Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany [PDF]
Emerging Microbes and Infections, 2022 In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Christina Frank +14 more
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Molecular epidemiology of human Borna disease virus 1 infection revisited [PDF]
Emerging Microbes and Infections, 2022 Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
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Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1 [PDF]
Viruses, 2022 Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
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Healthcare-associated exposure to Borna disease virus 1 (BoDV-1) [PDF]
Journal of Occupational Medicine and Toxicology, 2022 The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Judith Reinmiedl +5 more
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Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study [PDF]
Emerging Microbes and Infections, 2023 In 2018, Borna Disease Virus 1 (BoDV-1) was confirmed as a human zoonotic pathogen causing rare but fatal encephalitis in Germany. While diagnostic procedures and the clinical picture have been described, epidemiology remains mysterious.
Kirsten Pörtner +5 more
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Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report [PDF]
BMC Infectious Diseases, 2021 Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe +13 more
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Is vaccination a feasible public health strategy against fatal Borna disease virus 1 (BoDV-1) encephalitis? An epidemiological perspective. [PDF]
PLoS PathogensHuman Borna disease virus 1 (BoDV-1) encephalitis is characterized by rapid clinical progression, an absence of a causal therapy and an extremely high case fatality rate.
Kirsten Pörtner +7 more
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IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study [PDF]
Viruses, 2023 More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Lisa Eidenschink +18 more
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Magnetic resonance imaging of human variegated squirrel bornavirus 1 (VSBV-1) encephalitis reveals diagnostic pattern indistinguishable from Borna disease virus 1 (BoDV-1) encephalitis but typical for bornaviruses [PDF]
Emerging Microbes and Infections, 2023 Human bornavirus encephalitis is an emerging disease caused by the variegated squirrel bornavirus 1 (VSBV-1) and the Borna disease virus 1 (BoDV-1).
Monika Huhndorf +7 more
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Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease [PDF]
Emerging Microbes and Infections, 2022 Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch +11 more
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