Results 31 to 40 of about 7,766 (180)

Análisis inmunoenzimático (ELISA) para determinar niveles de IgG anti Bothrops atrox en accidente ofídico Immunoenzymatic determination of IgG anti bothrops atrox levels after snake bites

Iatreia, 1993
Se desarrolló un método de inmunización de conejos con veneno de Bothrops atrox con el fin de preparar antisueros y estandarizar un inmunoanálisis (ELISA) para medir niveles de IgG en pacientes con accidente ofídico. La respuesta Inmune de los conejos se
John J. Estrada, Rafael Otero Patiño, Luz E. Posada, Sadoh Molina   +3 more
doaj   +1 more source

Dermatopathological findings of Bothrops atrox snakebites: A case series in the Brazilian Amazon. [PDF]

PLoS Negl Trop Dis
Background Bothrops venom consists primarily of metalloproteinase and phospholipase A2 toxins, which are responsible for the acute inflammatory, coagulant and hemorrhagic action following snakebite. The local effects of snakebite envenomation by Bothrops species are particularly prevalent yet poorly studied, but include pain, edema, erythema ...
Albuquerque Barbosa FB, Raad RS, Santos Ibiapina HN, Freire Dos Reis M, Neves JCF, Andrade RV, Nascimento TP, Valle FF, Casewell NR, Sachett J, Sartim MA, Monteiro W, Costa AG, Lima Ferreira LC.   +13 more
europepmc   +5 more sources

Development of Nanobodies Against Hemorrhagic and Myotoxic Components of Bothrops atrox Snake Venom. [PDF]

Front Immunol, 2020
L'envenimation des serpents est un problème de santé publique négligé dans le monde entier. Les antivenins produits à partir de plasma hyperimmun animal restent le traitement standard des morsures de serpent. Bien qu'efficaces contre les effets systémiques, les antivenins conventionnels ont une efficacité limitée contre les lésions tissulaires locales.
Bailon Calderon H, Yaniro Coronel VO, Cáceres Rey OA, Colque Alave EG, Leiva Duran WJ, Padilla Rojas C, Montejo Arevalo H, García Neyra D, Galarza Pérez M, Bonilla C, Tintaya B, Ricciardi G, Smiejkowska N, Romão E, Vincke C, Lévano J, Celys M, Lomonte B, Muyldermans S.   +18 more
europepmc   +8 more sources

Functional diversity of snakes is explained by the landscape composition at multiple areas of influence

Ecology and Evolution, Volume 13, Issue 7, July 2023., 2023
This study investigated the impact of roads and landscape composition on the functional diversity of snakes in the Orinoco region of Colombia. The results suggest that landscape composition affects the functional diversity of both road‐killed snakes and those inhabiting the adjacent vegetation within an area of influence ranging from 250 to 2000 m. The
Mónica Rincón‐Aranguri, Felipe A. Toro‐Cardona, Sandra P. Galeano, Lilia Roa‐Fuentes, Nicolás Urbina‐Cardona   +4 more
wiley   +1 more source

Bothrops (Fer-de-lance) snakebites in the French departments of the Americas (Martinique and Guyana): Clinical and experimental studies and treatment by immunotherapy.

PLoS Neglected Tropical Diseases, 2023
Snakebite envenomation is a relevant medical hazard in French Guiana and Martinique, two French territories in the Americas. All snakebite envenomations in Martinique are inflicted by the endemic viperid species Bothrops lanceolatus, whereas Bothrops ...
Dabor Resiere, Hatem Kallel, Jonathan Florentin, Stephanie Houcke, Hossein Mehdaoui, José María Gutiérrez, Remi Neviere   +6 more
doaj   +2 more sources

Comparison of phylogeny, venom composition and neutralization by antivenom in diverse species of bothrops complex. [PDF]

PLoS Neglected Tropical Diseases, 2013
In Latin America, Bothrops snakes account for most snake bites in humans, and the recommended treatment is administration of multispecific Bothrops antivenom (SAB--soro antibotrópico).
Leijiane F Sousa, Carolina A Nicolau, Pedro S Peixoto, Juliana L Bernardoni, Sâmella S Oliveira, José Antonio Portes-Junior, Rosa Helena V Mourão, Isa Lima-dos-Santos, Ida S Sano-Martins, Hipócrates M Chalkidis, Richard H Valente, Ana M Moura-da-Silva   +11 more
doaj   +1 more source

Evolutionary convergence of muscle architecture in relation to locomotor ecology in snakes

Journal of Anatomy, Volume 242, Issue 5, Page 862-871, May 2023., 2023
Snakes with different ecologies differ in the axial musculature with aquatic species having more robust muscles. Arboreal species on the other hand typically have longer muscle‐tendon units. Abstract The epaxial muscles in snakes are responsible for locomotion and as such can be expected to show adaptations in species living in different environments ...
Adrien Mathou, Xavier Bonnet, Karim Daoues, Rémi Ksas, Anthony Herrel   +4 more
wiley   +1 more source

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source

Ontogenetic variations in the venom proteome of the Amazonian snake Bothrops atrox [PDF]

Proteome Science, 2006
Abstract Background Bothrops atrox is responsible for the majority of snakebite accidents in the Brazilian Amazon region. Previous studies have demonstrated that the biological and pharmacological activities of B. atrox venom alter with the age of the animal.
Sousa Marcelo V, Paba Jaime, López-Lozano Jorge L, Shevchenko Andrej, Shevchenko Anna, Guércio Rafael AP, Ricart Carlos AO   +6 more
openaire   +3 more sources

Photobiomodulation Therapy to Treat Snakebites Caused by Bothrops atrox: A Randomized Clinical Trial. [PDF]

JAMA Intern Med
ImportanceBothrops venom acts almost immediately at the bite site and causes tissue damage.ObjectiveTo investigate the feasibility and explore the safety and efficacy of low-level laser therapy (LLLT) in reducing the local manifestations of B atrox envenomations.Design, Setting, and ParticipantsThis was a double-blind randomized clinical trial ...
Carvalho ÉDS, Souza ARDN, Melo DFC, de Farias AS, Macedo BBO, Sartim MA, Caggy MC, Rodrigues BA, Ribeiro GS, Reis HN, Araújo FQ, da Silva IM, Sachett A, Sampaio VS, Balieiro AADS, Zamuner SR, Vissoci JRN, Cabral LN, Monteiro WM, Sachett JAG.   +19 more
europepmc   +3 more sources