Results 21 to 30 of about 3,395,639 (199)

Design of a scintillator-based prompt gamma camera for boron-neutron capture therapy: Comparison of SrI2 and GAGG using Monte-Carlo simulation

Nuclear Engineering and Technology, 2021
Boron–neutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutron reactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation is essential for ensuring the accuracy and safety of BNCT. We
Minho Kim, Bong Hwan Hong, Ilsung Cho, Chawon Park, Sun-Hong Min, Won Taek Hwang, Wonho Lee, Kyeong Min Kim   +7 more
doaj   +1 more source

A Review of Boron Neutron Capture Therapy: Its History and Current Challenges [PDF]

International Journal of Particle Therapy, 2022
Mechanism of Action: External beam, whether with photons or particles, remains as the most common type of radiation therapy. The main drawback is that radiation deposits dose in healthy tissue before reaching its target.
Will H. Jin, MD, Crystal Seldon, MD, Michael Butkus, PhD, Wolfgang Sauerwein, MD, Huan B. Giap, MD, PhD   +4 more
doaj   +1 more source

Low energy fusion for a safe and compact neutron source [PDF]

, 2013
Neutrons are primarily produced at large international facilities using either spallation reactions or nuclear fission. There is a demand for small scale neutron production for use at hospitals and borders for a variety of applications.
Seviour, Rebecca, Albright, S.
core   +3 more sources

Measurement of the applicability of various experimental materials in a medically relevant reactor neutron source part two: Study of H3BO3 and B-DTPA under neutron irradiation

Nuclear Engineering and Technology, 2023
Experiments related to Boron Neutron Capture Therapy (BNCT) accomplished at the Institute of Nuclear Techniques (INT), Budapest University of Technology and Economics (TUB) are presented.
Ezddin Hutli, Peter Zagyvai
doaj   +1 more source

Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation

Cells, 2021
Background: Boron neutron capture therapy (BNCT) is a nuclear reaction-based tumor cell-selective particle irradiation method. High-dose methotrexate and whole-brain radiation therapy (WBRT) are the recommended treatments for primary central nervous ...
Kohei Yoshimura, Shinji Kawabata, Hideki Kashiwagi, Yusuke Fukuo, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Tsubasa Watanabe, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Masahiko Wanibuchi   +13 more
doaj   +1 more source

Apoptosis through Bcl-2/Bax and cleaved caspase up-regulation in melanoma treated by boron neutron capture therapy. [PDF]

PLoS ONE, 2013
Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam.
Fernanda Faião-Flores, Paulo Rogério Pinto Coelho, João Dias Toledo Arruda-Neto, Silvya Stuchi Maria-Engler, Manoela Tiago, Vera Luiza Capelozzi, Ricardo Rodrigues Giorgi, Durvanei Augusto Maria   +7 more
doaj   +1 more source

Boron Neutron Capture Therapy - A Literature Review [PDF]

Journal of Clinical and Diagnostic Research, 2016
Boron Neutron Capture Therapy (BNCT) is a radiation science which is emerging as a hopeful tool in treating cancer, by selectively concentrating boron compounds in tumour cells and then subjecting the tumour cells to epithermal neutron beam radiation ...
Kavitaa Nedunchezhian, Nalini Aswath, Manigandan Thiruppathy, Sarumathi Thirugnanamurthy   +3 more
doaj   +1 more source

Biological Distribution in Patients of Boron Agent 4-Borono-L-Phenylalanine for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
Boron neutron capture therapy(BNCT) is a binary targeted radiation therapy in which neutron does not directly provide tumor dose. The dose produced by the 10B(n, α)7Li capture reaction will be deposited in tumor cells by using targeted 10B agents ...
ZHU Xia-yang, LIU Kai, SHAO Yu-jun, JIN Cong-jun, ZHAO Chun-yuan, CHONG Yi-zheng, GUO Zhi-bin, SUN Qi, LIU Zhi-bo, LIU Tong, ZHANG Zi-zhu   +10 more
doaj   +1 more source

Feasibility of Prompt Gamma-Ray Imaging in BNCT: SPECT-Based MCNP Simulations of Boron and Hydrogen Capture Events [PDF]

Journal of Radiation Protection and Research
Background Boron neutron capture therapy (BNCT) is a targeted radiotherapy that selectively destroys cancer cells by delivering compounds enriched in boron-10 (10B) that preferentially accumulate in tumors.
Milad Mohammedali, Wonho Lee
doaj   +1 more source

Principles and Clinical Applications of Boron Neutron Capture Therapy

Xiehe Yixue Zazhi, 2023
Boron neutron capture therapy (BNCT) is an advanced radiation therapy technique that is rapidly developing in the field of cancer treatment. This technique, an atomic-level binary targeted therapy, kills cancer cells by causing a 10B(n, α)7Li nuclear ...
LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li   +13 more
doaj   +1 more source