Results 11 to 20 of about 605 (152)

The structure of the mammalian bornavirus polymerase complex [PDF]

Nature Communications
Borna disease virus 1 (BoDV-1) is a non-segmented RNA virus with one of the smallest known RNA virus genomes. BoDV-1 replicates in the nucleus of infected cells using a virally encoded polymerase complex composed of the large protein and phosphoprotein ...
Loïc Carrique, Franziska Günl, Adrian Deng, Jonathan M. Grimes, Jeremy R. Keown   +4 more
doaj   +4 more sources

Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]

npj Viruses
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda, Pauline Dianne Santos, Dirk Höper, Martin Beer, Dennis Rubbenstroth, Keizo Tomonaga   +5 more
doaj   +4 more sources

Comparative study of virus and lymphocyte distribution with clinical data suggests early high dose immunosuppression as potential key factor for the therapy of patients with BoDV-1 infection [PDF]

Emerging Microbes and Infections
Borna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and ...
Yannik Vollmuth, Nicola Jungbäck, Tatiana Mögele, Friederike Schmidt-Graf, Silke Wunderlich, Mareike Schimmel, Camilla Rothe, Leonhard Stark, Jürgen Schlegel, Georg Rieder, Thomas Richter, Tina Schaller, Dennis Tappe, Bruno Märkl, Kaspar Matiasek, Friederike Liesche-Starnecker   +15 more
doaj   +5 more sources

Genetic stability of the open reading frame 2 (ORF2) of borna disease virus 1 (BoDV-1) distributed in cattle in Hokkaido. [PDF]

J Vet Med Sci, 2021
Borna disease virus (BoDV) is a neurotropic virus that causes several infections in humans and neurological diseases in a wide range of animals worldwide. BoDV-1 has been molecularly and serologically detected in many domestic and wild animals in Japan; however, the genetic diversity of this virus and the origin of its infection are not fully ...
Sukmak M, Okamoto M, Ando T, Hagiwara K.
europepmc   +4 more sources

New World camelids are sentinels for the presence of Borna disease virus [PDF]

Transboundary and Emerging Diseases, Volume 69, Issue 2, Page 451-464, March 2022., 2021
Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe.
Cebra, Christopher, Dervas, Eva, Durrwald, Ralf, Gerspach, Christian, Hilbe, Monika, Kobera, Ralph, Kolodziejek, J., Malbon, Alexandra, Muluneh, Aemero, Nowotny, N., Paternoster, Giulia, Pohle, Dietrich, Steffen, Frank   +12 more
core   +4 more sources

No evidence of an association of multiple sclerosis (MS) with Borna disease virus 1 (BoDV-1) infections in patients within an endemic region: a retrospective pilot study. [PDF]

Infection, 2023
Abstract Background Borna disease virus 1 (BoDV-1) causes rare human infections within endemic regions in southern and eastern Germany. The infections reported to date have been linked to severe courses of encephalitis with high mortality and mostly irreversible symptoms.
Bauswein M, Knoll G, Schmidt B, Gessner A, Hemmer B, Flaskamp M.   +5 more
europepmc   +7 more sources

Lethal Borna disease virus 1 (BoDV-1) infections of humans and animals – in-depth molecular epidemiology and phylogeography: [Preprint] [PDF]

, 2023
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a progressive and mostly fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed ...
Baumgärtner, Wolfgang, Bauswein, Markus, Beer, Martin, Cadar, Daniel, Dürrwald, Ralf, Ebinger, Arnt, Ensser, Armin, Frank, Christina, Fürstenau, Jenny, Hansmann, Florian, Haring, Viola, Herms, Jochen, Hoffmann, Bernd, Homeier-Bachmann, Timo, Kolodziejek, Jolanta, Korn, Klaus, Liesche-Starnecker, Friederike, Matiasek, Kaspar, Mundhenk, Lars, Müller, Matthias, Neubauer-Juric, Antonie, Niller, Hans-Helmut, Nobach, Daniel, Nowotny, Norbert, Pfaff, Florian, Pörtner, Kirsten, Rubbenstroth, Dennis, Ruf, Viktoria, Santos, Pauline, Schlegel, Jürgen, Schlottau, Kore, Schmidt, Barbara, Seuberlich, Torsten, Suchowski, Marcel, Tappe, Dennis, Ulrich, Rainer G., Ulrich, Reiner   +36 more
core   +2 more sources

Evidence of rustrela virus-associated feline staggering disease in Sweden since the 1970s [PDF]

Acta Veterinaria Scandinavica
Background Staggering disease (SD) is a severe neurological disease that has been regularly reported in Swedish cats since the beginning of the 1970s.
Emma Thilén, Dennis Rubbenstroth, Sofia Tengstrand, Florian Pfaff, Jonas Johansson Wensman, Cecilia Ley   +5 more
doaj   +4 more sources

Ribavirin Treatment for Severe Schizophrenia with Anti-Borna Disease Virus 1 Antibodies 30 Years after Onset

Case Reports in Psychiatry, 2023
Objective. Borna disease virus 1 (BoDV-1) was proven to cause fatal encephalitis in humans in 2018. However, the effects of persistent infections remain unclear.
Hidenori Matsunaga, Akio Fukumori, Kohji Mori, Takashi Morihara, Shunsuke Sato, Kyoko Kitauchi, Kanta Yanagida, Kazumi Taguchi, Tomoyuki Honda, Keizo Tomonaga   +9 more
doaj   +2 more sources

Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis. [PDF]

Infection
Abstract Background Within endemic regions in southern and eastern Germany, Borna disease virus 1 (BoDV-1) causes rare zoonotic spill-over infections in humans, leading to encephalitis with a high case-fatality risk.
Bauswein M, Eid E, Eidenschink L, Schmidt B, Gessner A, Tappe D, Cadar D, Böhmer MM, Jockel L, van Wickeren N, Garibashvili T, Wiesinger I, Wendl C, Heckmann JG, Angstwurm K, Freyer M.   +15 more
europepmc   +5 more sources