Results 161 to 170 of about 4,608 (197)
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Toxicology and Applied Pharmacology, 1986
To determine the efficacy of 3,4-diaminopyridine (3,4-DAP) as a potential treatment for botulism, its effect on the survival times of mice injected with type A, B, E, or F botulinum toxin (Bo Tx) was examined. Mice were injected ip with 10, 20, or 40 LD50 of Bo Tx. Three hours later, when the mice displayed signs of botulism, half of each group of mice
L S, Siegel +2 more
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To determine the efficacy of 3,4-diaminopyridine (3,4-DAP) as a potential treatment for botulism, its effect on the survival times of mice injected with type A, B, E, or F botulinum toxin (Bo Tx) was examined. Mice were injected ip with 10, 20, or 40 LD50 of Bo Tx. Three hours later, when the mice displayed signs of botulism, half of each group of mice
L S, Siegel +2 more
openaire +2 more sources
European Urology, 2009
Previous studies in humans, dogs, and rats have shown that intraprostatic injection of botulinum neurotoxin type A (BoNTA) reduces gland size.To investigate the role of eventual impairment of sympathetic, parasympathetic, and sensory nerves to gland atrophy after intraprostatic BoNTA administration.Adult male Wistar rats weighing 300-350 g were used ...
João, Silva +6 more
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Previous studies in humans, dogs, and rats have shown that intraprostatic injection of botulinum neurotoxin type A (BoNTA) reduces gland size.To investigate the role of eventual impairment of sympathetic, parasympathetic, and sensory nerves to gland atrophy after intraprostatic BoNTA administration.Adult male Wistar rats weighing 300-350 g were used ...
João, Silva +6 more
openaire +2 more sources
Urology, 2007
Botulinum neurotoxins are increasingly used in treatment for hyperactive detrusor and sphincter function. Although reported results are promising, conditions in some patients are refractory. We report what we believe to be the first urologic case of therapy failure possibly induced by botulinum toxin antibodies after just one injection and discuss ...
Heinrich, Schulte-Baukloh +6 more
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Botulinum neurotoxins are increasingly used in treatment for hyperactive detrusor and sphincter function. Although reported results are promising, conditions in some patients are refractory. We report what we believe to be the first urologic case of therapy failure possibly induced by botulinum toxin antibodies after just one injection and discuss ...
Heinrich, Schulte-Baukloh +6 more
openaire +2 more sources
BJU International, 2015
Objective To investigate the potential distribution of radiolabelled botulinum neurotoxin type A (Bo NT /A) in the CNS after bladder injection in normal rats, by using the gamma‐emitting radionuclide ...
Dionysia, Papagiannopoulou +3 more
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Objective To investigate the potential distribution of radiolabelled botulinum neurotoxin type A (Bo NT /A) in the CNS after bladder injection in normal rats, by using the gamma‐emitting radionuclide ...
Dionysia, Papagiannopoulou +3 more
openaire +2 more sources
Toxicon, 2008
Botulinum neurotoxin type A (BoNT/A) is largely employed in the therapy of a wide array of human syndromes characterized by a hyperactivity of peripheral cholinergic nerve terminals. In this study we determined the extent of diffusion of three different commercial preparations of botulinum neurotoxin type A by developing a high sensitive test based on ...
Carli Luca +2 more
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Botulinum neurotoxin type A (BoNT/A) is largely employed in the therapy of a wide array of human syndromes characterized by a hyperactivity of peripheral cholinergic nerve terminals. In this study we determined the extent of diffusion of three different commercial preparations of botulinum neurotoxin type A by developing a high sensitive test based on ...
Carli Luca +2 more
openaire +1 more source
Cortical Rewiring Following Peripheral Injection of Botulinum Neurotoxin Type A
Toxicon, 2022Verediana Massa +5 more
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Movement Disorders, 2008
AbstractHereditary spastic paraplegia (HSP) is characterized by lower extremity spasticity. Symptomatic therapy generally includes physical therapy and oral antispastic agents, in selected cases intrathecal baclofen. Because of the positive results in other treatments of spasticity, the use of botulinum neurotoxin type A (BoNT‐A) might also be ...
Martin J, Hecht +6 more
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AbstractHereditary spastic paraplegia (HSP) is characterized by lower extremity spasticity. Symptomatic therapy generally includes physical therapy and oral antispastic agents, in selected cases intrathecal baclofen. Because of the positive results in other treatments of spasticity, the use of botulinum neurotoxin type A (BoNT‐A) might also be ...
Martin J, Hecht +6 more
openaire +2 more sources
Injection of Botulinum Neurotoxin Type A Alleviates Neuropathic Orofacial Pain
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2016NOBORU NOMA, YOSHIKI IMAMURA
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Anatomical Proposal for Botulinum Neurotoxin Injection for Glabellar Frown Lines
Toxins, 2022Kyu-Ho Yi, Ji-Hyun Lee, Hyewon Hu
exaly