Results 11 to 20 of about 11,886 (207)

Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology

International Journal of Molecular Sciences, 2023
Snakebite envenoming represents a major health problem in tropical and subtropical countries. Considering the elevated number of accidents and high morbidity and mortality rates, the World Health Organization reclassified this disease to category A of ...
J. Cavalcante, Denis Emanuel Garcia de Almeida, N. Santos-Filho, M. A. Sartim, Amanda de Almeida Baldo, Lisele Brasileiro, P. Albuquerque, S. Oliveira, Jacqueline A G Sachett, W. Monteiro, R. S. Ferreira   +10 more
semanticscholar   +1 more source

Massive acute ischemic stroke after Bothrops spp. envenomation in southwestern Colombia: Case report and literature review

Biomédica: revista del Instituto Nacional de Salud, 2022
Bothrops spp. envenomation and its relationship with ischemic stroke has complex pathogenesis. Local effects such as edema, pain, redness, necrosis, and systemic manifestations like coagulation disorders, thrombosis, renal failure, and hemorrhage have ...
Viviana Alexandra Martínez-Villota, Paulo Francisco Mera-Martínez, José Darío Portillo-Miño   +2 more
doaj   +1 more source

Who are the most affected by Bothrops snakebite envenoming in Brazil? A Clinical-epidemiological profile study among the regions of the country

PLoS Neglected Tropical Diseases, 2023
Snakebite envenoming represents an important Neglected Tropical Disease (NTD) that mainly affects tropical and subtropical developing countries according to the World Health Organization (WHO).
W. G. D. da Silva, Lucas de Siqueira Santos, Derick Lira, Karla Patricia De Oliveira Luna, S. Fook, Rômulo Romeu da Nóbrega Alves   +5 more
semanticscholar   +1 more source

Photobiomodulation Therapy to Treat Snakebites Caused by Bothrops atrox

JAMA Internal Medicine, 2023
This randomized clinical trial investigates the feasibility, safety, and efficacy of low-level laser therapy in reducing the local manifestations of Bothrops atrox envenomations.
É. S. Carvalho, A. Souza, D. Melo, Altair Seabra de Farias, Bruna B O Macedo, M. A. Sartim, M. Caggy, B. Rodrigues, G. Ribeiro, Heloísa Nunes Reis, F. Araújo, I. M. da Silva, André Sachett, V. Sampaio, A. Balieiro, S. Zamuner, J. Vissoci, L. Cabral, W. Monteiro, Jacqueline A G Sachett   +19 more
semanticscholar   +1 more source

Clinical and Evolutionary Implications of Dynamic Coagulotoxicity Divergences in Bothrops (Lancehead Pit Viper) Venoms

Toxins, 2022
Despite coagulotoxicity being a primary weapon for prey capture by Bothrops species (lancehead pit vipers) and coagulopathy being a major lethal clinical effect, a genus-wide comparison has not been undertaken.
L. Bourke, C. Zdenek, A. Tanaka-Azevedo, G. P. M. Silveira, S. Sant'Anna, K. Grego, C. F. B. Rodrigues, B. Fry   +7 more
semanticscholar   +1 more source

Aspectos biomédicos y epidemiológicos del accidente ofídico en el departamento del Cauca, Colombia, 2009-2018

Biomédica: revista del Instituto Nacional de Salud, 2021
Introducción. El ofidismo en Colombia es un problema de salud pública, lo cual se hace evidente al examinar los datos epidemiológicos a nivel latinoamericano, pues el país ocupa el tercer lugar en número de accidentes ofídicos después de Brasil y México.
María José Sevilla-Sánchez, Santiago Ayerbe-González, Eliana Bolaños-Bolaños   +2 more
doaj   +1 more source

Snakebites caused by the genera Bothrops and Lachesis in the Brazilian Amazon: a study of factors associated with severe cases and death

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Background: Snakebites are a major problem in developing countries owing to their high morbidity rates, severity, and sequelae. In Brazil, most cases of envenomation are caused by Bothrops and Lachesis snakes.
S. Magalhães, H. M. Peixoto, L. R. S. Freitas, W. Monteiro, M. R. Oliveira   +4 more
semanticscholar   +1 more source

CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite

Mediators of Inflammation, 2022
In the Brazilian Amazon, the snake Bothrops atrox is the primary cause of snakebites. B. atrox (BaV) venom can cause systemic pathophysiological changes such as acute kidney injury (AKI), which leads to the production of chemokines and cytokines in ...
Juliana Costa Ferreira Neves, H. N. Ibiapina, F. Magalhães-Gama, Jacqueline A G Sachett, Iran Mendonça da Silva, K. F. Coelho, E. C. Alves, A. Tarragô, Luiz Carlos de Lima Ferreira, Adriana Malheiro, W. Monteiro, A. G. Costa   +11 more
semanticscholar   +1 more source

Commercial Antivenoms Exert Broad Paraspecific Immunological Binding and In Vitro Inhibition of Medically Important Bothrops Pit Viper Venoms

Toxins, 2022
Snakebite envenoming is a life threatening neglected tropical disease that represents a considerable public health concern in the tropics. Viperid snakes of the genus Bothrops are among those of greatest medical importance in Latin America, and they ...
Jaffer Alsolaiss, Nessrin Alomran, Lauraine K. Hawkins, N. Casewell   +3 more
semanticscholar   +1 more source

Bleeding and Thrombosis: Insights into Pathophysiology of Bothrops Venom-Related Hemostasis Disorders

International Journal of Molecular Sciences, 2021
Toxins from Bothrops venoms targeting hemostasis are responsible for a broad range of clinical and biological syndromes including local and systemic bleeding, incoagulability, thrombotic microangiopathy and macrothrombosis.
S. Larréché, Jean-Philippe Chippaux, L. Chevillard, Simon Mathé, D. Résière, V. Siguret, B. Mégarbane   +6 more
semanticscholar   +1 more source