Results 41 to 50 of about 19,548 (244)
Botulinum neurotoxin A, blinding, and bias [PDF]
Developmental Medicine & Child Neurology, 2019 This article is commented on by Day on page 159 of this issue.
Tandy Hastings‐Ison, Kerr Graham
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Clinical Anatomy, EarlyView.ABSTRACT Myofascial pain syndrome (MFPS) causes chronic shoulder pain. Supraspinatus and infraspinatus, rotator cuff muscles innervated by the suprascapular nerve, are commonly affected. Intramuscular botulinum neurotoxin (BoNT) injections near motor points (i.e., visible nerve branch entry sites used as a proxy for motor endplates) are an effective ...
Dave Osinachukwu Duru +5 more
wiley +1 more source
Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells [PDF]
, 2016 Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human
Binz, T. +3 more
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Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives Functional constipation (FC) is common in childhood, significantly impacting quality of life. Since the 2014 international guideline, new evidence has been published, and methods on making guidelines have developed. This treatment guideline for FC in children aged 0–18 years is a collaborative effort of the European and North ...
Morris Gordon +17 more
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Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy
Toxins, 2015 Botulinum neurotoxin is one of the deadliest biological toxins known to mankind and is able to cause the debilitating disease botulism. The rapid detection of the different serotypes of botulinum neurotoxin is essential for both diagnosis of botulism and
Alison C. Savage +3 more
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Toxins, 2021 Breast reconstruction after mastectomy is commonly performed using transverse rectus abdominis myocutaneous (TRAM) flap. Previous studies have demonstrated that botulinum neurotoxin injections in TRAM flap surgeries lower the risk of necrosis and allow ...
Kyu-Ho Yi +4 more
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Botulinum neurotoxins: Future innovations
Medicine, 2023 Botulinum neurotoxins (BoNTs) are multi-domain proteins whose potent and selective actions on nerve endings have led to innovations in both basic and clinical science. The various BoNT domains are responsible for binding to gangliosides and proteins associated with nerve cell membranes, internalization into the cell, and cleavage of one or more SNARE (
Brideau-Andersen, Amy +2 more
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Microbial communities and functional diversity in seafood
JSFA reports, EarlyView.Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi +3 more
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Neuronal selectivity of botulinum neurotoxins
Toxicon, 2020 Botulinum neurotoxins (BoNTs) are highly potent toxins responsible for a severe disease, called botulism. They are also efficient therapeutic tools with an increasing number of indications ranging from neuromuscular dysfunction to hypersecretion syndrome, pain release, depression as well as cosmetic application.
Poulain, Bernard +2 more
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Clinical Relevance of Botulinum Toxin Immunogenicity [PDF]
, 2012 Botulinum toxin type A is a 150 kD protein produced by Clostridium botulinum, which exists in a complex with up to six additional proteins. The ability of botulinum toxin to inhibit acetylcholine release at the neuromuscular junction has been exploited ...
Reiner Benecke
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