Results 151 to 160 of about 8,168 (216)
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The vasopressor action of angiotensin in the snake Bothrops jararaca

Comparative Biochemistry and Physiology Part A: Physiology, 1992
1. Carotid blood pressure from anesthetized B. jararaca snakes was recorded in order to study angiotensin action in this reptile. 2. Whereas [Asn1,Val5] AII and AIII were less potent than [Asp1,Ile5] AII and [Asp1,Val5] AII, [Sar1,Ile5] AII was slightly more potent. 3. Captopril abolished the responses to AI (0.01-3 micrograms/kg). 4.
M C, Breno, Z P, Picarelli
openaire   +2 more sources

Immunization with liposome-encapsulated Bothrops jararaca venom

Toxicon, 2000
The venom of Bothrops jararaca (BjV) snake was encapsulated into liposomes. The toxicity and ability of the resultant liposomes to protect mice were evaluated. No acute toxicity was found in mice, when liposomes were subcutaneously injected whereas the same dose of venom emulsified in Freund's adjuvant caused the mice to die.
V T, Carvalho   +3 more
openaire   +2 more sources

rJararacin, a recombinant disintegrin from Bothrops jararaca venom: Exploring its effects on hemostasis and thrombosis.

Archives of Biochemistry and Biophysics, 2023
Integrins are a family of heterodimeric transmembrane receptors which link the extracellular matrix to the cell cytoskeleton. These receptors play a role in many cellular processes: adhesion, proliferation, migration, apoptosis, and platelet aggregation,
Victor David   +8 more
semanticscholar   +1 more source

The humoral immune responses of patients bitten by the snake Bothrops jararaca (jararaca)

Toxicon, 1990
The isotype and specificity of antibodies produced by patients bitten by B. jararaca and submitted to serum therapy were studied. The IgG anti-B. jararaca antibodies have large individual dispersion, starting to appear 10 days after the first bite and increasing to at least 80 days after the bite.
M O, Domingos   +3 more
openaire   +2 more sources

Hesperetin as an inhibitor of the snake venom serine protease from Bothrops jararaca.

Toxicon, 2021
The majority (90%) of the snakebite envenomation in Brazil accounts for Bothrops from the Viperidae family. Some snake venom serine proteases provoke blood coagulation in ophidian accident victims because of their fibrinolytic activity and one of those ...
Roney V. dos Santos   +4 more
semanticscholar   +1 more source

Blood-clotting Activity of the Venom of Bothrops jararaca

Nature, 1959
THE well-known blood-clotting activity of the venom from snakes of various species of the genus Bothrops has been attributed to its proteolytic activity1, although Michl2 (using paper electrophoresis) and Holz and Raudonat3 (using fractional precipitation with ammonium sulphate) have presented evidence against this point of view.
O B, HENRIQUES   +2 more
openaire   +2 more sources

Synergistic effect of serine protease inhibitors and a bothropic antivenom in reducing local hemorrhage and coagulopathy caused by Bothrops jararaca venom.

Toxicon, 2021
Snakebite accidents are a public health problem that affects the whole world, causing thousands of deaths and amputations each year. In Brazil, snakebite envenomations are caused mostly by snakes from the Bothrops genus.
G. M. Silva   +9 more
semanticscholar   +1 more source

Angiotensin receptor in the heart of Bothrops jararaca snake

European Journal of Pharmacology, 2001
Angiotensin II interacts with specific cell surface angiotensin AT1 and AT2 receptors and, in some vertebrates, with an atypical angiotensin AT receptor. This study was designed to characterize the angiotensin receptor in the heart of Bothrops jararaca snake.
M C, Breno, C S, Porto, Z P, Picarelli
openaire   +2 more sources

Bothrops jararaca Wied

1971
The karyotypes presented were obtained from short term blood cultures. The sex chromosomes, male — ZZ, female — ZW correspond to the 4th pair of macrochromosomes. The karyotypes are from a male specimen of Santa Catarina and from a female specimen of Sao Paulo, Brazil. Both are preserved in the Collection of the Instituto Butantan.
Maria Luiza Beçak   +6 more
openaire   +1 more source

Separation of the coagulant components of Bothrops jararaca venom

Toxicon, 1970
The venom of Bothrops jararaca has been separated into two distinct coagulant components by chromatography on DEAE cellulose, and the presence of an inhibitor in the crude venom detected.
K W, Denson, W E, Rousseau
openaire   +2 more sources

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