Results 11 to 20 of about 4,982 (208)

Spectroscopic and thermal characterization of alternative model biomembranes from shed skins of Bothrops jararaca and Spilotis pullatus [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2009
Recently, there has been an interest in the use of shed snake skin as alternative model biomembrane for human stratum corneum. This research work presented as objective the qualitative characterization of alternative model biomembranes from Bothrops ...
André Rolim Baby, Áurea Cristina Lemos Lacerda, Fernanda Daud Sarruf, Claudinéia Aparecida Sales de Oliveira Pinto, Vladi Olga Consiglieri, Cristina Helena dos Reis Serra, Maria Valéria Robles Velasco, Yoshio Kawano, Telma Mary Kaneko   +8 more
doaj   +5 more sources

Bothrops jararaca Snake Venom Inflammation Induced in Human Whole Blood: Role of the Complement System [PDF]

Frontiers in Immunology, 2022
The clinical manifestations of envenomation by Bothrops species are complex and characterized by prominent local effects that can progress to tissue loss, physical disability, or amputation. Systemic signs can also occur, such as hemorrhage, coagulopathy,
Thyago Bispo Leonel, Joel José Megale Gabrili, Carla Cristina Squaiella-Baptistão, Trent M. Woodruff, John D. Lambris, Denise V. Tambourgi   +5 more
doaj   +2 more sources

Release of Cytokines in the Peritoneal Fluid of C57BL/6 Mice After Bothrops jararaca and Bothrops atrox Venom Injection [PDF]

Toxins
The release of cytokines in the peritoneal fluid after stimulation with Bothrops atrox and Bothrops jararaca venoms is a crucial process in the inflammatory response triggered by these venoms.
Adriana da Silva Fernandes Ribas, Kemily Stephanie de Godoi, Sávio Stefanini Sant’Anna, Marisa Maria Teixeira da Rocha, Wilmar Dias da Silva   +4 more
doaj   +2 more sources

Hematology, Clinical Biochemistry, and Blood Cell Morphology Features of Captive Bothrops jararaca From Southeast Brazil [PDF]

Veterinary Clinical Pathology, Volume 54, Issue 3, Page 221-229, September 2025.
ABSTRACT Background Snakebite envenomation is a worldwide public health issue, particularly relevant to low and middle‐income countries. Bothrops spp. antivenom is needed for snakebite treatment, which requires the maintenance of healthy snakes in captivity.
Amanda O. Alcantara, Bianca M. M. Reis, Juliana G. Fonseca, Maíra A. C. Sousa, Vitor Hugo A. Roxo, Guilherme J. Souza, Fúlvia de Fátima A. Castro, Guilherme N. Souza, Jorlan Fernandes, Elba Regina S. Lemos, Aline M. Souza   +10 more
wiley   +2 more sources

Understanding Local Reactions Induced by Bothrops jararaca Venom: The Role of Inflammatory Mediators in Leukocyte–Endothelium Interactions [PDF]

Biomedicines
In recent years, extensive research has delved into the pathophysiology of local reactions triggered by Bothrops snake venoms. Even though antivenom works well at reducing death and systemic effects, it is still not very effective in treating local ...
Bianca Cestari Zychar, Luís Roberto C. Gonçalves   +1 more
doaj   +2 more sources

Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca: De Novo Assembly and Analysis of Novel Toxic Proteins [PDF]

Toxins
Previous proteomic studies of viperid venom revealed that it is mainly composed of metalloproteinases (SVMPs), serine proteinases (SVSPs), phospholipase A2 (PLA2), and C-type lectins (CTLs).
Joseph Espín-Angulo, Doris Vela
doaj   +2 more sources

Proteomics and life-history variability of Endogenous Phospholipases A2 Inhibitors (PLIs) in Bothrops jararaca plasma. [PDF]

PLoS ONE
In Brazil, the genus Bothrops is responsible for most ophidian accidents. Snake venoms have a wide variety of proteins and peptides exhibiting a broad repertoire of pharmacological and toxic effects that elicit systemic injury and characteristic local ...
Caroline Serino-Silva, Caroline Fabri Bittencourt Rodrigues, Jackson Gabriel Miyamoto, Daniela Miki Hatakeyama, Victor Koiti Kavazoi, Marisa Maria Teixeira Da Rocha, Aparecida Sadae Tanaka, Alexandre Keiji Tashima, Karen de Morais-Zani, Kathleen Fernandes Grego, Anita Mitico Tanaka-Azevedo   +10 more
doaj   +2 more sources

Effect of Seaweed-Derived Fucoidans from Undaria pinnatifida and Fucus vesiculosus on Coagulant, Proteolytic, and Phospholipase A₂ Activities of Snake Bothrops jararaca, B. jararacussu, and B. neuwiedi Venom [PDF]

Toxins
Background: Snakebite envenomation (SBE) causes diverse toxic effects in humans, including disability and death. Current antivenom therapies effectively prevent death but fail to block local tissue damage, leading to an increase in the severity of ...
Camila Castro-Pinheiro, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Ana Cláudia Rodrigues da Silva, Corinna A. Dwan, Samuel S. Karpiniec, Alan Trevor Critchley, Andre Lopes Fuly   +7 more
doaj   +2 more sources

Structural evolution of the whole mitochondrial genome and phylogenetic inference in snakes (Squamata: Serpentes), including the undescribed mitogenome of the Brazilian endemic and critically endangered pitviper Bothrops insularis [PDF]

Genetics and Molecular Biology
Evolutionary analyses of mitogenomes have provided insights into species evolution and conservation. Studies on snakes revealed a higher diversity especially involving variation in tRNA clusters.
Igor Salles-Oliveira, José S.L. Patané, Milton Y. Nishiyama- Júnior, Maria José J. Silva   +3 more
doaj   +2 more sources

Can anti-bothropstoxin-I antibodies discriminate between Bothrops jararaca and Bothrops jararacussu venoms? [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Snakes of the genus Bothrops, popularly known as pit vipers, are responsible for most cases of snakebite in Brazil. Within this genus, Bothrops jararacussu and B.
Ricardo Teixeira Araujo, Carlos Corrêa-Netto, Leonora Brazil-Más, Caio Raony Farina Silveira, Irene Fernandes, Russolina Benedeta Zingali   +5 more
doaj   +2 more sources