CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite [PDF]
Mediators of Inflammation, 2022 In the Brazilian Amazon, the snake Bothrops atrox is the primary cause of snakebites. B. atrox (BaV) venom can cause systemic pathophysiological changes such as acute kidney injury (AKI), which leads to the production of chemokines and cytokines in ...
Juliana Costa Ferreira Neves +11 more
doaj +3 more sources
A First Look at the Inhibitory Potential of Urospatha sagittifolia (Araceae) Ethanolic Extract for Bothrops atrox Snakebite Envenomation [PDF]
Toxins, 2022 Bothrops atrox snakebites are a relevant problem in the Amazon basin. In this biodiverse region, the ethnomedicinal approach plays an important role as an alternative to antivenom therapy. Urospatha sagittifolia (Araceae) is a plant used for this purpose;
Antonio L. Vera-Palacios +7 more
doaj +2 more sources
Inflammatory Profile Associated with Secondary Infection from Bothrops atrox Snakebites in the Brazilian Amazon [PDF]
Toxins, 2023 Bothrops snakebite envenomation (SBE) is consider an important health problem in Brazil, where Bothrops atrox is mainly responsible in the Brazilian Amazon.
Távila Tatiane Amorim Cavalcante +18 more
doaj +2 more sources
Venom complexity of Bothrops atrox (common lancehead) siblings [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Variability in snake venoms is a well-studied phenomenon. However, sex-based variation of Bothrops atrox snake venom using siblings is poorly investigated. Bothrops atrox is responsible for the majority of snakebite accidents in the Brazilian
Daniela Miki Hatakeyama +15 more
doaj +2 more sources
Bothrops atrox and Bothrops lanceolatus Venoms In Vitro Investigation: Composition, Procoagulant Effects, Co-Factor Dependency, and Correction Using Antivenoms [PDF]
Toxins, 2023 Bothrops venoms are rich in enzymes acting on platelets and coagulation. This action is dependent on two major co-factors, i.e., calcium and phospholipids, while antivenoms variably neutralize venom-related coagulopathy effects.
Sébastien Larréché +10 more
doaj +2 more sources
Release of Cytokines in the Peritoneal Fluid of C57BL/6 Mice After Bothrops jararaca and Bothrops atrox Venom Injection [PDF]
ToxinsThe release of cytokines in the peritoneal fluid after stimulation with Bothrops atrox and Bothrops jararaca venoms is a crucial process in the inflammatory response triggered by these venoms.
Adriana da Silva Fernandes Ribas +4 more
doaj +2 more sources
Renal Effects and Nitric Oxide Response Induced by Bothrops atrox Snake Venom in an Isolated Perfused Kidney Model [PDF]
ToxinsThe snakes from the genus Bothrops are responsible for most of the ophidic accidents in Brazil, and Bothrops atrox represents one of these species. Envenomation by these snakes results in systemic effects and is often associated with early mortality ...
Terentia Batista Sa Norões +4 more
doaj +2 more sources
Comparative gender peptidomics of Bothrops atrox venoms: are there differences between them? [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Bothrops atrox is known to be the pit viper responsible for most snakebites and human fatalities in the Amazon region. It can be found in a wide geographical area including northern South America, the east of Andes and the Amazon basin ...
Adriana Simizo +5 more
doaj +3 more sources
Exploring the Profile of Cell Populations and Soluble Immunological Mediators in Bothrops atrox Envenomations [PDF]
Toxins, 2023 Bothrops atrox envenomations are common in the Brazilian Amazon. The venom of B. atrox is highly inflammatory, which results in severe local complications, including the formation of blisters.
Kerolaine Fonseca Coelho +12 more
doaj +2 more sources
Bothrops atrox, the most important snake involved in human envenomings in the amazon: How venomics contributes to the knowledge of snake biology and clinical toxinology [PDF]
Toxicon: X, 2020 Bothrops atrox snakes are mostly endemic of the Amazon rainforest and is certainly the South American pit viper responsible for most of the snakebites in the region. The composition of B.
Wuelton Marcelo Monteiro +15 more
doaj +2 more sources