhao, Peng Xie   +13 more
semanticscholar   +1 more source

Borna Disease Virus and the Brain

Brain Research Bulletin, 1997
Viruses with the ability to establish persistent infection in the central nervous system (CNS) can induce progressive neurologic disorders associated with diverse pathological manifestations. Clinical, epidemiological, and virological evidence supports the hypothesis that viruses contribute to human mental diseases whose etiology remains elusive ...
Gonzalez–Dunia, Daniel, Sauder, Christian, De La Torre, Juan Carlos   +2 more
openaire   +3 more sources