Results 11 to 20 of about 121,700,018 (217)

Comparison of botulinum neurotoxin type A formulations in Asia

Clinical, Cosmetic and Investigational Dermatology, 2018
Jürgen Frevert,1 Ki Young Ahn,2 Mee Young Park,3 Owen Sunga4 1Merz Pharmaceuticals GmbH, Frankfurt, Germany; 2Dr. Ahn’s Plastic and Aesthetic Surgical Clinic, Daegu, South Korea; 3Department of Neurology, Yeungnam University School of Medicine,
Frevert J, Ahn KY, Park MY, Sunga O
doaj   +6 more sources

Camelid single-domain antibody ciA-B5 recognizes light chain of botulinum neurotoxin type A by ELISA

Antibody Reports
Camelid single-domain antibody (VHH) ciA-B5 detects by ELISA the light chain (LC) of the botulinum neurotoxin type A (BoNT/A).
Nga Quynh Pham, Tam Trang Mai, Tran Bao Anh Dang, Anh Minh Nguyen, Anh Thao Nguyen, Anh Phuong Tran, Tran Nhat Minh Dang, Van Khanh Tran, Hoa Quang Le   +8 more
doaj   +2 more sources

Neurologic uses of botulinum neurotoxin type A

Neuropsychiatric Disease and Treatment, 2007
John P Ney, Kevin R JosephMadigan Army Medical Center, Neurology Service, Tacoma, WA, USAAbstract: This article reviews the current and most neurologic uses of botulinum neurotoxin type A (BoNT-A), beginning with relevant historical data, neurochemical ...
John P Ney, Kevin R Joseph
doaj   +1 more source

Blockade of Glutamate Release by Botulinum Neurotoxin Type A in Humans: A Dermal Microdialysis Study [PDF]

Pain Research and Management, 2014
BACKGROUND: The analgesic action of botulinum neurotoxin type A (BoNTA) has been linked to the blockade of peripheral release of neuropeptides and neurotransmitters in animal models; however, there is no direct evidence of this in humans.
Larissa Bittencourt da Silva, Ali Karshenas, Flemming W Bach, Sten Rasmussen, Lars Arendt-Nielsen, Parisa Gazerani   +5 more
doaj   +2 more sources

Overview of botulinum neurotoxin-producing clostridia in soils in France

Microbiology Spectrum
Soil is a known reservoir of human pathogens, including botulinum neurotoxin-producing clostridia. However, the occurrence and distribution of botulinum neurotoxin types in French soils are unknown, prompting this study.
Caroline Le Maréchal, Adeline Huneau, Sébastien Solanas, Amandine Avouac, Léa Jambou, Apolline Roux, Line Boulonne, Sandra Rouxel, Claudy Jolivet, Typhaine Poezevara, Marianne Chemaly, Alain Hartmann   +11 more
doaj   +2 more sources

Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports

Clinical, Cosmetic and Investigational Dermatology, 2013
Sebastian Torres,1 Mark Hamilton,2 Elena Sanches,4 Polina Starovatova,3 Elena Gubanova,3 Tatiana Reshetnikova51Di Stefano Velona Clinic, Catania, Italy; 2Hamilton Face Clinic, Dublin, Ireland; 3Preventive Medicine Clinic "Vallex M", Moscow ...
Torres S, Hamilton M, Sanches E, Starovatova P, Gubanova E, Reshetnikova T   +5 more
doaj   +1 more source

Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison. [PDF]

Acta Crystallogr F Struct Biol Commun
For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Yao Z, Xu L, Lu Y, Gong H, Sun X, Zhao Y, Chen J, Yang L, Chen Q, Yang W.   +9 more
europepmc   +2 more sources

Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody. [PDF]

Int J Mol Sci, 2022
Tetanus and Botulinum type B neurotoxins are bacterial metalloproteases that specifically cleave the vesicle-associated membrane protein VAMP at an identical peptide bond, resulting in inhibition of neuroexocytosis.
Fabris F, Šoštarić P, Matak I, Binz T, Toffan A, Simonato M, Montecucco C, Pirazzini M, Rossetto O.   +8 more
europepmc   +3 more sources

Nature of intracellular type A botulinum neurotoxin [PDF]

Applied and Environmental Microbiology, 1981
The neurotoxin in cells of young Clostridium botulinum type A culture was extracted with lysozyme. Highly purified neurotoxin preparation, obtained by processing the extract in two chromatographic steps had only unnicked (single-chain) molecules of molecular weight comparable to that of the dichains isolated from type A crystals.
E P, Krysinski, H, Sugiyama
openaire   +2 more sources

Botulinum Neurotoxin Type-A for the Treatment of Atypical Odontalgia [PDF]

Pain Medicine, 2016
Atypical odontalgia (AO), a subform of persistent idiopathic facial pain, is defined as a continuous toothache in which a thorough examination reveals no dental pathology. AO is believed to be a neuropathic condition, given that some cases are preceded by dental procedures.
María-Luz, Cuadrado, Héctor, García-Moreno, José-Antonio, Arias, Juan A, Pareja   +3 more
openaire   +2 more sources