Results 31 to 40 of about 5,371 (185)

Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines

Viruses, 2022
(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald, Jolanta Kolodziejek, Djin-Ye Oh, Sibylle Herzog, Heinrich Liebermann, Nikolaus Osterrieder, Norbert Nowotny   +6 more
doaj   +1 more source

Evolutionarily Conserved Interaction between the Phosphoproteins and X Proteins of Bornaviruses from Different Vertebrate Species. [PDF]

, 2012
Bornavirus, a non-segmented, negative-strand RNA viruses, is currently classified into several genetically distinct genotypes, such as Borna disease virus (BDV) and avian bornaviruses (ABVs).
Francischetti, Ivo M B, Fujino, Kan, Honda, Tomoyuki, Horie, Masayuki, Matsumoto, Yusuke, Nakamura, Shoko, Tomonaga, Keizo   +6 more
core   +10 more sources

Distinct 5' UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses. [PDF]

Microbiol Immunol
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Wu MC, Kanda T, Komorizono R, Sakai M, Leacy A, Susta L, Makino A, Tomonaga K.   +7 more
europepmc   +2 more sources

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

Emerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann, Dennis Rubbenstroth, Daniel Cadar, Corinna Thomé-Bolduan, Petra Eggert, Alexander Schlaphof, Frank Leypoldt, Martin Stangel, Thorsten Fortwängler, Florian Hoffmann, Andreas Osterman, Sabine Zange, Hans-Helmut Niller, Klemens Angstwurm, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Martin Beer, Jonas Schmidt-Chanasit, Dennis Tappe   +19 more
doaj   +1 more source

1-β- d -Arabinofuranosylcytosine Inhibits Borna Disease Virus Replication and Spread [PDF]

Journal of Virology, 2002
ABSTRACT Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that causes neurological diseases in a variety of warm-blooded animal species. There is general consensus that BDV can also infect humans, being a possible zoonosis.
Jeffrey J, Bajramovic, Sylvie, Syan, Michel, Brahic, Juan Carlos, de la Torre, Daniel, Gonzalez-Dunia   +4 more
openaire   +2 more sources

Experimental infection of shrews (<i>Crocidura russula</i>) with Borna disease virus 1: Insights into viral spread and shedding. [PDF]

PNAS Nexus
Abstract Numbers of human encephalitis cases caused by infection with Borna disease virus 1 (BoDV1) increase continuously in endemic areas. The reservoir host of BoDV1 is the bicolored white-toothed shrew, albeit few naturally infected individuals of other shrew species have been detected.
Nobach D, Raeder L, Müller J, Herzog S, Eickmann M, Herden C.   +5 more
europepmc   +3 more sources

Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis. [PDF]

Infection
Abstract Background Within endemic regions in southern and eastern Germany, Borna disease virus 1 (BoDV-1) causes rare zoonotic spill-over infections in humans, leading to encephalitis with a high case-fatality risk.
Bauswein M, Eid E, Eidenschink L, Schmidt B, Gessner A, Tappe D, Cadar D, Böhmer MM, Jockel L, van Wickeren N, Garibashvili T, Wiesinger I, Wendl C, Heckmann JG, Angstwurm K, Freyer M.   +15 more
europepmc   +5 more sources

Understanding the Enigmatic Dance of Immune-Mediated Viral Infections and Their Pathogenetic Mechanisms. [PDF]

Vet Med Sci
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Karabulut MC, Oğuzoğlu TÇ.
europepmc   +2 more sources

Borna Disease Virus Phosphoprotein Binds a Neurite Outgrowth Factor, Amphoterin/HMG-1 [PDF]

Journal of Virology, 2001
ABSTRACT The Borna disease virus (BDV) p24 phosphoprotein is an abundant protein in BDV-infected cultured cells and animal brains. Therefore, there is a possibility that binding of the p24 protein to cellular factor(s) induces functional alterations of infected neural cells in the brain.
W, Kamitani, Y, Shoya, T, Kobayashi, M, Watanabe, B J, Lee, G, Zhang, K, Tomonaga, K, Ikuta   +7 more
openaire   +2 more sources

Screening red foxes (Vulpes vulpes) for possible viral causes of encephalitis [PDF]

, 2016
Background: Next to various known infectious and non-infectious causes, the aetiology of non-suppurative encephalitis in red foxes (Vulpes vulpes) often remains unclear.
Becker, Sabrina, Bourg, Manon, Eickmann, Markus, Hamann, Hans-Peter, Herden, Christiane, Herzog, Sibylle, Hoffmann, Bernd, Höper, Dirk, Lange-Herbst, Hildburg, Nesseler, Anne, Nobach, Daniel   +10 more
core   +2 more sources