Results 161 to 170 of about 46,671 (223)

Elucidating the activation mechanism of botulinum neurotoxin a: role of α-clostripain and NTNH. [PDF]

Sci Rep
Pitel S, Barnea A, Diamant E, Torgeman A, Noy-Porat T, Falach R, Zichel R, Hayouka Z, Ben David A.   +8 more
europepmc   +1 more source

Microfluidic Nanobiosensor Detection of Botulinum Neurotoxin Serotype A. [PDF]

ACS Omega
Srinivasan S, Letran K, Nasir S, Sung K, Lam J, Wang Y, Duncan TV.   +6 more
europepmc   +1 more source

Immunological Considerations of Polysorbate as an Excipient in Botulinum Neurotoxin Type A Formulations: A Narrative Review. [PDF]

Toxins (Basel)
Martin MU, Frevert J, Park JY, Cui H, Curry A, Loh WQ.   +5 more
europepmc   +1 more source

RTP004 Peptide Binds to Botulinum Neurotoxin, Increases Cell Surface Binding, and Enhances Cellular SNAP-25 Cleavage. [PDF]

Toxins (Basel)
Batista AF, Singh R, Lee F, Zhuo S, Leonoudakis D, Gallagher CJ.   +5 more
europepmc   +1 more source

A translational preclinical strategy for chronic spinal cord injury: neuroprotective and regenerative potential of botulinum neurotoxin type A combined with muscle atrophy prevention via electrostimulation. [PDF]

Mil Med Res
Mastrorilli V, Luvisetto S, Ruggieri V, Raparelli G, Madaro L, Paggi LA, Parisi C, De Santa F, De Angelis F, D'Elia A, Massari R, Amadio S, Rossetto O, Vacca V, Caruso M, Sferrazza G, Pavone F, Marinelli S.   +17 more
europepmc   +1 more source

Presynaptic Terminal Proteins and Nicotinic Receptors Are Depleted from Mouse Parasympathetic Ganglionic Junctions Paralysed with Botulinum Neurotoxin Type A. [PDF]

Toxins (Basel)
Al-Sabi A, Lawrence GW.
europepmc   +1 more source

Proteolytic Activities and Immunological Effects of Light Chains of Botulinum Neurotoxin A1, A2 and A3 Subtypes. [PDF]

Toxins (Basel)
Liao Y, Hu X, Wang J, Lu J, Yu S, Yu Y, Wu W.   +6 more
europepmc   +1 more source

Cell-Penetrating Botulinum Neurotoxin Type A Proteins Alleviate Skeletal Muscle Hypertrophy with Associated Alterations of Mitochondrial Homeostasis. [PDF]

Toxins (Basel)
Li L, Wei X, Jiang L, Gao Z, Liu J.
europepmc   +1 more source

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Botulinum Neurotoxins: Mechanism of Action

Toxicon, 2013
Botulinum neurotoxins are used clinically for conditions characterized by hyperexcitability of peripheral nerve terminals and hypersecretory syndromes. These neurotoxins are synthesized as precursor proteins with low activity, but their effects are mediated by the active form of the neurotoxin through a multistep mechanism.
Giampietro Schiavo
exaly   +3 more sources