Results 1 to 10 of about 8,876 (115)

Botulinum Neurotoxin Type A in the Treatment of Facial Seborrhea and Acne: Evidence and a Proposed Mechanism [PDF]

Toxins, 2021
Intradermal injection of botulinum neurotoxin is a frequently performed procedure in aesthetic dermatology to improve facial skin tone, texture, fine wrinkles, and enlarged pores.
Nark-Kyoung Rho, Young-Chun Gil
doaj   +2 more sources

Botulinum neurotoxin type A in the interdisciplinary treatment of sialorrhea in adults and children—update and practice recommendations [PDF]

Frontiers in Neurology, 2023
Sialorrhea is defined as a chronic excessive flow of saliva from the mouth, often with adverse consequences for health and quality of life of patients.
Wolfgang H. Jost, Tobias Bäumer, Andrea Bevot, Ulrich Birkmann, Carsten Buhmann, Maria Grosheva, Orlando Guntinas-Lichius, Rainer Laskawi, Sebastian Paus, Christina Pflug, A. Sebastian Schroeder, Björn Spittau, Armin Steffen, Bernd Wilken, Martin Winterholler, Steffen Berweck   +15 more
doaj   +2 more sources

Rapid SERS Detection of Botulinum Neurotoxin Type A [PDF]

Nanomaterials, 2023
Surface-enhanced Raman scattering (SERS) is a powerful technique for decoding of 2-5-component mixes of analytes. Low concentrations of analytes and complex biological media are usually non-decodable with SERS.
Alexei Subekin, Rugiya Alieva, Vladimir Kukushkin, Ilya Oleynikov, Elena Zavyalova   +4 more
doaj   +2 more sources

Bulging of the Masseter Muscle Following Botulinum Neurotoxin Type A Injection [PDF]

Plastic and Reconstructive Surgery, Global Open
Summary:. Botulinum neurotoxin toxin type A is widely used in the management of facial paralysis to reduce synkinesis and improve facial symmetry. Although the masseter muscle is not innervated by the facial nerve, aberrant reinnervation may lead to ...
Lukas Naef, MD, Epameinondas Gousopoulos, MD, MSc, PhD, Florian Alexander Huber, MD, Pietro Giovanoli, MD   +3 more
doaj   +2 more sources

Surface Acoustic Wave Immunosensor for Detection of Botulinum Neurotoxin

Sensors, 2023
A Love-type acoustic wave sensor (AT-cut quartz substrate, SiO2 guiding layer) with a center frequency of approximately 120 MHz was used to detect a simulant of pathogenic botulinum neurotoxin type A—recombinant of BoNT-A light chain—in liquid samples ...
Michał Grabka, Krzysztof Jasek, Zygfryd Witkiewicz   +2 more
doaj   +1 more source

Diversity of the Genomes and Neurotoxins of Strains of Clostridium botulinum Group I and Clostridium sporogenes Associated with Foodborne, Infant and Wound Botulism

Toxins, 2020
Clostridium botulinum Group I and Clostridium sporogenes are closely related bacteria responsible for foodborne, infant and wound botulism. A comparative genomic study with 556 highly diverse strains of C. botulinum Group I and C.
Jason Brunt, Arnoud H. M. van Vliet, Andrew T. Carter, Sandra C. Stringer, Corinne Amar, Kathie A. Grant, Gauri Godbole, Michael W. Peck   +7 more
doaj   +1 more source

Pan-Genomic Analysis of Clostridium botulinum Group II (Non-Proteolytic C. botulinum) Associated with Foodborne Botulism and Isolated from the Environment

Toxins, 2020
The neurotoxin formed by Clostridium botulinum Group II is a major cause of foodborne botulism, a deadly intoxication. This study aims to understand the genetic diversity and spread of C. botulinum Group II strains and their neurotoxin genes.
Jason Brunt, Arnoud H. M. van Vliet, Sandra C. Stringer, Andrew T. Carter, Miia Lindström, Michael W. Peck   +5 more
doaj   +1 more source

Adult Intestinal Toxemia Botulism

Toxins, 2020
Intoxication with botulinum neurotoxin can occur through various routes. Foodborne botulism results after consumption of food in which botulinum neurotoxin-producing clostridia (i.e., Clostridium botulinum or strains of Clostridium butyricum type E or ...
Richard A. Harris, Fabrizio Anniballi, John W. Austin   +2 more
doaj   +1 more source

Structural Basis of Botulinum Toxin Type F Binding to Glycosylated Human SV2A: In Silico Studies at the Periphery of a Lipid Raft

Biomolecules, 2022
Botulinum neurotoxins are the deadliest microbial neurotoxins in humans, with a lethal dose of 1 ng/kg. Incidentally, these neurotoxins are also widely used for medical and cosmetic purposes.
Fodil Azzaz, Didier Hilaire, Jacques Fantini   +2 more
doaj   +1 more source

Single Application of A2 NTX, a Botulinum Toxin A2 Subunit, Prevents Chronic Pain Over Long Periods in Both Diabetic and Spinal Cord Injury–Induced Neuropathic Pain Models

Journal of Pharmacological Sciences, 2012
Botulinum toxin type A is a unique candidate for inhibition of pain transmission. In the present study we attempted to see the beneficial actions of A2 neurotoxin (NTX), an active subunit of botulinum toxin type A.
Lin Ma, Jun Nagai, Yuki Sekino, Yoshitaka Goto, Shinji Nakahira, Hiroshi Ueda   +5 more
doaj   +1 more source