Results 41 to 50 of about 6,117,045 (351)

A boronic acid–rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing

open access: yesScience Advances, 2019
We report the rational design of a polymer with unprecedented and robust efficiency for cytosolic delivery of native proteins. Cytosolic protein delivery is of central importance for the development of protein-based biotechnologies and therapeutics ...
Chongyi Liu   +5 more
semanticscholar   +1 more source

Copper(I)-Phosphinite Complexes in Click Cycloadditions: Three-Component Reactions and Preparation of 5-Iodotriazoles [PDF]

open access: yes, 2016
© 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one-pot azidonation/cycloaddition of
Crosbie, P   +3 more
core   +3 more sources

The combined-disk boronic acid test as an accurate strategy for the detection of KPC carbapenemase in Central America

open access: yesJournal of Infection in Developing Countries, 2016
Introduction: Carbapenemase-producing Klebsiella pneumoniae (KPC) outbreaks may cause a huge economical burden on developing countries. Furthermore, KPC can be challenging to detect.
Julio Zúñiga   +4 more
doaj   +1 more source

Genetically encoded fluorescent redox probes. [PDF]

open access: yes, 2013
Redox processes are involved in almost every cell of the body as a consequence of aerobic life. In the past decades, redox biology has been increasingly recognized as one of the key themes in cell signaling.
Ai, Hui-Wang, Ren, Wei
core   +3 more sources

Phenylboronic acid-diol crosslinked 6-O-vinylazeloyl-d-galactose nanocarriers for insulin delivery [PDF]

open access: yes, 2017
A new block polymer named poly 3-acrylamidophenylboronic acid-b-6-O–vinylazeloyl-d-galactose (p(AAPBA-b-OVZG)) was prepared using 3-acrylamidophenylboronic acid (AAPBA) and 6-O-vinylazeloyl-D-galactose (OVZG) via a two-step procedure involving S-1 ...
Bremner, David H.   +5 more
core   +2 more sources

Strongly Enhanced Antibacterial Action of Copper Oxide Nanoparticles with Boronic Acid Surface Functionality.

open access: yesACS Applied Materials and Interfaces, 2019
Copper oxide nanoparticles (CuONPs) have been widely recognized as good antimicrobial agents but are heavily regulated due to environmental concerns of their postuse. In this work, we have developed and tested a novel type of formulation for copper oxide
Ahmed F. Halbus   +2 more
semanticscholar   +1 more source

Spectroscopic studies of the Chan–Lam amination: a mechanism-inspired solution to boronic ester reactivity [PDF]

open access: yes, 2017
We report an investigation of the Chan–Lam amination reaction. A combination of spectroscopy, computational modeling, and crystallography has identified the structures of key intermediates and allowed a complete mechanistic description to be presented ...
Isidro-Llobet, Albert   +4 more
core   +5 more sources

Mild, Organo-Catalysed Borono-Deamination as a Key to Late-Stage Pharmaceutical Precursors and 18F-Labelled Radiotracers

open access: yesFrontiers in Chemistry, 2022
A tris(pentafluorophenyl)borane catalysed method for the synthesis of boronic acid esters from aromatic amines in yields of up to 93% was devised.
Raúl M. Pérez-García   +4 more
doaj   +1 more source

Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity [PDF]

open access: yes, 2012
A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling.
Balzarini, Jan   +4 more
core   +1 more source

Highly porous photoluminescent diazaborole-linked polymers: synthesis, characterization, and application to selective gas adsorption [PDF]

open access: yes, 2017
The formation of boron–nitrogen (B–N) bonds has been widely explored for the synthesis of small molecules, oligomers, or linear polymers; however, its use in constructing porous organic frameworks remains very scarce.
Arvapally, Ravi K.   +4 more
core   +2 more sources

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