Results 31 to 40 of about 8,036 (150)

Bothrops (Fer-de-lance) snakebites in the French departments of the Americas (Martinique and Guyana): Clinical and experimental studies and treatment by immunotherapy.

PLoS Neglected Tropical Diseases, 2023
Snakebite envenomation is a relevant medical hazard in French Guiana and Martinique, two French territories in the Americas. All snakebite envenomations in Martinique are inflicted by the endemic viperid species Bothrops lanceolatus, whereas Bothrops ...
Dabor Resiere, Hatem Kallel, Jonathan Florentin, Stephanie Houcke, Hossein Mehdaoui, José María Gutiérrez, Remi Neviere   +6 more
doaj   +2 more sources

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source

Endothelium, Platelets, and Coagulation Factors as the Three Vital Components for Diagnosing Bleeding Disorders: A Simplified Perspective with Clinical Relevance

International Journal of Clinical Practice, Volume 2022, Issue 1, 2022., 2022
Bleeding disorders are a major group of hematological disorders, which are highly prevalent in the world. Excessive bleeding can result in serious consequences including hypoperfusion and cardiac arrest. The body has its selfmechanism to control excessive bleeding which is termed hemostasis.
Abhinav Bhattarai, Sangam Shah, Sara Bagherieh, Omid Mirmosayyeb, Sangharsha Thapa, Sandip Paudel, Pawan Gyawali, Pitambar Khanal, Sanja Stankovic   +8 more
wiley   +1 more source

Hematologic parameters of captive Bothrops atrox (Squamata: viperidae) [PDF]

, 2022
The breeding of venomous snakes in captivity for research purposes and mainly as a source of pharmaceutical products highlights the need to determine hematological parameters for monitoring and ensuring a healthy breeding populationThe complete blood ...
André Luiz Quagliatto Santos, Líria Queiroz Luz Hirano, Pereira, Heloisa Castro, Letícia Prata Juliano Dimatteu Telles, Maísa Paschoal Rios, Pereira, Heloisa   +5 more
core   +1 more source

Bothrops venom-induced hemostasis disorders in the rat: Between Scylla and Charybdis.

PLoS Neglected Tropical Diseases, 2023
Hemostasis impairment represents the most threatening consequence of Viperidae envenoming, notably with Bothrops genus. In the French departments of America, B. atrox envenomation in French Guiana may lead to bleeding while B. lanceolatus envenomation in
Sébastien Larréché, Lucie Chevillard, Georges Jourdi, Simon Mathé, Aurélie Servonnet, Bérangère S Joly, Virginie Siguret, Jean-Philippe Chippaux, Bruno Mégarbane   +8 more
doaj   +1 more source

Comparative Hemostatic Effects of <i>Bothrops</i> spp. and <i>Daboia russelii</i> Venoms. [PDF]

Biochem Res Int
Venoms from Bothrops species and Daboia russelii are among the leading causes of venom‐induced coagulopathy and snakebite‐related deaths. In this study, we comparatively evaluated the biochemical composition and hemostatic effects of venoms from seven Bothrops species and D. russelii using protein profiling and functional coagulation assays.
Malchias-Pires GM, Romanazzi M, Almeida JR, Williams J, Vijayakumar P, Gilabadi S, Ferreira Júnior RS, Vaiyapuri S, Pucca MB.   +8 more
europepmc   +2 more sources

Bothrops atrox from Ecuadorian Amazon: Initial analyses of venoms from individuals [PDF]

, 2021
Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includes Ecuadorian territories. It comprises a large distribution, which could contribute to the genetic and venomic variation identified in the species.
Salazar Valenzuela, David, da Silva, Saulo L., Mendes, Bruno, Palma Patiño, Ricardo Sebastián, de Almeida, José R., Medina Villamizar, Evencio, Proaño Bolaños, Carolina   +6 more
core   +2 more sources

Purificación de fosfolipas A2 a partir de veneno de Bothrops atrox [PDF]

, 1999
La fosfolipasa A2 (PLA2) fue purificada a partir de veneno de serpiente de Bothrops atrox (Sensu lato) de Chiriguaná (Colombia) por cromatografía de exclusión sobre Sephadex G-75, de donde se obtuvieron cinco fracciones, una de ellas con actividad ...
B. Quevedo, Ramírez-Ávila, J., López, E., J. Ramírez-Ávila, Quevedo, B., E. López   +5 more
core   +2 more sources

Ação de venenos de serpentes brasileiras sôbre a alexina ou complemento

Memorias do Instituto Oswaldo Cruz, 1947
O autor estudou a ação inativante, sôbre o complemento de cobaia, alguns venenos de serpentes brasileiras pertencentes às famílias dos Elapideos e Crotalideos.
F. da Rocha Lagôa
doaj   +1 more source

Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms.

PLoS ONE, 2019
BACKGROUND:It is known that local tissue injuries incurred by snakebites are quickly instilled causing extensive, irreversible, tissue destruction that may include loss of limb function or even amputation.
Marcelo A Strauch, Marcelo Amorim Tomaz, Marcos Monteiro-Machado, Bruno Lemos Cons, Fernando Chagas Patrão-Neto, Jhonatha da Mota Teixeira-Cruz, Matheus da Silva Tavares-Henriques, Pâmella Dourila Nogueira-Souza, Sara L S Gomes, Paulo R R Costa, Edgar Schaeffer, Alcides J M da Silva, Paulo A Melo   +12 more
doaj   +1 more source