Results 101 to 110 of about 20,701 (223)

Study for the structures of the HA complexes produced by Clostridium botulinum type A mutant strain [PDF]

, 2012
Clostridium botulinum produces seven neurotoxin (NTX) serotypes, classified from as A to G. In culture, NTX forms protein complexes by association with non-toxic components, such as nontoxic-nonhemagglutinin (NTNH) and hemagglutinins (HA1, HA2, HA3).
Ma, Shaobo
core   +1 more source

Recent Developments in Engineering Non-Paralytic Botulinum Molecules for Therapeutic Applications

Toxins
This review discusses the expanding application of botulinum neurotoxin in treating neurological conditions. The article specifically explores novel approaches to using non-paralytic botulinum molecules.
Aisha Zhantleuova, Charlotte Leese, Anna P. Andreou, Altynay Karimova, Guy Carpenter, Bazbek Davletov   +5 more
doaj   +1 more source

Spore Germination Apparatus in Clostridium botulinum Group I and II [PDF]

, 2017
Spore germination is a significant step in the transformation of dormant spores into exponentially dividing vegetative cells, and in the case of Clostridium botulinum in the formation of the deadly botulinum neurotoxin.
Pye, Hannah
core  

Increased levels of SV2A botulinum neurotoxin receptor in clinical sensory disorders and functional effects of botulinum toxins A and E in cultured human sensory neurons

Journal of Pain Research, 2011
Yiangos Yiangou1 Uma Anand1,2, William R. Otto2, Marco Sinisi3, Michael Fox3, Rolfe Birch3 Keith A. Foster4, Gaurav Mukerji1,5, Ayesha Akbar1,6, Sanjiv K.
Yiangou Y, An, U, Otto WR, Sinisi M, Fox M, Birch R, Foster KA, Mukerji G, Akbar A, Agarwal SK, An, P   +12 more
doaj  

Type E Botulinum Neurotoxin-Producing Clostridium butyricum Strains Are Aerotolerant during Vegetative Growth

mSystems, 2019
Clostridium butyricum, the type species of the genus Clostridium, is considered an obligate anaerobe, yet it has been shown to grow in the presence of oxygen. C. butyricum strains atypically producing the botulinum neurotoxin type E are the leading cause
Serena Camerini, Lucia Marcocci, Lara Picarazzi, Egidio Iorio, Irene Ruspantini, Paola Pietrangeli, Marco Crescenzi, Giovanna Franciosa   +7 more
doaj   +1 more source

Development of Enzyme-linkage Immunosorbent Assay Against Type B of Clostridium Botulinum: a Preliminary Study [PDF]

, 2011
Clostridium botulinum neurotoxin (BoNTs) is one of the causes of economic loss in the livestockindustry. This economic loss would be as a direct result when animals poisoned by BoNTs or indirectlywhen the livestock products are contaminated by BoNTs ...
Depamede, S. N. (S), Kisworo, D. (D)
core  

An Investigation of Immunogenicity of Chitosan-Based Botulinum Neurotoxin E Binding Domain Recombinant Candidate Vaccine via Mucosal Route

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: Botulism syndrome is caused by serotypes A-G of neurotoxins of Clostridium genus. Neurotoxin binding domain is an appropriate vaccine candidate due to its immunogenic activity.
Mohammad Javad Bagheripour, Firouz Ebrahim, Abbas Hajizadeh, Shahram Nazarian, Jamil Zargan, Jamal Rashidiani   +5 more
doaj  

Electrochemical impedance spectroscopy biosensor for detection of active botulinum neurotoxin

Sensing and Bio-Sensing Research, 2014
The standard method for the detection of botulinum neurotoxin is currently the mouse bioassay which is considered to be the most reliable method for the detection of the active form of this toxin.
Jennifer Halliwell, Alison C. Savage, Nicholas Buckley, Christopher Gwenin   +3 more
doaj   +1 more source

Protocol and Demographics of the RELY-CD Study: Assessing Long-Term Clinical Response to Botulinum Neurotoxin in Cervical Dystonia

Toxins
The RELY-CD study investigated the long-term clinical response to botulinum neurotoxin type A in cervical dystonia within a multicenter, real-world setting.
Benjamin Waeschle, John-Ih Lee, Tristan Kölsche, Robin Jansen, Marta Banach, Stanislaw Ochudlo, Małgorzata Tyślerowicz, Piotr Sobolewski, Sara Sánchez Valiente, Eva López-Valdés, Pablo Mir, Silvia Jesús, Elena Ojeda-Lepe, Ewa Papuć, Pilar Sánchez Alonso, Gabriel Salazar, Georg Comes, Holger Stark, Philipp Albrecht   +18 more
doaj   +1 more source

Reduction in Post-Botulinum Toxin Flu-like Symptoms After Injection with Incobotulinum Toxin [PDF]

, 2014
OBJECTIVE: To determine if patients reporting flu-like symptoms (FLS) after botulinum toxin (BoNT) injections are less susceptible to this reaction after incobotulinum toxin.
George, Edwin, Shneyder, Natalya
core   +1 more source