Results 51 to 60 of about 121,794,009 (205)

In the human urothelium and suburothelium, intradetrusor botulinum neurotoxin type A does not induce apoptosis: preliminary results [PDF]

open access: yes, 2010
Intradetrusor injections of botulinum neurotoxin type A (BoNTA) are emerging as the preferred second-line treatment for neurogenic and idiopathic overactive bladder (OAB).
Khan, Shahid   +13 more
core   +1 more source

Recombinant botulinum toxin as a new stage in the development of botulinum toxin therapy. Possibilities and perspectives of use in neurological practice

open access: yesНеврология, нейропсихиатрия, психосоматика, 2022
Currently, eight natural serotypes of botulinum neurotoxin (BNT-A-G, -X) are known. The mechanism of action of all BNT serotypes is presynaptic blockade of SNARE transport proteins (Soluble N-ethylmaleimide-sensitive factor [NSF] Attachment Protein ...
R. K. Shikhkerimov, E. V. Istomina
doaj   +1 more source

Efficacy of IncobotulinumtoxinA (BoNT‐A) Injections in Upper Limb Task‐Specific and Position‐Dependent Tremors

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific tremors (TST) and position‐dependent tremors (PDT) are rare isolated focal tremors that impair fine motor control with few effective treatment options. Although botulinum neurotoxin (BoNT) is effective in other tremor syndromes, its evidence in these tremor subtypes remains limited.
Elizabeth K. Boyd   +3 more
wiley   +1 more source

Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A [PDF]

open access: yes, 2008
Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Carmen Garcia   +5 more
core  

Transcranial Direct Current Stimulation Combined with Botulinum Neurotoxin Type A Injections for Treatment of Upper Limb Intention Tremor in Multiple Sclerosis: A Case Report

open access: yesCase Reports in Neurology, 2021
Upper limb intention tremor is a common cause of disability in multiple sclerosis (MS). Transcranial direct current stimulation (tDCS) is an emerging form of brain stimulation used to improve sensorimotor impairments in many neurological disorders. Here,
Salvatore Facciorusso   +7 more
doaj   +1 more source

Cholinergic inputs to motoneurons in the spinal cord augment focal muscle spasticity in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cholinergic premotor inputs to motoneurons support high levels of motor output when required. However, the possible role of these inputs in pathologically elevated muscle tone has not been characterised. To address this, we examined the modulatory effect of spinal acetylcholine (ACh) on experimental spastic paralysis ...
Patrik Meglić   +10 more
wiley   +1 more source

Pain trajectories in children and adolescents with cerebral palsy: A longitudinal population‐based register study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Four pain trajectories were identified in a population‐based register study of 4887 children and adolescents with cerebral palsy: (1) increasing trend, low probability of experiencing pain (20.28%), (2) increasing trend, high probability of experiencing pain (30.30%), (3) decreasing trend (26.85%), and (4) consistently high probability of experiencing ...
May Phyu Sin   +3 more
wiley   +1 more source

Anatomical Injection Guidelines for Glabellar Frown Lines Based on Ultrasonographic Evaluation

open access: yesToxins, 2021
When botulinum neurotoxin (BoNT) is injected to treat glabellar frown lines, the corrugator supercilia muscle (CSM) and procerus muscles are the main targets.
Soo-Bin Kim   +6 more
doaj   +1 more source

The Effect of Different Doses of Botulinum Toxin on Masseter Muscle in Patients with Bruxism.

open access: yesErbil Dental Journal, 2022
Background and Objectives: Botulinum toxin type A is produced by clostridium botulinum. It acts by inhibiting the release of acetylcholine from cholinergic neurons.
Kawa F. Dizaye, Sarezh Jamal Jalal
doaj  

Research progress on the application of botulinum toxin type A in the treatment of myogenous temporomandibular disorders [PDF]

open access: yes口腔疾病防治
Myogenous temporomandibular disorder (M-TMD) is one of the main subtypes of temporomandibular disorder (TMD) and typically manifests as masticatory myofascial pain; the incidence of TMD has been increasing annually in recent years. Botulinum toxin type A
CHEN Yifan, TANG Liangchen, CHEN Min’er, ZHANG Xiao, TANG Kuangyun, LI Zhiyong
doaj   +1 more source

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