Results 151 to 160 of about 3,395,639 (199)

Bone Marrow-Derived Macrophages Loaded with Boron Carbide Nanoparticles Targeting the Glioblastoma Microenvironment for Boron Neutron Capture Therapy. [PDF]

Int J Nanomedicine
Rudawska A, Szczygieł A, Węgierek-Ciura K, Mierzejewska J, Kozień D, Żeliszewska P, Chaszczewska-Markowska M, Rusiniak P, Wątor K, Pędzich Z, Pajtasz-Piasecka E, Szermer-Olearnik B.   +11 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

New horizons for therapy based on the boron neutron capture reaction

Trends in Molecular Medicine, 1998
Boron neutron capture therapy (BNCT) is currently undergoing clinical trials in the USA, Japan and The Netherlands with patients afflicted with deadly brain cancer (glioblastoma multiforme) or melanoma. This therapy relies on a binary process in which the capture of a slow neutron by a 10B nucleus leads to an energetic nuclear fission reaction, with ...
M F Hawthorne
exaly   +3 more sources

Engineering Design of a Spallation Reaction-Based Neutron Generator for Boron Neutron Capture Therapy

Journal of Nuclear Science and Technology, 2006
An engineering design of an epithermal neutron generator for boron neutron capture therapy (BNCT) has been completed, which utilizes the spallation reaction by protons accelerated to 50 MeV. The critical issues for realization of the neutron generator are the mechanical structure of a target with cooling capability and its integrity under operating ...
Mamoru Baba, Shunsuke Yonai
exaly   +4 more sources

Evaluations for prompt-gamma imaging of boron and hydrogen neutron capture reactions in boron neutron capture therapy (BNCT)

, 2002
Boron neutron capture therapy (BNCT) is used for malignant brain tumours, with a tumour selective 10B-compound as a targeting agent of the radiation dose [1]. In this project, the possibility to measure on-line distribution of the boron neutron capture vents in patient's head during a BNCT irradiation is studied.
Auterinen, Iiro, Kotiluoto, Petri, Anttila, Kai, Serén, Tom, Renvall, Tommi, Kekki, Tommi, Tiitta, Antero   +6 more
core   +8 more sources

Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2005
The boron neutron capture (BNC) reaction results from the interaction of 10B with low-energy thermal neutrons and gives rise to highly damaging lithium and alpha-particles. In this work the genotoxicity caused by the BNC reaction in V79 Chinese hamster cells was evaluated in the presence of poly(ADP-ribosyl)ation inhibitors. Poly(ADP-ribose) polymerase-
Nuno G. Oliveira, Jose Rueff, Matilde F. Castro   +2 more
exaly   +4 more sources

First optical observation of 10B-neutron capture reactions using a boron-added liquid scintillator for quality assurance in boron neutron capture therapy

Radiological Physics and Technology, 2021
10B-neutron capture was observed optically using a boron-added liquid scintillator. Trimethyl borate was dissolved in a commercially available liquid scintillator at natural boron concentrations of approximately 1 wt% and 0.25 wt%. The boron-added liquid scintillator was placed in a phantom quartz bottle and irradiated by thermal neutrons (~ 105 n/[cm2
Akihiro, Nohtomi, Hideya, Maeda, Naoya, Sakamoto, Genichiro, Wakabayashi, Takushi, Takata, Yoshinori, Sakurai   +5 more
openaire   +2 more sources

Colocalization of tracks from boron neutron capture reactions and images of isolated cells

Applied Radiation and Isotopes, 2021
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells.
Ian Postuma, Patrizia Sommi, Agostina Vitali, Diyun Shu, Greta di Martino, Laura Cansolino, Cinzia Ferrari, Vittorio Ricci, Chiara Magni, Nicoletta Protti, Setareh Fatemi, Umberto Anselmi Tamburini, Silva Bortolussi, Saverio Altieri   +13 more
openaire   +3 more sources

Dosimetry of the boron neutron capture reaction for BNCT and BNCEFNT

Strahlentherapie und Onkologie, 1999
The use of paired proportional counters, constructed from A-150 tissue equivalent plastic (TEP) and A-150 TEP loaded with an appropriate amount of 10B (50 to 200 ppm), for the dosimetry of the boron neutron capture reaction has been investigated for several years at the Gershenson Radiation Oncology Center. This method has been used for determining the
J, Burmeister, C, Kota, R L, Maughan
openaire   +2 more sources

Demonstration of the bactericidal effects of the boron neutron capture reaction

Applied Radiation and Isotopes, 2018
This pilot study represents a paradigm shift, using BNCT for the treatment of bacterial overgrowth on surgically implanted medical devices. In this study, titanium diboride disks were inoculated with S. aureus and irradiated in a thermal neutron beam. After a delivery of 2.6 × 1012 n/cm2 the surviving fraction of S. aureus on an irradiated disk was 3.1 
Charles A, Maitz, John D, Brockman, Ming, Yang, Shuping, Zhang, James, Stannard, David, Volgas, John M, Gahl   +6 more
openaire   +2 more sources

Comparison of Radiation Effects of Gadolinium and Boron Neutron Capture Reactions

Strahlentherapie und Onkologie, 2000
Cell survival assays were performed to evaluate the effects of radiations released during neutron capture reactions by gadolinium-157, boron-10 and by the combination of both.Single cell suspensions with or without Gd-157 and/or B-10 were exposed to thermal neutrons produced by the Kyoto University reactor, and standard cell survival curves were ...
K, Tokuuye, N, Tokita, Y, Akine, H, Nakayama, Y, Sakurai, T, Kobayashi, K, Kanda   +6 more
openaire   +2 more sources