Botulinum toxin injections as a method for chemically denervating skeletal muscle to test functional hypotheses: a pilot study in Lepomis cyanellus [PDF]
, 2007 In this study, we demonstrate that botulinum toxin can be used to chemically denervate muscles to test functional hypotheses. We injected research-grade type A botulinum toxin complex into pectoral fin abductors (abductor superficialis) of green sunfish (
Gibb, Alice C., O'Neill, Matthew W.
core +1 more source
Reply to “Neurophysiological Testing to Diagnose Stiff‐Person Spectrum Disorder”
Movement Disorders Clinical Practice, EarlyView.
João Moura +5 more
wiley +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A.
Journal of the American Chemical Society, 2017 The highly poisonous botulinum neurotoxins, produced by the bacterium Clostridium botulinum, act on their hosts by a high-affinity association to two receptors on neuronal cell surfaces as the first step of invasion.
Christoffer Hamark +6 more
semanticscholar +1 more source
Botulinum toxin therapy: functional silencing of salivary disorders. [PDF]
, 2017 Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary ...
Lovato, A +4 more
core
Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]
, 2012 When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson +95 more
core +3 more sources
Early Levodopa Therapy in Tyrosine Hydroxylase Deficiency
Movement Disorders Clinical Practice, EarlyView.
Claudio M. de Gusmao +4 more
wiley +1 more source
Review of published research on primary dysautonomia of domestic animals
Veterinary Record, EarlyView.Abstract An article published in 1992 by Marion M. Pollin and I.R. Griffiths reviewed the topic of primary dysautonomias of the autonomic nervous system of unidentified origin in multiple domestic species, specifically cats, dogs and horses. Thirty‐one years later, we appear no closer to identifying the causal agents of these strikingly similar ...
Tanith Harte +3 more
wiley +1 more source
Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia
The Journal of Headache and Pain, 2017 BackgroundDespite their huge epidemiological impact, primary headaches, trigeminal neuralgia and other chronic pain conditions still receive suboptimal medical approach, even in developed countries.
G. Sandrini +4 more
semanticscholar +1 more source
Recent Developments in Engineering Non-Paralytic Botulinum Molecules for Therapeutic Applications
ToxinsThis review discusses the expanding application of botulinum neurotoxin in treating neurological conditions. The article specifically explores novel approaches to using non-paralytic botulinum molecules.
Aisha Zhantleuova +5 more
doaj +1 more source