Results 11 to 20 of about 3,395,639 (199)

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine

Biology, 2021
Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment exploiting a nuclear reaction occurring in tumor cells [...]
Silva Bortolussi, Yuan-Hao Liu, Ignacio Porras   +2 more
doaj   +2 more sources

Experimental study on Compton camera for boron neutron capture therapy applications

Scientific Reports, 2023
Boron neutron capture therapy (BNCT) is a high-dose-intensive radiation therapy that has gained popularity due to advancements in accelerator neutron sources.
M. Sakai, S. Tamaki, I. Murata, R. K. Parajuli, A. Matsumura, N. Kubo, M. Tashiro   +6 more
doaj   +2 more sources

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Journal of Pharmacological Sciences, 2019
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by ...
Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai   +12 more
doaj   +2 more sources

Boron Neutron Capture Therapy: Microdosimetry at Different Boron Concentrations

Applied Sciences, 2023
This paper explores the role of microdosimetry in boron neutron capture therapy (BNCT), a cancer treatment involving the selective accumulation of boron-containing compounds in cancer cells, followed by neutron irradiation.
Valeria Conte, Anna Bianchi, Anna Selva
doaj   +2 more sources

Theranostics in boron neutron capture therapy [PDF]

, 2021
Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied ...
Panza, Luigi, Kellert, Martin, Hey-Hawkins, Evamarie, Sauerwein, Wolfgang A. G., Imperio, Daniela, Balcerzyk, Marcin, Sancey, Lucie   +6 more
core   +1 more source

In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

Scientific Reports, 2022
While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly relies on gamma rays and Auger electrons ...
Woonghee Lee, Kyung Won Kim, Jeong Eun Lim, Swarbhanu Sarkar, Jung Young Kim, Yongmin Chang, Jeongsoo Yoo   +6 more
doaj   +1 more source

Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy

Nature Communications, 2023
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li ...
Yaxin Shi, Zhibin Guo, Qiang Fu, Xinyuan Shen, Zhongming Zhang, Wenjia Sun, Jinqiang Wang, Junliang Sun, Zizhu Zhang, Tong Liu, Zhen Gu, Zhibo Liu   +11 more
doaj   +1 more source

Optimising neutron production from compact low energy accelerators [PDF]

, 2012
There is currently much development in accelerator based methods to provide flexible and reliable neutron generators, in response to a decline in the availability of nuclear reactors.
Cywinski, Robert, Bungau, Adriana, Edgecock, R., Ratcliffe, N, Barlow, Roger, Bungau, A., Ratcliffe, N., Edgecock, T. R., Barlow, R.   +8 more
core   +3 more sources

ASSESSMENT OF THE EFFECT OF BORON NEUTRON CAPTURE THERAPY ON TUMOR CELL LINES AND PRIMARY EMBRYONIC CELL CULTURE

Сибирский онкологический журнал, 2021
Introduction. Boron neutron capture therapy (bnct) is a promising method for treating tumors, in particular, infiltrative malignant tumors, due to the selective destruction of tumor cells without damaging the surrounding normal tissues.
V. V. Kanygin, A. I. Kasatova, I. A. Razumov, E. L. Zavyalov, A. I. Kichigin, R. A. Mukhamadiyarov, S. Yu. Taskaev   +6 more
doaj   +1 more source

The basis and advances in clinical application of boron neutron capture therapy

Radiation Oncology, 2021
Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He, Jiyuan Li, Ping Jiang, Suqing Tian, Hao Wang, Ruitai Fan, Junqi Liu, Yuyan Yang, Zhibo Liu, Junjie Wang   +9 more
doaj   +1 more source